Why is my Free Test so high?

[TylerDurden7]

I've been on 200mg cyp per week and blood tests have come back twice showing me hovering around 1000 ng/dl total test but around 44 ng/dl free. Doc is going to cut me down to 150 mg every week. Dont really want to cuz I'm feelin pretty good right now. Is there any reason why my free so high when compared to my total and is that dangerous enough to warrant the lowering of my dose?

 

[wearedbleedblue]

You're at supraphysiological levels right now. The body doesn't produce that much total or free test on its own generally. He wants to bring you down to more average levels. You're on TRT for low test right? Not just to build muscle?

 

[TylerDurden7]

Yea I'm on TRT for low test, but am definitely enjoying the anabolic effects of my current dose. The doc said my total was fine, but he was concerned with my free test being double what is normal. Why would my free levels be be so high when my total is just above normal?

 

[Philec48]

Your SHBG is probably low. Supraphysiological dosing such as yours will supress SHBG. On some lab scales 1000 ng/dl is above the upper range limit. Other health issues may also impact SHBG. Best to get thyroid and adrenals properly tested, and keep a watch on a1c and insulin levels.

 

[JanSz]

I've been on 200mg cyp per week and blood tests have come back twice showing me hovering around 1000 ng/dl total test but around 44 ng/dl free. Doc is going to cut me down to 150 mg every week. Dont really want to cuz I'm feelin pretty good right now. Is there any reason why my free so high when compared to my total and is that dangerous enough to warrant the lowering of my dose?

When on TRT
TotalTestosterone value is of secondary importance.

NEWER measure FreeT using direct assay, most of them are absolutely wrong.

Best way to monitor TRT is to have blood testing done

for Testosterone, at Quest Diagnostics
this test
Testosterone, Free, Bio/Total (LC/MS/MS) Code: 14966X

for Estradiol at LabCorp
this test

Estradiol, sensitive 140244 (3-70)

---------------------------------------------------


One wants to achieve two goals when aiming at testosterone level

SHBG(15-25)
and
BAT~575
BAT-BioAvailableTestosterone

When SHBG>25 aim at BAT~650
that should result with SHBG getting lower, given time

When SHBG<15 aim at
BAT~350
also keep E2 as high as possible, barring nipple issues
check and adjust thyroid, insulin/glucose and cholesterol
TT3-high
FT3-high
RT3-low

==================================

Quest Diagnostics do not have reliable Estradiol tests.
But their (very good) BAT test can be approximated using dr Vermulen chart.
This chart:
Invalid Link Removed

To monitor TRT
get from LabCorp (same blood draw):

43 --------- Estradiol, sensitive 140244 (3-70)
44 --------- Estrone, Serum
45 --------- Total Testosterone
46 --------- SHBG
47 --------- Albumin
48 --------- Dihydrotestosterone
49 --------- 3a-Androstanediol Glucuronide

BAT~575
corresponds to
FreeT(300-350)
obtained from chart.

............................................................
Without more information,
assuming that you need 200mg/week
make following changes:

Use EOD schedule (EveryOtherDay)

Use HCG

T-shot=29units=0.29cc=58mg=203mg/week
HCG-shot=160iu

do both shots one day next day free
use this needle for both shots:

BD Ultrafine II U-100 Insulin Syringe 31 Gauge 3/10cc 5/16inch Short Needle--1/2 Unit Markings 100/b Price: $27.80

It cost a lot, buy one box, then buy other syringes, see if you like them.
Post names if you find something worth recommending.
-----------

DHT must be within range.
Most of the time it is ok while on injectable testosterone

If it is low, that is the only situation when using Androgel is called for.

When chasing DHT, do not use any other transdermal testosterone, possibly with exception of Testogel.

Compounded T-crem/gels are of poor quality and their quality does not repeat from one to the next purchase.

..............
When forced to deal with very high SHBG newer use
Stanozolol, Winstrol
or
Danazol

either high TotalT will help
or
look for problems in

cholesterol
glucose/insulin
thyroid
adrenals



/
-----------------------------------------------------

 

[TylerDurden7]

Thank you Jansz for the informative post there bro. Im on a once a week schedule and just got injected with 150mg. If my levels were around 1000 ng/dl 7 days post inject of 200mg, where do you think they will be whilst on 150mg 7 days after?

 

[The Matrix]

I've been on 200mg cyp per week and blood tests have come back twice showing me hovering around 1000 ng/dl total test but around 44 ng/dl free. Doc is going to cut me down to 150 mg every week. Dont really want to cuz I'm feelin pretty good right now. Is there any reason why my free so high when compared to my total and is that dangerous enough to warrant the lowering of my dose?

200 is why to high to even start out on and typical protocol for a HRT clinic that follow cookie cuter methods. You need to get full evaluation of your hormones and most Dr's only do a half asked job, First of our bio T is more reflective of shbg and albumin not free T. Free T only makes up 1-2 % of active testosterone. Every one that I have seen on high dosages for testosterone usually end up with thyroid and adrenal issues down the road. may feel good at first but it will come around and bite you back in the ass.

Did your dr properly evaluate thyroid before TRT. So many guys have good t levels and e2 still feel like crap thats because they have hidden thyroid or adrenal issues that may be subclincal.

 

[TylerDurden7]

Doc checked thyroid and said it was all good. I feel good on 200mg a week and really didnt want to cut down, but he was persistent in saying my free test was way too high. Would rather go by feel than numbers but will give 150 a try for awhile and if not feelin as well let him know I suppose.

 

[Philec48]

Did he only test TSH? Unfortunately, many docs think that is sufficient for thyroid testing, even though TSH is not even a thyroid hormone.

Get total and free T3 and T4, and RT3 in addition to TSH at a minimum. TgAb and TPO also, even better.

Doc checked thyroid and said it was all good.

 

[The Matrix]

Did he only test TSH? Unfortunately, many docs think that is sufficient for thyroid testing, even though TSH is not even a thyroid hormone.

Get total and free T3 and T4, and RT3 in addition to TSH at a minimum. TgAb and TPO also, even better.

I have started to narrow down to ft3, ft4, rt3, and tsh 3 rd generation, ferritin TPO, TGAB for thyroid panel. To many people dr's say they are fine and they are not. One needs to look at symptoms not numbers. You give a lot of t is compensates for low thyroid for a bit then after a while your body will push back and that is where you are at now. Adjusting thyroid, adrenals, gh, e2 will allow for less need for testosteorne and better overall therapy.