Androfactory
Board Sponsor
ANDRO FACTORY's Gyno research
Can Androgen's in the body reverse Gyno? You decide.
During the research in making BULK-UP we located this article from Life Sciences regarding gyno and prohormone use. Research suggest that Androgens like the ones found in BULK-UP can actually reverse Gyno. Now we know that it would walking a tight rope to make any such claims being that we are not a pharmaceutical company and not branded as a 'New Drug".
BULK-UP like most ANDRO FACTORY products is DHEA based which was grandfathered in and not included in the anabolic steroid act therefor making it legal to sell as a dietary supplement and not a "New Drug". As long as you don't make claims that make disease, curing, preventing or reversing statements. Which we would never do!
But we can share articles and information that we come across while researching the Natural Prohormones found in our products; YOU might find this interesting.....
Cheers!
ANDRO FACTORY Strongest-Safest-Legal-Prohormones anywhere.
Here is one example of androgens helping with gyno. BULK-UP is an androgen based prohormone
Here is the source of the article
Life Sciences 69 (2001) 1465–1469
Measurement of androgen and estrogen receptors
in breast tissue from subjects with anabolic
steroid-dependent gynecomastia
L. Calzada*, J. Torres-Calleja, JM. Martinez, N. Pedrón
Unidad de Investigación Médica en Medicina Reproductiva, Instituto Mexicano del Seguro Social,
Apartado Postal 20-645, México D.F. C.P. 01001
Received 5 July 2000; accepted 22 January 2001
Discussion
Changes in endogenous hormone levels due to the administration of anabolic steroids have
been reported to cause gynecomastia. Exogenous steroid exposure may compete with en-
dogenous steroids for intracellular receptors causing breast enlargement [5]. These observa-
tions support the hypothesis that a hormonal environment may provide a setting favourable
for mammary glands to develop gynecomastia.
The results obtained suggest that in bodybuilders with gynecomastia, the hormonal status
is characterized by a clearly persistent estrogenic stimulation derived from the aromatization
of testosterone by a local increase in aromatase activity, which is probably induced by the
prolonged administration of anabolic steroids [5].
This study showed that the major concentration of ER is localized in the cytosol and nu-
cleus, possibly due to an increased estradiol level, which is a basic requisite for the hormone
response. Whereas the major concentration of AR is localized in the cytosol, the diminished
AR levels in the nucleus may be explained by the presence of salt-resistant receptors that
probably remain bound to the nuclear matrix.
Our data agree with previous studies demonstrating that the administration of anabolic ste-
roids caused a decrease in serum gonadotrophin and testosterone levels [16].
Finally, our findings suggest the following: first, that anabolic steroid administration for
prolonged periods may cause an excess of circulating estrogens, perhaps through the conver-
sion of testosterone to estrogens; second, a predominant estrogen effect on the breast may
produce breast enlargement; and third, the presence of estradiol and androgen receptors in
gynecomastia tissue suggests that gynecomastia is a hormone-dependent event.
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"Here is one example of androgen's helping with gyno. BULK-UP is an androgen based prohormone” please visit our website for more information
Invalid Link Removed
Can Androgen's in the body reverse Gyno? You decide.
During the research in making BULK-UP we located this article from Life Sciences regarding gyno and prohormone use. Research suggest that Androgens like the ones found in BULK-UP can actually reverse Gyno. Now we know that it would walking a tight rope to make any such claims being that we are not a pharmaceutical company and not branded as a 'New Drug".
BULK-UP like most ANDRO FACTORY products is DHEA based which was grandfathered in and not included in the anabolic steroid act therefor making it legal to sell as a dietary supplement and not a "New Drug". As long as you don't make claims that make disease, curing, preventing or reversing statements. Which we would never do!
But we can share articles and information that we come across while researching the Natural Prohormones found in our products; YOU might find this interesting.....
Cheers!
ANDRO FACTORY Strongest-Safest-Legal-Prohormones anywhere.
Here is one example of androgens helping with gyno. BULK-UP is an androgen based prohormone
Here is the source of the article
Life Sciences 69 (2001) 1465–1469
Measurement of androgen and estrogen receptors
in breast tissue from subjects with anabolic
steroid-dependent gynecomastia
L. Calzada*, J. Torres-Calleja, JM. Martinez, N. Pedrón
Unidad de Investigación Médica en Medicina Reproductiva, Instituto Mexicano del Seguro Social,
Apartado Postal 20-645, México D.F. C.P. 01001
Received 5 July 2000; accepted 22 January 2001
Discussion
Changes in endogenous hormone levels due to the administration of anabolic steroids have
been reported to cause gynecomastia. Exogenous steroid exposure may compete with en-
dogenous steroids for intracellular receptors causing breast enlargement [5]. These observa-
tions support the hypothesis that a hormonal environment may provide a setting favourable
for mammary glands to develop gynecomastia.
The results obtained suggest that in bodybuilders with gynecomastia, the hormonal status
is characterized by a clearly persistent estrogenic stimulation derived from the aromatization
of testosterone by a local increase in aromatase activity, which is probably induced by the
prolonged administration of anabolic steroids [5].
This study showed that the major concentration of ER is localized in the cytosol and nu-
cleus, possibly due to an increased estradiol level, which is a basic requisite for the hormone
response. Whereas the major concentration of AR is localized in the cytosol, the diminished
AR levels in the nucleus may be explained by the presence of salt-resistant receptors that
probably remain bound to the nuclear matrix.
Our data agree with previous studies demonstrating that the administration of anabolic ste-
roids caused a decrease in serum gonadotrophin and testosterone levels [16].
Finally, our findings suggest the following: first, that anabolic steroid administration for
prolonged periods may cause an excess of circulating estrogens, perhaps through the conver-
sion of testosterone to estrogens; second, a predominant estrogen effect on the breast may
produce breast enlargement; and third, the presence of estradiol and androgen receptors in
gynecomastia tissue suggests that gynecomastia is a hormone-dependent event.
Invalid Link RemovedInvalid Link Removed
"Here is one example of androgen's helping with gyno. BULK-UP is an androgen based prohormone” please visit our website for more information
Invalid Link Removed
