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Trying to figure out what exactly is in P-slin and Anabolic Pump

TheMyth said:
My friend banged Jessica Alba's fat sister in hopes of getting to Jessica. He is now gay and lives in San Fransisco working at Banana Republic by day, and Starbucks by night. Let that be a lesson to everyone.
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i researched for this said fat sister and got nothing...i found a brother though...if your into that sort of thing. ...:sick:
 
nattydisaster said:
Ive read a few places that bitter melon and K-R-ALA and NA-R-ALA are both very good an mocking insulin. Maybe this is something we'll see in P-slin or AP in the future. I know DS sells that weird glucophase XR stuff thats just pure K-R-ALA, but ive read studies saying that NA-R-ALA is up to 70% more absorbed, and others saying its no different. Either way, seems like a cheap thing so stack with you P-Slin or AP.
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ALA does not "mock" Insulin but sensitizes muscle/fat cells to the effects of insulin.

AP and PSLIN is a new beast that does not require the presence of insulin to work. Hence, the reason that its a fantastic weight loss supplement when dosed correctly.
 
USPLabs said:
ALA does not "mock" Insulin but sensitizes muscle/fat cells to the effects of insulin.

AP and PSLIN is a new beast that does not require the presence of insulin to work. Hence, the reason that its a fantastic weight loss supplement when dosed correctly.
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Yes...which is something that sort of scares me...cuz im bulking, but i read the AP manual and im going to take it according to a carb-non responsive person, since it says most ectomorphs fall into that category...and im an ecto
 
nattydisaster said:
This product is sold by one manufacturer...seems sort of similar... ****** ***** ******** contains 25mg Cinnulin PF™ cinnamon extract per dose, 280mg each of Gymnema sylvestre and bitter melon (Momordica charantia) extracts and 16mg 1% corosolic acid banaba extract per dose. 2 doses per day before meals supports blood sugar health.** Somewhat bitter and may block ability to taste sweet for a few minutes. You would need to take 2-3 caps to equal the amount of some in P-slin so to speak...but again...its a similar but different product. I starred out the name in respect to Mullet and Jacob. Im a big fan of USPLabs.
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Again cinnulin senstizes cells to the effect of insulin. We use a pharmacuetical revelant dose of corosolic/tannins to achieve our end result.

If they are using 16mg of 1% banaba that is what .16mgs of corosolic acid.

Give it a go and lets us know.
 
USPLabs said:
Again cinnulin senstizes cells to the effect of insulin. We use a pharmacuetical revelant dose of corosolic/tannins to achieve our end result.

If they are using 16mg of 1% banaba that is what .16mgs of corosolic acid.

Give it a go and lets us know.
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Right...but some studies show effectiveness with 48mgs...so 3 caps...idk...not saying im gonna try it... why spend money on something to try it out, rather spend it on the real thing that i know already works.
 
USPLabs said:
Again cinnulin senstizes cells to the effect of insulin. We use a pharmacuetical revelant dose of corosolic/tannins to achieve our end result.

If they are using 16mg of 1% banaba that is what .16mgs of corosolic acid.

Give it a go and lets us know.
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In all honesty...would you use this as an ecto who is trying to bulk up? I dont care if i gain some fat or lose some fat...but i deff dont want to lose weight...and look smaller
 
nattydisaster said:
How is it possible that there is 3g of Glucosol in one capsule though? Thats what I dont get. And ive seen it standardized at 18% as well, and CNW sells banaba extract of corosolic acid for 20%. I think i just cant get my head around all this stuff...
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What are you talking about? I said 30mg of Pure Corosolic Acid.
 
nattydisaster said:
The antidiabetic activity of an extract from the leaves of Lagerstroemia speciosa standardized to 1% corosolic acid (Glucosol) has been demonstrated in a randomized clinical trial involving Type II diabetics. Subjects received a daily oral dose of Glucosol and blood glucose levels were measured. Glucosol at daily dosages of 32 and 48mg for 2 weeks showed a significant reduction in the blood glucose levels. Glucosol in a soft gel capsule formulation showed a 30% decrease in blood glucose levels compared to a 20% drop seen with dry-powder filled hard gelatin capsule formulation suggesting that the soft gel formulation has a better bioavailability than a dry-powder formulation.

Corosolic acid isolated from the fruit of Crataegus pinnatifida var. psilosa is a protein kinase C inhibitor as well as a cytotoxic agent.
Planta Med. 1998 Jun;64(5):468-70.
Corosolic acid isolated from the fruit of Cratoegus pinnatifida var. psilosa was tested for anticancer activity. Corosolic acid displayed about the same potent cytotoxic activity as ursolic acid against several human cancer cell lines. In addition, the compound displayed antagonistic activity against the phorbol ester-induced morphological modification of K-562 leukemic cells, indicating the suppression of protein kinase C (PKC) activity by the cytotoxic compound. Corosolic acid showed PKC inhibition with dose-dependent pattern in an in vitro PKC assay.




See now that makes more sense. 48mg of 1%. You made it seem like 48mg of pure 100%, thats why i said it was way too high
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The first abstract referenced blood glucose levels and did not delineate PPAR-Gamma mRNA expression, did not delineate the translocation of GLUT4, and, if you bothered to read the full study, said this:

Acute and chronic clinical studies of Corosolic acid (Glucosol™) formulations in normal subjects at daily dose of 48 mg Glucosol™ indicate that their blood sugar levels remain in the normal range (75 to 110 mg/dL) before, during and after the intake of Glucosol™
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.48mg of Corsolic Acid, therefore, exerted no effect on normal subject's fasting glucose (which isn't what we are after, anyway). As I said (is there an echo in here?), at least 30 mg of pure Corosolic Acid is needed to see results in vivo. Further, NIDDM is a disease not necessarily characterized by inefficient glucose metabolism, but of energy turnover ratios as a whole - this is why Lagerstroemia is so effective in this particular respect, as it creates positive energy turnover ratios via the activation of AMPk, deregulation of PPAR and so on.

You seem to be fixated on blood glucose levels, which are irrelevant in our weigh lifting respect - but, why? Because adipocytes are regulated via the same insulin-reactive pathways as myocytes; meaning that glucose metabolism may be through lipid uptake as well. You need to concern yourself with BE's ability to inhibit adipocyte differentiation by regulating genes responsible for energy expenditure (as I have mentioned multiple times). This affinity for energy regulation - differentiated in myo- versus adipocytes - separates P-Slin and Anabolic Pump from ALA/Cinnulin in that particular respect. Those products solely mitigate Insulin-Dependent pathways, whereas Anabolic Pump and P-Slin circumvent insulin, and directly regulate energy use at the genetic level. Therefore, 'lowered blood glucose' may be through GLUT4 regulation in adipocytes as well. This is not necessarily specific to this conversation, but merely attempting to assist you as a whole - you are inquisitive, which is positive, but extremely misinformed and misguided.
 
nattydisaster said:
In all honesty...would you use this as an ecto who is trying to bulk up? I dont care if i gain some fat or lose some fat...but i deff dont want to lose weight...and look smaller
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lol...If you buy AP will you be able to remove the cap?

The weight loss was adipose (which = fat), because CA/TA/LS-as-a-whole, regulates PPAR-Gamma expression; PPAR Gamma is a key gene in the energy expenditure ratio of adipocytes. As I said above, Anabolic Pump and P-Slin create a positive energy turnover ratio between myocytes and adipocytes - upregulating glucose storage in myocytes, and upregulating energy expenditure in adipocytes.

My advice:

Pick up some 20% CA, and dose it at 1.5g, 3 times daily, and tell me of your results. That is a lot of powder, by the way.
 
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