I am by no means a professional or expert on this topic but i too am on my first clen cycle and im planning on using benedryl for the third and sixth week.Ive done lots of research the past 4 or 5 months and it seems that if you use the benedryl then you should take 50mg -100mg at night before bed.Im going to try the 50 mg dosing and see how it works then possibly up it 25mg on the sixth week