Anabolic Pump FAQ

dexterium

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USPLabs Anabolic Pump FAQ


Anabolic Pump is the first supplement to naturally allow you to build muscle and burn fat at the same time. By activating a protein called GLUT4 in every muscle cell, Anabolic Pump creates the proverbial 24-hour “Window of Opportunity” where the body utililizes nutrients at peak levels. Anabolic Pump is the first supplement to ever accomplish this feat that delivers a pronounced “re-composition” effect.

What is Anabolic Pump™?

Anabolic Pump is a new category of supplement called a Selective Insulin Muscle Sensitizer (SIMS).

Anabolic Pump™ is a SIMS. What is a SIMS?

A SIMS is a substance that stimulates muscle cells to suck up glucose better than Insulin. Unlike Insulin, a SIMS blocks glucose uptake in fat cells while promoting lipolysis(fat burning).

What does that mean?

Muscle growth and fat loss at an extremely fast rate while improving health!! Does not get any better..Really it does not.

Do you "FEEL" ANABOLIC-PUMP ™ or should we just believe you?

About 1 hour after the first dose those "In-Touch" with their bodies physiology will FEEL ANABOLIC-PUMP ™ working its magic. The "PUMPED" sensation is unavoidable. We are talking a REAL PUMP not just useless vasodilatation.

What happens if I do not feel the PUMP effect with Anabolic Pump™?

You may be slightly insulin resistant. You may be slightly resistant to the effects of Anabolic Pump™. Do not be discouraged if you do not "feel" Anabolic Pump™ working instantly as the others do. Just because you do not "feel" it working right away does not mean its not working. The exact opposite is happening. Anabolic Pump™ will help your body become more sensitive to the action of GLUT4! If you give up too early, you could be making a huge mistake so like any other supplement you need at least thirty days to judge.

Does Anabolic Pump™ need to be cycled?

No. The ingredients in Anabolic-Pump have been used around the world for centuries. The ingredients are proven safe and healthy. In clinical trials, the ingredients where studied for over 5 months improving health!

How does Anabolic Pump™ work?

ANABOLIC-PUMP™ makes food more anabolic by utilizing the natural power of the most anabolic hormone in the world - INSULIN. In our quest for perfection, diet is the ultimate key to success. Basic fact is that food is the most ANABOLIC substance in the world. You can inject insane amounts of testosterone and deca, along with handfuls of d-bol and anadrol and without the proper diet - YOU WILL NOT GROW! Ask around…this is bodybuilding gospel.

By harnessing the power of muscle specific insulin and food, ANABOLIC-PUMP™ takes NATURAL growth to UNNATURAL levels! Insulin is the most powerful anabolic hormone produced by the body, while food constitutes the very anabolic building blocks of muscle tissue. Professional bodybuilders administer insulin and eat insane amounts of food for RAPID strength and size gains. Insulin, without a doubt, forces muscle to grow FAST. Unfortunately, insulin also forces FAT CELLS to grow FASTER - YUCK! What you end up with is a HUGE mass of muscle covered in a THICK layer of FAT. In a Perfect world fat cells would be RESISTANT to the action of insulin. Like the moronic cliché "have your cake and eat it too" Why bake a cake and not eat it? With ANABOLIC-PUMP™ you eliminate the guilt of eating the cake. Yes, we've created the perfect world… well… the perfect supplement at least!

Anabolic Pump™ activates GLUT4 in striated muscle cells without exercise or insulin.

What is GLUT4?

GLUT4 is a transport protein that is responsible for glucose disposal in muscle and fat cells. GLUT4 is activated by Insulin, exercise, or Anabolic Pump™.

GLUT4 transport glucose into fat cells. How does Anabolic Pump™ block the action on GLUT4 in fat cells?

Like many mechanisms in science, we know they work without the exact mechanism of action. In scientific clinical studies, GLUT4 was measured by mRNA expression. Without a doubt, we know GLUT4 is suppressed in fat cells by measuring mRNA. We still need to find the exact mechanism.

Is Anabolic Pump™ a hormonal substance?


No!

Does AP spike insulin levels?

NO! On the contrary, Anabolic Pump™ will require the body to release less insulin.

Why?


Anabolic Pump™ increases GLUT4 so less insulin will be secreted due to the presence of GLUT4 stimulation from Anabolic Pump™.


What happens when I stop taking Anabolic Pump™?


You obviously lose the effect of Anabolic Pump™. While you shouldn't lose the gains you've made from Anabolic-Pump, you will not continue to build muscle and lose body fat as fast as you would while taking Anabolic-Pump. In other words, you will become normal again.

Does Anabolic Pump™ Stack well with other supplements?

Absolutely! Anabolic Pump™ could be the best STAND ALONE supplement ever created, but the addition of Anabolic Pump™ will super charge any supplement stack. It can double or even triple the effectiveness of any other supplement (besides insulin mimickers - see next question).

Should I avoid insulin mimicking supplements?


Definitely!

What are the best times for dosing Anabolic Pump™?

Please follow label instructions. Doses are structured around meals and pre/post workout nutrition.

Are there any special diet requirements with Anabolic Pump™?

Yes! Anabolic Pump™ needs Complex carbohydrates.

Why?

Remember that Anabolic Pump stimulates GLUT4. GLUT4 is a transport protein for glucose. The carbohydrates we eat all get metabolized to glucose for storage.

Do you recommend Anabolic Pump™ on a very low carbohydrate diet?


HECK NO!

Why?

Before the invention of Anabolic Pump™, you would have to drastically lower or even eliminate carbohydrates to lose body fat. In the reduction of carbohydrates, you would lose hard earned muscle in the dieting process to get super shredded. Carbohydrate is what fuels your brain and muscles to perform intensely in the gym. You eliminated carbohydrates. Your workouts suffer. You become moody and irritable. You are extremely lethargic and basically hate life. This is our sport, and we must make these sacrifices…well not any more! With Anabolic Pump™, you EAT MORE GAIN MUSCLE AND LOSE fat. Anabolic Pump™ eliminates the need to cut out carbohydrates! We have athletes who are eating up to 600 grams of carbs per day on Anabolic-Pump and still leaning out! Obviously, this is an extreme case but I think you get the idea.

What does this all mean?


Basically you're able to eat more quality food and gain muscle while losing fat at a super fast rate. In the past, you need steroids to accomplish such a feat!

How do I add Anabolic Pump™ into my diet?

This is a semi complex question that depends on your dieting goal. In general, I would not make any changes to my diet in the first 3 days. I would slowly increase my carbohydrate intake by 10 grams per meal after each dose of Anabolic Pump™.

What if I have more questions on Anabolic Pump™ and diet?

A sports nutritionist along with some Anabolic Pump™ nutrition experts will help you construct the perfect diet according to your goals FREE OF Charge!

-See Diet FAQ Below.
-Private Message Dexterium for diet construction, diet analysis and nutritional questions.
-Post questions in this thread or start a thread in the USPLabs forum on Anabolicminds.com


Are you pitching useless propaganda like the NO2 supplement market?

NO2 products are perception products when relating it to gaining muscle. You get the perception that it's working solely on the basis of the PUMP. The PUMP feel is a great marketing tool but beyond that N02 products do not build muscle. A great analogy is a balloon filled with helium; it will eventually lose its ability to float and will deflate. NO2 products DO HOLD merit in the endurance market.

Comparing ANABOLIC-PUMP ™ to NO2 is like comparing Testosterone to vitamin C.

Speaking of Testosterone, I use steroids and Growth hormone. Do I need this supplement?

YES! Imagine force feeding your muscles with glucose, Amino Acids in a super Anabolic state while PROMOTING FAT OXIDATION! You would be foolish not to use ANABOLIC-PUMP ™ . Human Growth hormone lowers your sensitivity to Insulin so ANABOLIC-PUMP ™ makes PERFECT sense

Is Anabolic Pump safe for use by drug tested athletes?

Yes.

Can women use Anabolic-Pump™?


Yes. Anabolic-Pump™ is not gender specific and the best natural toning agent ever created for a woman!

What if I wait longer than 15 minutes to take Anabolic-Pump™?


You should not wait! Please follow instructions as they are given to ensure you receive best possible results. Lethargy and mental confusion can set in if directions are not followed.
 
dexterium

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Diet FAQ
Is Anabolic-Pump better for bulking or cutting?

Both! Anabolic-Pump is a SIMS (Selective Insulin Muscle sensitizer). A SIMS is a compound that delivers glucose only to muscle cells and inhibiting glucose in fat cells. Anabolic-Pump is the only SIMS on the market!

Anabolic-Pump works like Insulin, but independent of Insulin. Insulin is an anabolic hormone that delivers glucose and amino acids into muscle cells and glucose into fat cells. In a perfect world insulin would be a compound that only delivers glucose into muscle cells. Anabolic-Pump is that perfect compound!

Whether you’re dieting or bulking, Anabolic-Pump is a must in any nutritional strategy.

Any nutritional strategy, How about a keto diet?


Since Anabolic Pump works by delivering glucose to muscle cells and inhibiting glucose in fat cells, a Keto (no carbohydrates) diet is the ONLY scenario that you should not use Anabolic-Pump.

Anabolic-Pump will possibly eliminate the need to Keto diet. If you incorporate carbohydrate re-feeds, you should incorporate Anabolic-Pump to take full advantage of muscle glycogen loading.

If you currently use keto plans, Anabolic-Pump may allow you to add certain carbohydrates as you get leaner. This will help you retain lean muscle and keep muscle glycogen stores full while shedding fat!

How about Carb-Cycling?


Carb cycling is alternating from high amounts of carbohydrates to low or no carbohydrates. USPLabs recommends using Anabolic-Pump when carbohydrate intake per meal is over 30 grams.

Anabolic-Pump can significantly enhance effects of carb-cycling by driving glucose into muscle cells while shuttling away from fat cells.

I only eat 20 grams of carbohydrates per meal. Should I use Anabolic-Pump?


The reason you are eating 20 grams of carbohydrates per meal is to lose fat and minimize glucose uptake in fat cells. Few people enjoy eating 20 grams of carbs per meal. They are sacrificing for the sale of body-recomposition. You live life drained, unfocused, and miserable! Training is a chore…yuck. I know because before Anabolic Pump, I needed to consume 20grams per meal to lose fat. I sacrificed hard earn muscle and dreaded the gym.

You can increase your carbohydrate consumption by 100% to 40 grams and lose more fat than the previous 20grams…while maintaining muscle. Your energy levels will sky rocket. Your gym hours become intensely productive. I recommend staying at 40 grams for a few weeks to gauge progress.

You can slowly increase your carbohydrates by 10 grams per meal and STILL lose fat. You will notice a new leaner physique in the mirror. With the addition of more carbohydrates, you been sparring amino acids and have been slowly increasing protein synthesis (new muscle). Again, I would keep carbohydrates at 50 grams for a few weeks to gauge progress.

I currently bulk at 200grams of carbohydrates, Should I increase carbohydrates?


No, you just need to implement Anabolic-Pump into your diet as recommended by the label. You should evaluate your diet for 2 weeks to gauge Anabolic-Pump's effects and then slowly add carbohydrates into your diet.

If you gain a slight amount of fat on 200grams of carbohydrates without Anabolic-Pump, you should fully expect to halt all fat gain and possibly burn fat. You need to find your sweet spot.

Should I add complex or simple carbs?


You should use complex carbohydrates like oatmeal, buckwheat, wheat pasta, sweet potato.

I currently use Simple sugars or fast digesting carbohydrates like Waxy maize starch and matlodextrin post workout (after a workout), should I eliminate these types of carbohydrates while using Anabolic-Pump?

No. Keep your post workout nutrition exactly the same for 2 weeks to gauge progress. After 2 weeks increase carbohydrate content by 10 grams and gauge progress for another 2 weeks and repeat the process until you find the sweet spot.

Can you provide a sample nutrition plan for when I bulk and when I cut?

This is incredibly difficult because every nutrition plan is user unique. In USPLabs style, we provide all the tools necessary to make the significant progress. USPLabs Representatives are experts in designing nutritional plans for Anabolic Pump and you can private message one or post a question in this thread. You can private message (Or post a question in this thread to) USPLabs Representative Dexterium and he will do diet construction, diet analysis and answer nutritional questions.

Can you give us a sample of your diet with Anabolic-Pump?


First, I make sure to drink over a gallon of water a day. A common complaint from Anabolic-Pump users is headaches. Anabolic-Pump significantly increases intracellular pools of muscle building glycogen. This phenomenon forces the body to use more water. PLEASE INCREASE your water intake..Super important!

My current goal is to gain muscle and lose fat. I weigh 230 lbs and stand 6’2” at about 15% bodyfat. My goal is to decrease Fat body mass down to 10% and increase muscle weight slowly. Before Anabolic-Pump, You could only accomplish this feat with steroids.

When Using anabolic Pump, you will begin to notice super recovery from exercise. Everyday, I wake up fresh and recovered so I decided to workout twice a day!

In the morning (8:30am) on an empty stomach, I perform 15 minutes of inclined treadmill at 4 mile per hour at a 5% incline. After the treadmill warm-up, I perform 15 minutes of a very light rotational axis routine that works miracles for back health that I learned from a brilliant expert named Jon Doyle (Baseball Training - Baseball Strength Training - Baseball Instruction) and then stretch for 10 minutes.

My main goal is fat loss and it’s really a rejuvenating/rehab workout that primes the system for the real workout later in the day.

In my car, I take 1 cap of Anabolic Pump (9:15 am) before the ride home.


Meal 1 at 9:30 am
60 grams oat meal
50 grams Protein (25 grams whey concentrate or isolate and 25 grams Micellar Casein)
3 grams fish oil
Multi vitamin

1 cap Anabolic Pump (12:15 pm)

Meal 2 (pre workout meal) at 12:30
50 grams protein (2 whole eggs 5 egg whites 25 grams micellar casein)
50 grams carbohydrates (2 pieces wheat toast and 1 cup of oat cereal)
10 grams of fat (8 from eggs yold and 2 from fish oil caps)

2:30 workout

1 cap Anabolic Pump 2:45 Pm

Meal 3 Post workout meal
60 grams oat meal
50 grams Protein (25 grams whey concentrate or isolate and 25 grams Micellar Casein)
3 grams fish oil
Multi vitamin

1 cap Anabolic Pump 5:30 pm

Meal 4 5:45 pm
50 grams protein (chicken breast or fish)
50 grams carbohydrates (brown rice)
10 grams of fat (8 grams from olive oil 2 grams from fish oils)
10 grams of broccoli

Meal 5 8:30 pm
50 gram protein (25 grams from cottage cheese 25 grams whey protein isolate)
5 grams pineapple (10 grams carbs)
5 grams flavorless fiber
3 grams fish oil

Repeat!
 
John Smeton

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Controlled Labs Orange Traiad has 100 mgs of ALA in it. This is an insulin miniker. Does 100 mgs of ala per day effect results while taking AP?
 
bpmartyr

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Controlled Labs Orange Traiad has 100 mgs of ALA in it. This is an insulin miniker. Does 100 mgs of ala per day effect results while taking AP?
I would just dose at separate times and there will be no worries.
 
DreamOfWeight

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dont mean to be a rookie but im really interested in stacking pslin powerfull and anabolic pump... how would u time theis supplements together.
 
Mulletsoldier

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dont mean to be a rookie but im really interested in stacking pslin powerfull and anabolic pump... how would u time theis supplements together.
15 minutes prior to breakfast:

1 AP


15 minutes before last meal before workout:

1 AP
3 PowerFULL

15 minutes prior to post-post workout meal:

1 AP

15 minutes prior to last meal of the day containing carbohydrates:

1 AP

45 minutes after last meal of the day:

2 PowerFULL
 
DreamOfWeight

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15 minutes prior to breakfast:

1 AP


15 minutes before last meal before workout:

1 AP
3 PowerFULL

15 minutes prior to post-post workout meal:

1 AP

15 minutes prior to last meal of the day containing carbohydrates:

1 AP

45 minutes after last meal of the day:

2 PowerFULL

thanks much appreciated
 

chongo25

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i work out around 830 average in the morning how do you suggest me taking anabolic pump cause it is kind of confusing taking it an hour before i workout cause of breakfast and then working out so soon so i just wait on taking another dose after the workout with my post workout meal and take the last dose in mid day?
 
dexterium

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i work out around 830 average in the morning how do you suggest me taking anabolic pump cause it is kind of confusing taking it an hour before i workout cause of breakfast and then working out so soon so i just wait on taking another dose after the workout with my post workout meal and take the last dose in mid day?
It is optimal if you do the following:

6:30 AM - Wake and take Anabolic Pump

6:45 AM - Eat a meal containing 60 g of complex carbohydrates and ~30 g of protein.

8:30 AM - Workout

If you want further help, just PM me! Thanks!
 

AM07

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So if one were cutting, it's okay to use AP, correct? I would dose it three times per day, once in the morning, once in the afternoon, and once at night for 30 days. Does dosing it at night have any effect on sleep?

Is 40 grams enough at AP sittings? I would like to consume about 200 grams of protein per day.

Would running clen have any adverse effects on the AP?
 
bpmartyr

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So if one were cutting, it's okay to use AP, correct? I would dose it three times per day, once in the morning, once in the afternoon, and once at night for 30 days. Does dosing it at night have any effect on sleep?

Is 40 grams enough at AP sittings? I would like to consume about 200 grams of protein per day.

Would running clen have any adverse effects on the AP?
Yes.
No.
Yes.
No.

Great addition to cutting. Doesn't effect sleep. 40 grams is fine. Clen will not hurt the AP as far as I know; I would be more concerned with my heart personally.
 

AM07

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Ok, thanks. I'm going to start the AP tomorrow and run it for 30 days, then jump into an 8-week Jungle Warfare stack. Should be fun!
 

AM07

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Also, would adding Lean Xtreme to AP help in terms of fat loss?
 
Mulletsoldier

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It would not hurt, no. I'm unsure of the particular dosages with LX, but as far as I know the formula should not conflict in any major way.
 

AM07

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How long does it take to start feeling the effects of AP? I've taken two today and haven't felt the "pump" yet, but today is only my first day with this compound. I will dose once more, tonight before dinner, which will consist of brown rice and beef stew.
 
Mulletsoldier

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It all depends on individual body chemistry; mostly, do not be afraid to stray from bottle recommended dosages and timing. AP is a supplement of timing and experimentation. Also, begin with the carbohydrate sources you have reacted most favorably to historically. This will ensure you're adapting properly.
 

AM07

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Not sure of which CHO I react to most favorably, I guess maybe oats? I'll try that tomorrow for breakfast.

As for dosages, I'm going to keep it at 3 caps/day because I want this to last 30 days. I hope the effects start to kick in at least this week. I will keep you guys updated and probably ask more questions in the next couple days :)

As for timing, is 15 minutes the typical time to wait before eating a CHO-rich meal? Also, if I only have about 200 grams of CHO a day, should I still get the benefits from AP, as long as the majority of those CHO are being taken with my AP meals?
 

AM07

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End of the second day, and still don't feel anything from the AP. Maybe I just don't respond to it?
 
dexterium

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As for timing, is 15 minutes the typical time to wait before eating a CHO-rich meal? Also, if I only have about 200 grams of CHO a day, should I still get the benefits from AP, as long as the majority of those CHO are being taken with my AP meals?
Yes, 15 minutes is the typical time to wait before eating a CHO-rich meal. Yes, you should still be getting the benefits from AP as long as the majority of your CHO are being taken with the AP meals.
 
dexterium

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End of the second day, and still don't feel anything from the AP. Maybe I just don't respond to it?
You will probably have to wait for more than 2 days to feel it. Give it a few more days.
 
Mulletsoldier

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Not sure of which CHO I react to most favorably, I guess maybe oats? I'll try that tomorrow for breakfast.

As for dosages, I'm going to keep it at 3 caps/day because I want this to last 30 days. I hope the effects start to kick in at least this week. I will keep you guys updated and probably ask more questions in the next couple days :)

As for timing, is 15 minutes the typical time to wait before eating a CHO-rich meal? Also, if I only have about 200 grams of CHO a day, should I still get the benefits from AP, as long as the majority of those CHO are being taken with my AP meals?
Begin with 15 minutes, and gauge your response from there. You may need more or less time for the Anabolic Pump to take effect; as I said, Anabolic Pump is a supplement of learning and experimentation - once you find that 'sweet spot', it is quite effective.
 

AM07

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You will probably have to wait for more than 2 days to feel it. Give it a few more days.
Word, someone was telling me it varies for different people and it took him a week to start really feeling it.
 
ono

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hmm sounds like an awesome product. Just a bit concerned about the possible mental confusion it can cause if you don't stick to the recommended dosage and timings. What causes this? It's sounds like a fun side effect to have :woohoo:
 

hawks31

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just a few things i want to double check before i buy this product. ive researchde it a bunch but sometimes i need direct answers from people. so basically any kind of cutting diet without carbs wont work with AP? and will AP work well with Leviathan Reloaded?
 
ono

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hmm sounds like an awesome product. Just a bit concerned about the possible mental confusion it can cause if you don't stick to the recommended dosage and timings. What causes this? It's sounds like a fun side effect to have :woohoo:
Aha it's probably just hypoglacemia or however you spell it. That shizzle is no fun. Suppose it will be ok if i carb up when am on it....which is what i'll be doing
 
dexterium

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hmm sounds like an awesome product. Just a bit concerned about the possible mental confusion it can cause if you don't stick to the recommended dosage and timings. What causes this? It's sounds like a fun side effect to have :woohoo:
This is caused by your blood sugar levels dropping too low aka hypoglycemia. It is not a fun side effect at all, actually lol
 
dexterium

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just a few things i want to double check before i buy this product. ive researchde it a bunch but sometimes i need direct answers from people. so basically any kind of cutting diet without carbs wont work with AP? and will AP work well with Leviathan Reloaded?
You need carbohydrates with Anabolic Pump in order for it to work.

AP would work with Leviathan Reloaded but make sure that you take them at the same time.
 

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alright great Dex. and thanks for the that huge list of foods that would be alright for me to eat while on these 2 supps. but im a little curious as to why it's best to take the AP and the LR at the same times during the day.?
 
ono

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This is caused by your blood sugar levels dropping too low aka hypoglycemia. It is not a fun side effect at all, actually lol
Haha i realised it's probably that. And yeah it's happened to me quite a few times before. It's horrible.
 
Cool

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What if I'm injured and can't lift for a week or 2? Should I continue AP?
 

sw bill

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Can AP be takin while on PCT? I just finished a 4 week cycle of Methyl1D and now am taking Formadrol and Psarm for a PCT.
I have a bottle of AP but should i wait until after PCT to start on it?
I posted this in the PCT section a few days ago and got no responce,Hope i have better luck here. Thanks

BTW, I plan on bulking at least 2 more months before cutting if that makes a difference.
 
Mulletsoldier

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I think AP is a great supplement in an environment attempting to reboot one's HPTA. Not only due to its GLUT4 translocation, but also its anti-lipogenic and anti-cholesterolemic functions.
 

KrazyLegs

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Does it work well with a stack of RPM/Drive or should I wait to dose AP on its own?
 

AM07

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11th day, not noticing anything. I've tried waiting different times, anywhere from 10-75 minutes. I've tried various amounts of complex carbs, anywhere from 35-70 grams, still nothing.

Anything else I can do to hopefully feel the effects of this supplement?
 
Force of Green

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Aha it's probably just hypoglacemia or however you spell it. That shizzle is no fun. Suppose it will be ok if i carb up when am on it....which is what i'll be doing
You clarified your own confusion just now! Bravo.
 
dexterium

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11th day, not noticing anything. I've tried waiting different times, anywhere from 10-75 minutes. I've tried various amounts of complex carbs, anywhere from 35-70 grams, still nothing.

Anything else I can do to hopefully feel the effects of this supplement?
Have you tried any simple carbs?
 

AM07

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Have you tried any simple carbs?
Nope. But if it requires using simple carbs, then I see no reason taking the supplement in the first place since I don't consume simple carbs, and none of us should be if our goals are what we say they are.
 
bpmartyr

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Nope. But if it requires using simple carbs, then I see no reason taking the supplement in the first place since I don't consume simple carbs, and none of us should be if our goals are what we say they are.
Even if the supplement negates any negatives associated with said simple carb? You will avoid insulin spikes, insulin resistance and weight gain that accompany them when precipitated by AP.

I am a no sugars advocate myself ... well, I was before trying them with AP. FWIW
 
Force of Green

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I picked up a couple bottles each of P-Slin and AP... DAMN! Amazing stuff! I had a really nice run with it before and wasn't afraid to abide by and trust the instructions that say : (P-Slin) "Use 60-100 grams of carbs" & (AP) "Use atleast 40 grams of complex carbs"... whatever... outstanding results manifested themselves from the first dose of each! No exaggeration!
 
Mulletsoldier

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Nope. But if it requires using simple carbs, then I see no reason taking the supplement in the first place since I don't consume simple carbs, and none of us should be if our goals are what we say they are.
It does not require simple carbohydrates, but Dex was merely suggesting you may respond better with a mixture; this could be due to your insulin sensitivity predisposition.
 

corsaking

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Before I spend almost £40 on this product will someone please explain how Phellodendron the first ingredient, works in this formula .I have searched Google and despite the claim that only USP had heard of this plant/herb ,lots of information is available through Google, quote from one-Phellodendron has been used to treat gastric ulcers, bacterial infections, fungal infections, and diabetes. It has also been used for immunosuppression and as a topical anti-inflammatory agent.

I have no wish to knock this product as anecdotal feedback seems to be good, but if we are trying to create an anabolic window throughout the day , why not eat every 2/3 hours slow release carbs along with good quality protein.This will create an insulin rise ,and shuttle gradually nutrients into the bloodstream , but not a spike as in after training when its wanted.

For me personally supplement companies have to do a lot more hard work and research to convince me to buy their product. So many supplements contain herbs which have been used in folklore medicine for years and for something not related to bodybuilding. As soon as it gets into the bodybuilding arena , for some reason its the icing on the cake to getting the "physique of your dreams!"

So back to where I came in , can someone come up with information that will convince me to buy this product .I am not taken in by advertising claims .
 

AM07

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It does not require simple carbohydrates, but Dex was merely suggesting you may respond better with a mixture; this could be due to your insulin sensitivity predisposition.
But the thing is, with my diet, there is nothing that includes simple carbohydrates. I don't even consume a PWO shake; I just come home and typically eat a full meal containing complex carbohydrates and lean meat.

So should I take an AP right after my workout, then try having a PWO shake consisting of 50 grams dextrose with 35 grams whey 20 minutes later?

I don't understand how insulin sensitivity (specifically mine, which I doubt could be figured out just by the feel of things after I eat something) could have anything to do with this if I've tried eating at various times after taking the AP. So is it better if one has a higher insulin sensitivity (better for overall health) with this product than a lower sensitivity? Do the non-responders of this product tend to have a high insulin sensitivity?
 

corsaking

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If you want to increase your own insulin sensitivity see what L.REA has to say about doing just that in his book "Building the perfect beast -naturally "


Before spending money on a product which may or may not work .After youve read what he has to say on insulin, then decide what you want to do
 
bpmartyr

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I believe the non-responders may have a higher resistance yes. AP often requires time to increase your sensitivity to insulin before it's full effects are realized. The increased glut4 creates an environment where less insulin is required thus less insulin is released. Over time the decreased levels increase sensitivity. For overall health this is a very good thing as even a cursory exposition to the effect of insulin will reveal it's intrinsically toxic nature.
 

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So do you think I may not be responding because my insulin sensitivity is high or low?
 
bpmartyr

bpmartyr

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So do you think I may not be responding because my insulin sensitivity is high or low?
I can only speculate, but you may have some resistance or "low sensitivity". I would suggest continuing using it with your existing diet and see if you start to notice some effects by the end of the bottle. Even if you are not "feeling" anything, the process I described above regarding the glut-4 translocation and reduced insulin release should indeed still be taking place if dosing as prescribed and that is reason enough for me to continue taking it.

Really, the overall health benefits of AP make any "pump", accelerated muscle gain or fatloss effects take second stage in my book.
 
Mulletsoldier

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Before I spend almost £40 on this product will someone please explain how Phellodendron the first ingredient, works in this formula .I have searched Google and despite the claim that only USP had heard of this plant/herb ,lots of information is available through Google, quote from one-Phellodendron has been used to treat gastric ulcers, bacterial infections, fungal infections, and diabetes. It has also been used for immunosuppression and as a topical anti-inflammatory agent.

I have no wish to knock this product as anecdotal feedback seems to be good, but if we are trying to create an anabolic window throughout the day , why not eat every 2/3 hours slow release carbs along with good quality protein.This will create an insulin rise ,and shuttle gradually nutrients into the bloodstream , but not a spike as in after training when its wanted.

For me personally supplement companies have to do a lot more hard work and research to convince me to buy their product. So many supplements contain herbs which have been used in folklore medicine for years and for something not related to bodybuilding. As soon as it gets into the bodybuilding arena , for some reason its the icing on the cake to getting the "physique of your dreams!"

So back to where I came in , can someone come up with information that will convince me to buy this product .I am not taken in by advertising claims .
Phellodendron has been shown to mitigate AMPk. AMPk is immediately involved in the glycogen uptake pathway via induction of GLUT4; especially in terms of contractile tissue. GLUT4 mRNA expression and translocation can be adversely affected by the downregulation of AMPk and other kinases.

Evidence:

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Yun S. Lee1

Berberine has been shown to have antidiabetic properties, although its mode of action is not known. Here, we have investigated the metabolic effects of berberine in two animal models of insulin resistance and in insulin-responsive cell lines. Berberine reduced body weight and caused a significant improvement in glucose tolerance without altering food intake in db/db mice. Similarly, berberine reduced body weight and plasma triglycerides and improved insulin action in high-fat–fed Wistar rats. Berberine downregulated the expression of genes involved in lipogenesis and upregulated those involved in energy expenditure in adipose tissue and muscle. Berberine treatment resulted in increased AMP-activated protein kinase (AMPK) activity in 3T3-L1 adipocytes and L6 myotubes, increased GLUT4 translocation in L6 cells in a phosphatidylinositol 3' kinase–independent manner, and reduced lipid accumulation in 3T3-L1 adipocytes. These findings suggest that berberine displays beneficial effects in the treatment of diabetes and obesity at least in part via stimulation of AMPK activity.
As stated, this study explains Berberine's ability to regulate energy expenditure as a whole - rather than simply glucose metabolism - in both myocytes and adipocytes. Further, it inhibited both differentiation and hypertrophy in accumulated lipids, most likely regulating the PPAR family. In terms of the AP-specific glucose effect, it lead to increased levels of GLUT4 in myocytes specifically.

Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK

Zhe Cheng, Tao Pang, Min Gu, An-Hui Gao, Chuan-Ming Xie, Jing-Ya Li, Fa-Jun Nan and Jia Li

National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, P. R. China


Received 17 May 2006; revised 13 September 2006; accepted 13 September 2006. Available online 20 September 2006.

Abstract

Berberine is a plant alkaloid used in traditional Chinese medicine and has been reported to have antihyperglycemic activity in NIDDM patients. However, the molecular basis for this action is yet to be elucidated. Here we investigate the effects and signaling pathways of berberine on L6 rat skeletal muscles. Our study demonstrates that berberine stimulates glucose uptake in a time- and dose-dependent manner. Intriguingly, berberine-stimulated glucose uptake does not vary as insulin concentration increases, and could not be blocked by the PI 3-kinase inhibitor wortmannin. Berberine only weakly stimulates the phosphorylation of Akt/PKB, a key molecule in the insulin signaling pathway, but strongly promotes the phosphorylation of AMPK and p38 MAPK. The effects of berberine are not a result of pro-oxidant action, but a consequence of an increased cellular AMP:ATP ratio. Moreover, berberine-stimulated glucose uptake is inhibited by the AMPK inhibitor Compound C and the p38 MAPK inhibitor SB202190. Inhibition of AMPK reduces p38 MAPK phosphorylation, suggesting that AMPK lies upstream of p38 MAPK. These results suggest that berberine circumvents insulin signaling pathways and stimulates glucose uptake through the AMP-AMPK-p38 MAPK pathway, which may account for the antihyperglycemic effects of this drug.
As stated above, AMPk regulates glucose metabolism through insulin-reactive, though not necessarily insulin-dependent, pathways. It has a weak affinity for Akt/PKB which are IR-dependent compounds, whereas both studies show a direct induction of AMPk/p38 MAPK, which are more or less GLUT4 specific kinases. This all leads to lower serum levels of insulin via increased glycogen storage while circumventing insulin's action.

Lagerstroemia (extracted for both Corosolic and Tannic Acid) works in a corollary manner - creating positive energy turnover ratios between adipocytes and myocytes.
 
Mulletsoldier

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So do you think I may not be responding because my insulin sensitivity is high or low?
It could very well be either. If you are sensitive to the action of insulin already, than the insulin-reactive pathways AP is mitigating will not see immediate benefit; similarly, if you have been insensitive to the action of insulin, AP may take some time to affect the above mentioned kinases.

How long have you been using the product?
 
Force of Green

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I believe the non-responders may have a higher resistance yes. AP often requires time to increase your sensitivity to insulin before it's full effects are realized. The increased glut4 creates an environment where less insulin is required thus less insulin is released. Over time the decreased levels increase sensitivity. For overall health this is a very good thing as even a cursory exposition to the effect of insulin will reveal it's intrinsically toxic nature.
I saw results immediately... I pretty much already had the carbohydrate content already setup in a configuration that's optimal for AP and P-Slin. Now, all I had to do was dose it 15 minutes before hand. I'm amazed.
 

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