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IBE Reverse: What do you think?

Are you interested in IBE's Reverse?

  • Definitely! This is honestly the most novel combination of ingredients available!

    Votes: 47 74.6%

  • Not so much, I don't really care about health supplements.

    Votes: 16 25.4%
  • Total voters
    63
datBtrue said:
...
Now I see why you are so excited about your "baby". Your potential market is huge...way beyond the bodybuilding community.

Make sure you file a patent application that also includes you not just IBE....
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I could not agree more, DB. I saw the following in the Life Extension Magazine. You probably have seen it, too:


GlaxoSmithKline Invests in Resveratrol Research

For years Life Extension magazine has been reporting on the multiple health benefits of resveratrol. We have urged members to incorporate this vital nutrient into their personal life-extension program. Now, pharmaceutical companies see the financial potential of creating a prescription drug from resveratrol compounds in order to treat age-related disease. Recently, pharmaceutical giant GlaxoSmithKline announced that it would acquire all outstanding shares of Sirtris Pharmaceuticals for $720 million in order to cash in on the life-extending promise of resveratrol-based compounds.1

Found in red grapes and wine, resveratrol has been credited with extending life span in a variety of organisms.2,3 Resveratrol mimics the life-extending properties of caloric restriction by activating enzymes called sirtuins, which influence a variety of aging-related metabolic functions.

Sirtris was founded in 2004 after Dr. David Sinclair of Harvard Medical School began publishing findings regarding resveratrol’s remarkable potential benefits.2 Sirtris’ stated goal is to discover and develop small molecules with anti-aging potential, and its research efforts have largely focused on enhancing the potency of resveratrol-based compounds.

GlaxoSmithKline evidently hopes to modify the resveratrol molecule to further bolster its bioavailability and effects. Such a modification would also allow the drug company to patent the new molecule and market it exclusively.

—Dale Kiefer

Reference

1. Available at: Invalid Link Removed. Accessed April 30, 2008.
2. Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003 Sep 11;425(6954):191-6.
3. Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 Nov 16;444(7117):337-42.​
 
strategicmove said:
I could not agree more, DB. I saw the following in the Life Extension Magazine. You probably have seen it, too:


GlaxoSmithKline Invests in Resveratrol Research

For years Life Extension magazine has been reporting on the multiple health benefits of resveratrol. We have urged members to incorporate this vital nutrient into their personal life-extension program. Now, pharmaceutical companies see the financial potential of creating a prescription drug from resveratrol compounds in order to treat age-related disease. Recently, pharmaceutical giant GlaxoSmithKline announced that it would acquire all outstanding shares of Sirtris Pharmaceuticals for $720 million in order to cash in on the life-extending promise of resveratrol-based compounds.1

Found in red grapes and wine, resveratrol has been credited with extending life span in a variety of organisms.2,3 Resveratrol mimics the life-extending properties of caloric restriction by activating enzymes called sirtuins, which influence a variety of aging-related metabolic functions.

Sirtris was founded in 2004 after Dr. David Sinclair of Harvard Medical School began publishing findings regarding resveratrol’s remarkable potential benefits.2 Sirtris’ stated goal is to discover and develop small molecules with anti-aging potential, and its research efforts have largely focused on enhancing the potency of resveratrol-based compounds.

GlaxoSmithKline evidently hopes to modify the resveratrol molecule to further bolster its bioavailability and effects. Such a modification would also allow the drug company to patent the new molecule and market it exclusively.

—Dale Kiefer

Reference

1. Available at: Invalid Link Removed. Accessed April 30, 2008.
2. Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003 Sep 11;425(6954):191-6.
3. Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 Nov 16;444(7117):337-42.​
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This is why when Fitnecise over at bb.com starts bashing Resveratrol and how it won't amount to anything etc etc etc. I just sit back and smile, because big pharma doesn't get involved unless there is potential.
 
LakeMountD said:
... big pharma doesn't get involved unless there is potential.
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Yep! Depending on the relative superiority of IBE Reverse/Triacetylated Resveratrol, GlaxoSmithKline might just consider making IBE a nice acquisition offer! :D
 
strategicmove said:
Yep! Depending on the relative superiority of IBE Reverse/Triacetylated Resveratrol, GlaxoSmithKline might just consider making IBE a nice acquisition offer! :D
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Hahaha riiiiight, somehow I see that one getting messy ;-). "Give us your company or we will decimate you!" lol :duel:
 
datBtrue said:
OR have the right "plugged in" white-shoes law firm represent you and "the boys" may let you have a taste. :)
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Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.
 
Very Quiet here today!

LakeMountD said:
Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.
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Is this the calm before the Grand Announcement "Reverse is finally here"?
 
Any news??

LakeMountD said:
Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.
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Is there any news on Reverse? It's the end of July.
 
Any Updates??

LakeMountD said:
Yeah, we put a patent on it, but I have a feeling they will get around it somehow on the basis of research. Bottom line is they can do it much more easily with the cash flow that they have.
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Please .......... any updates?
 
As always we are just waiting on one last company to finish up what they are doing so we can move forward. We already have the ingredients so there is no problem there. I will get some testers this week ;).
 
LakeMountD said:
LoL as am I. It has been a nightmare trying to get everything together. When you are trying to coordinate 4-5 different businesses it is always tough.
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would love to test for ya if I could. I am already spreading the news and the website amoung folks at work. folks here always ask me for supplement advice.
I can also maybe swing some folks to check it out at AlinBoard for ya since I am a respected member there.
 
Reverse!!

LakeMountD said:
Hahaha riiiiight, somehow I see that one getting messy ;-). "Give us your company or we will decimate you!" lol :duel:
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No news! That's scary. Makes me wonder if Glaxo Smithkline is indeed trying to do a hostile take-over of IBE.

That aside, when will Reverse be available to us?
 
rykkk said:
No news! That's scary. Makes me wonder if Glaxo Smithkline is indeed trying to do a hostile take-over of IBE.

That aside, when will Reverse be available to us?
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I posted a new thread in the IBE forum here! Pre-orders are ready to go. They are actually moving very quickly and there are limited quantities so if you want to secure yours I suggest you do it soon :thumbsup:
 
Thanks!!

LakeMountD said:
I posted a new thread in the IBE forum here! Pre-orders are ready to go. They are actually moving very quickly and there are limited quantities so if you want to secure yours I suggest you do it soon :thumbsup:
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Thanks for update -- I placed my order .....I'm all psyched!!

Just a few questions: 1) How many capsules per bottle? 2) What quantity of Triacetylated Resveratrol per capsule? and 3) Can I expect to receive this within a week's time as I leave for vacation in just over a week?
 
Pardon the ignorance but isnt this similar to how CLA works?

(via PPAR-deta expression)

""Dr. Evans and his team found that the PPAR-delta protein remodeled the muscle, producing more of the high-endurance Type 1 fiber. They genetically engineered a strain of mice whose muscles produced extra amounts of PPAR-delta. These mice grew more Type 1 fibers and could run twice as far as on a treadmill as ordinary mice before collapsing.

Given that people cannot be engineered in this way, Dr. Evans wondered whether levels of the PPAR-delta protein could be raised by drugs. Pharmaceutical companies have long tried to manipulate PPAR-delta because of its role in fat metabolism, and Dr. Evans found several drugs were available, although they had been tested for different purposes.
"""



corsaking said:
Interesting read about reservatrol on this link

Invalid Link Removed
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???
 
We are running a sale of this currently on IBE and it will be at Nutraplanet hopefully by the end of the week.

LMD
 
LakeMountD; said:
We are running a sale of this currently on IBE and it will be at Nutraplanet hopefully by the end of the week.

LMD
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Sounds good!
 
strategicmove said:
To everyone, his own, but I am still struggling to understand why every compound a bodybuilder uses has to "build muscle"! To my mind, building muscle is only one part of "bodybuilding". Besides, it is in the interest of a bodybuilder to make sure he is in sound physical health, otherwise, he would definitely compromise his goal of effective bodybuilding. So, in my opinion, supplements such as IBE Reverse belong squarely within a bodybuilder's arsenal.
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LakeMountD said:
I don't see a lot of bodybuilders spending >$45-50 on a health supplement. Most of them are young and don't understand the importance of health. Heck I'll admit that I didn't.
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If bodybuilders and general public alike cared about health as much as they care about outer appearances doctors and pharmaceuticals would be out of business :lol:

Superficiality of today's people amazes me (I guess I'm still naive IF IT INDEED AMAZES me). Speaking of the bodybuilders, many can't think outside of a square box. Extra muscle is dispensable for living, if you want to build more you have to create the right stimulus and provide the right building blocks. Because "the right stimulus" is inevitably a great stressor, you need to take care extra care of your health or you may as well flush all your gym efforts down the toilet.
Why do we have to bang our head against the wall until it cracks before we realize we shouldn’t have banged it in the first place ?! :think:

Because humans are stubborn creatures and can only be convinced of inefficiency of their own methods through personal experiences :frustrate: :fool2:

Yep, I'm guilty too ;)
 
dragonfly said:
If bodybuilders and general public alike cared about health as much as they care about outer appearances doctors and pharmaceuticals would be out of business :lol:

Superficiality of today's people amazes me (I guess I'm still naive IF IT INDEED AMAZES me). Speaking of the bodybuilders, many can't think outside of a square box. Extra muscle is dispensable for living, if you want to build more you have to create the right stimulus and provide the right building blocks. Because "the right stimulus" is inevitably a great stressor, you need to take care extra care of your health or you may as well flush all your gym efforts down the toilet.
Why do we have to bang our head against the wall until it cracks before we realize we shouldn’t have banged it in the first place ?! :think:

Because humans are stubborn creatures and can only be convinced of inefficiency of their own methods through personal experiences :frustrate: :fool2:

Yep, I'm guilty too ;)
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The quote in bold and italics is a good way to describe those who dose themselves up with prohormones or designer steroids or both , then use a forum for someone to recommend a good PCT.

Is it not time to step back for moment for all of us to reflect on what we are doing , where we want to be in bodybuilding terms to see if we are being swallowed up and taken in by the amount of claims in advertising that some supplement companies engage in.

We have just had the 2008 olympics with 2012 not too far away.Maybe we should be looking to the guys and girls who came away with gold silver and bronze , to see just what it takes to get to the level they have in terms of training, diet and supplementation.Somehow i dont think they will be walking into a health food store or logging on to a online supplement company to try a supplement just because its flavour of the month
 
I have a bottle sitting at home as we speak! can't wait to start taking it!

if you get sick or have any kind of illness,training comes to a screaching hault!

besides I want to be strong and healthy not just strong, and for many years to come!

looks like a very,very good health supplement!
 
Im going to be getting both my parents on this.... They are both over 55 (pops over 60) and dont look even 10 years younger....

Time to take advantage of a supplement like this before genetics begin to finally give way and their son gives em some gray hair... which they still have plenty of... Dang I got a long life to look forward too, thanks LMD, Thanks alot :D
 
poopypants said:
Im going to be getting both my parents on this.... They are both over 55 (pops over 60) and dont look even 10 years younger....

Time to take advantage of a supplement like this before genetics begin to finally give way and their son gives em some gray hair... which they still have plenty of... Dang I got a long life to look forward too, thanks LMD, Thanks alot :D
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I try to do...what I can do....when I can do it lol. Anyone know what movie that is from? (hint: comedy movie)

Actually I had a session I had to attend today on hydrolysis of acetyl esters of drugs and it made me smile to think about Reverse.

I wasn't the original person to think it up, I worked on finding which analog to use and the actual science behind why it will work. The original idea was from Dr.D.
 
LakeMountD said:
I try to do...what I can do....when I can do it lol. Anyone know what movie that is from? (hint: comedy movie)

Actually I had a session I had to attend today on hydrolysis of acetyl esters of drugs and it made me smile to think about Reverse.

I wasn't the original person to think it up, I worked on finding which analog to use and the actual science behind why it will work. The original idea was from Dr.D.
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there was a special about anti-aging on TV here in Japan, they make a big to do about reservatol and then at the end they ended it with that it only works with mice so far and no real testing has been done on humans. Another thing they mentioned is controlling calories. 3 times a day and not stuffing your face is the best way to control your weight and stay looking young...they proved it with monkeys and baboons.
Being a BB'er makes me think that if this is true, I am gonna die young and look like crap when I do.
 
alan1973 said:
there was a special about anti-aging on TV here in Japan, they make a big to do about reservatol and then at the end they ended it with that it only works with mice so far and no real testing has been done on humans. Another thing they mentioned is controlling calories. 3 times a day and not stuffing your face is the best way to control your weight and stay looking young...they proved it with monkeys and baboons.
Being a BB'er makes me think that if this is true, I am gonna die young and look like crap when I do.
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D@mn it! [email protected]@mn...d@mn!

I just found out Roy Walford died several years ago. Where was I?

Your post made me want to go get a picture of Roy and post it. He had practiced "life-extension calorie restricition" on himself for more than a decade.

From wikipedia:

Roy Lee Walford, M. D. (June 29, 1924 San Diego, California – April 27, 2004) was a pioneer in the field of life extension. He died at age 79 of respiratory failure as a complication of amyotrophic lateral sclerosis (commonly known as Lou Gehrig’s Disease). He was a leading advocate of calorie restriction as a method of life extension and health improvement.

Dr. Walford is credited with significantly furthering research on the discovery that laboratory mice, when fed a diet that restricted their caloric intake by 50% yet maintained nutritional requirements, could more than double their expected life span.​

Man I didn't even know the guy and yet this seriously saddens me. :(
 
DrkZoolander said:
been enjoying my bottle of Reverse quite well! been dosing 2 in am 1 in the evening.
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In terms of taking Reverse what does enjoy mean?

As it is a new supplement dont you think it would be better if you told us what impact it had on your health and training and any noticeable benefit you have gained from taking it .Enjoying in the context of taking a supplement means nothing
 
DrkZoolander said:
been enjoying my bottle of Reverse quite well! been dosing 2 in am 1 in the evening.
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I would even try one in the morn, and one in the evening. I have noticed increased energy, better recovery, and even my dark circles under my eyes are lightening up (which could be a sign of kidney function improving from blood being detoxified).

Adams
 
poopypants; said:
... im still waiting on mine.... cant wait to see what it does.
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....:food:
 
Even 1 capsule can be enough, I just want to point that out so people can see that it is actually very cost effective.
 
LakeMountD; said:
Even 1 capsule can be enough, I just want to point that out so people can see that it is actually very cost effective.
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I agree here, especially if one can absorb up to 100mg or 150mg resveratrol per capsule (and per day) at the employed level of potency.
 
REVERSE is absolutely awesome! Here's some detail for those interested: Invalid Link Removed
 
strategicmove said:
Night-time supplementation is great. Day-time supplementation, too!
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well, after finding it sold out on 3 sites, I finally found some and will be trying out soon. As always, I feel that if I cannot feel something a bit on lower doses, it is not worth my money. I will post feed back after the bottle is gone.
 
Even though I love IBE, my honest opinion is that it is way overpriced to be used as a staple in my arsenal. I know there are great ingrediants in it, but I just cant justify the cost. Not when I can buy 50 grams of trans-resveratol much cheaper than a bottle of reverse.
 
RedwolfWV said:
Even though I love IBE, my honest opinion is that it is way overpriced to be used as a staple in my arsenal. I know there are great ingrediants in it, but I just cant justify the cost. Not when I can buy 50 grams of trans-resveratol much cheaper than a bottle of reverse.
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I value your opinion, Red. It all comes down what you consider smart in a monetary sense.
 
Not all oral resveratrol products are born equal. And REVERSE is complex of advanced resveratrol plus other cool agents. Worth the price, in my opinion.
 
strategicmove said:
Not all oral resveratrol products are born equal.
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I agree. And I'm sure reverse is superior, but that does not make it affordable at least to me. Last time I looked it ran about $42 at Nutraplanet. Now maybe if it were in the low 30's I'd be more willing to try it out. This isn't a sup meant just to run a month and then take time off, its meant to run daily.

I'd also like to see some blood work showing that it really is more effective than trans resveratol. I'm not talking charts and graphs on how things should be, I mean real comparative blood tests.

Again, I'm not an IBE hater by any means. I love their stuff, and their people. This particular product is just way overpriced in my opinion. (as are many of the resveratol sups coming out)
 
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