MuscleGuyinNY
Banned
Am I missing something?
I was going to say well maybe thats cause it isn't.Looks like it obvisouly is though.You gona use it?17-HD doesn't mention that it's methylated either.
Author L. Rea said:Is it 17a-methyl-5a-dehydro-etiocholane-4,6-dien-3-one-17-ol and in a red bottle? If so we did the label correction coming on 2 years ago. This is simply the 17a methyl analog of 17b-hydroxy-androsta-4,6-dien-3-one that started so much contraversy about a year or more ago. The issue was "is it an androgen or an AI?". Well, both as is teslac, aromasin ATD and most other AIs. However it sucks as a serious anabolic as even n higher dosages it fails to show up in total testosterone as an AAS should. Patrick Arnold and I do not agree that a methyl bond at 17a still allows for AI activity. Though I usually agree with PA this would be to say that Masterone has no AI value and that the lower estrogen levels blood work has shown durring testing were wrong as well. It also would mean that several journals and patent applications are in error. So is it an AI?
Well, hell yes...
A synopsis of the anti-aromatase (anti-estrogenic) capacity of 17b-hydroxy-androsta-4,6-dien-3-one and its preferential nature in this capacity over other agents
17b-hydroxy-androsta-4,6-dien-3-one is an anti-aromatase in the family of other ‘6-delta’ androstenes. The addition of a 6-delta (6-ene) group allows for any androstene to become predominantly anti-estrogenic by creating a compound that now potently induces anti-aromatase activity. In this family 3,17-diones (ie., androsta-1,4,6-trien-3,17-dione, androsta-4,6-dien-3,17-dione) are the most potent anti-aromatase agents in regard to the effect of the 3 and 17 position functional groups on activity. However, these agents appear to have a disposition to induce unwanted side effects which include gynecomastia. It has been found that 17-hydroxy-3-one agents still display a sound potent anti-aromatase capacity (though of a slightly lower potency than 3,17-diones), but do not appear to have any predisposition to unwanted negative side effects, particularly the highly unwanted potential for gynecomastia. Overall they are the preferred agents to allow the body to have optimized estrogen modulation without undesirable drawbacks. The 4,6-dien is preferred over the 1,4,6-trien analogue as simply it is superior still in overall cost effectiveness and thus the most superior commercial agent for the purpose of positive estrogen modulation.
Documentation that expounds on the nature of 17b-hydroxy-androsta-4,6-dien-3-one as well as related agents as an aromatase inhibitor (AI) can be found in the below reference:
A Schering patent that cites the compound as an AI and the reference it is within:
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(excerpt)
For the purposes of this invention, aromatase inhibitors are all those compounds that prevent estrogens from being formed from their metabolic precursors by inhibiting the enzyme aromatase (inhibition of biosynthesis). As aromatase inhibitors, therefore, all compounds are suitable that are suitable as substrates for aromatase, such as, for example, the testolactone (17a-oxa-D-homoandrost-1,4-diene-3,17-dione) that is described in the "Journal of Clinical Endocrinology and Metabolism," 49, 672 (1979); the compounds that are described in "Endocrinology " 1973, Vol. 92, No. 3, page 874:
androsta-4,6-diene-3,17-dione,
androsta-4,6-dien-17beta-ol-3-one acetate,
androsta-1,4,6-triene-3,17-dione,
4-androstene-19-chloro-3,17-dione,
4-androstene-3,6,17-trione;
Again all androstene compounds will have a predominantly AI capacity if the 6-position is altered. Such alterations include the abovementioned 6-delta alteration, the commonly known 6-oxo alteration, as well as many others including alkylations, brominations, et. al. While 17-one compounds in this class have a higher AI potency they are unfavorable due to their inherent predisposition to cause unwanted effects. The 17-hydroxy variants are superior overall as to their strong AI potency that while slightly below 17-one agents do not have the potential for unwanted side effects found with their 17-one counterparts.
Make sense why we still believe in Jungle Warfare after all the bashing by other company reps? We have good research to support this but naturaly some idiot will call it otherwise.
Plz see below:
...here's a thread about this too: http://anabolicminds.com/forum/l-r-i/63651-jungle-warfare-what.html
imo staythe **** away from JW. it gave me NO gains, terrible headaches, bad libido crash, bad joints, and hair loss... not to mention GI discomphort and bizzare ass dreams.
yes.Safe to stack with Epi then?
imo staythe **** away from JW. it gave me NO gains, terrible headaches, bad libido crash, bad joints, and hair loss... not to mention GI discomphort and bizzare ass dreams.
yes.
I've used it back in the day. It's prob. the best pre-workout stim I've ever taken. Ups strength, mood, etc.. It's pretty nice..Ok, I see nutra sells Vyotech 17-HD. I'll try it sometime.
I've used it back in the day. It's prob. the best pre-workout stim I've ever taken. Ups strength, mood, etc.. It's pretty nice..
I did use the IDS version though.. But, they're supposed to be the same. Oh, and I believe that it works best on an empty stomach, in fact, I'm nearly certain.
IDS's isn't methylated.I think I heard one say it's at twice of 17-HD's doses.Although it seems most like 17-HD better.Prob cause of the methylation.
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I will explain how this product bothers me on an unparalleled scale. It is what is wrong with the industry. Shawn Ray uses it…hmm. This product is deceptive, trying to sound like a prohormone or even a potent steroid. The company has stated they did not decide on the name or try and be deceptive it was what the “scientist” (seriously) named it...so that's what they went with...HAHAHA! Even if they have a "scientist" of some sort, which they probably don't, that guy is not in control of their financial fate in the naming/marketing/advertising of the product.
17-HD (17-Halo-Methyl-Dianadrone): To review the choice of name here, by marketing NOT SCIENCE…let’s review.
1.)17 – As is c17a, the 17th carbon at the alpha position is where anabolic steroids have their potency and toxicity and often is where a methyl group is as attached.
2.)Halo – Besides being a great X-Box game, it is another group of steroids such as the popular halotestin, also halodrol is quite popular in the prohormone world.
3.)Methyl – See #1. Also – see buzz word of the year (#2 is ethyl ester)
4.)Dianadrone – Diana(bol) aka methandrostenolone, comes pretty close to hitting the whole 17-HD name is one fall swoop.
5.)17-HD, or 17-Halo-Methyl-Dianadrone, sounds like a chemical compound doesn’t it? Sounds like one heck of a methylated potent oral steroid. Right?
Guess what? It’s not. Matter of fact it’s just a bunch of herbs. I’d say this is pretty deceptive so far, but lets get into the useless or even counterproductive part.
Here is the ingredients according to the write-up:
17- Halo-Methyl-Dianadrone: 400mg
Ge Gan (pueraria lobota)
Smilax Officinalis
N.O. Oliliacae
Betaecdysterone 100mg
Wild yam extract 100mg
Glabra 100mg
Phosphatidyl choline 50mg
Citric acid 50mg
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We'll start with wild yam and go from there.
Wild Yam is great at regulating estrogen...there's a potent benefit! And I will quote:
"Wild yam has been used for menstrual cramps or pain, menopausal symptoms, rheumatic conditions, and gallbladder complaints. Wild yam is sometimes suggested as an alternative to hormone replacement therapy. While components of wild yam are chemically manufactured into the hormones progesterone or estrogen, the body is unable to use wild yam in the same way."
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Ge Gen is aka kudzu and I quote:
"Chemicals extracted from kudzu include isoflavones known as daidzein, daidzin, genistein, and puerarin. Isoflavones are plant chemicals that have estrogenic and antioxidant effects."
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How 'bout Smilax? Let's go for the trifecta shall we? Smilax officinalis is also known as sarsparilla.
I'll quote again...
"In the United States, sarsaparilla is sold primarily as an oral remedy for skin conditions such as psoriasis. It is believed that chemicals in sarsaparilla may attach to endotoxins (the remnants of bacterial cells) that are common in individuals with psoriasis and certain other conditions. By eliminating or reducing the amounts of endotoxins in the body, sarsaparilla may help to relieve the condition.
Orally, sarsaparilla also has weak diuretic and laxative effects, which may make it useful in promoting the loss of excess water from the body and also in treating mild constipation. It may also promote sweating, which may help to reduce fever. Additionally, sarsaparilla contains chemicals that may act as a mild expectorant – a substance that may loosen bronchial mucus and promote coughing. However, none of these effects has been verified through clinical studies and they may vary greatly depending on the amounts and type of sarsaparilla that is used. "
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Hmm...well we've established it raises estrogen, has laxative effects...is there anything else this miracle supplement can do for me you ask?
Well I am glad you asked...Glabra is cute renaming (as every ingredient is and the product itself) of Glycyrrhiza glabra, aka Licorice. Licorice you say? Yes, THE ultimate bodybuilding supplement. And I will quote:
"Licorice is also a mild laxative. Large doses of glycyrrhizinic acid and glycyrrhetinic acid in liquorice extract can lead to hypokalemia and serious increases in blood pressure, a syndrome known as apparent mineralocorticoid excess. These side effects stem from the inhibition of the enzyme 11β-hydroxysteroid dehydrogenase (type 2) and subsequent increase in activity of cortisol on the kidney. 11β-hydroxysteroid dehydrogenase normally inactivates cortisol in the kidney; thus, licorice's inactivation of this enzyme makes the concentration of cortisol appear to increase. Cortisol acts at the same receptor as the hormone aldosterone in the kidney; thus, the effects mimic aldosterone excess, although aldosterone remains low or normal during licorice overdose. Cortisol does not actually increase either; however, its activity in the kidney effectively increases due to the disabling of this enzyme. To decrease the chances of these serious side effects, deglycyrrhizinated licorice (DGL) preparations are available.
Licorice affects the body's endocrine system. It can lower the amount of serum testosterone, but whether it affects the amount of free testosterone is unclear. A PubMed search for licorice AND testosterone will provide additional information."
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Well, cool, Licorice decrease testosterone, increases blood pressure and may increase catabolic hormones. Oh yeah, and again its a laxative.
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So lets tally up the results: we got elevated estrogen, decreased testosterone, increased cortisol, increased blood pressure, and 2 laxatives.
Lastly, there is one ingredient listed that, in fact, does not exist…so I can’t tell you what it is other than it is an herb. N.O. (sounds like Nitric Oxide – Buzz Word!) Olilicae. Sorry. Given the collective data one WHAT IS IN THERE, I wouldn’t hope for much.
Well the only thing of benefit I see here is the 50mg of Vitamin C (citric acid), which doesn't even meet the lowly RDA. Sweet formulation. Really.
Good luck to anyone who uses this. The supplement industry loves you.
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Shawn Wells, MPH, RD, CISSN
Chief Clinical Dietitian
Certified Sports Nutritionist
I hate to break the news to you, but...............
You hate to break what to me?
Did you not read the entire post about 17-HD?:frustrate
I think slow-mun was pointing more towards the fact that it's not actually methylated.Yeah I read it.Many like the supplement alot.The guy at the supplement store who has straight up told me not to buy a supplement a couple of times,and also told me it's pointless to stack an energy/creatine/pump supp with creatine,told me that it has been there for years,and it is still probably his favorite supplement they carry.I wasn't asking about it,or asking about a type of supplement.He just told me it's what he uses when he cuts cause it makes cardio so much easier.To be exact,I asked him if he stays lean or if he actually cuts.Many say they love the energy it gives you.Theirs one in this thread!
I think slow-mun was pointing more towards the fact that it's not actually methylated.
Well thats why I asked "you hate to break what to me?"I didn't see what he was breaking to me.I seen them dis the supplement,but many like it.Some things serve as other purposes and have synergy affects when combined.If thats what he meant,he should of said "it's not methylated."Thats what I would of said anyways.
I'm pointing out the fact that its basically a worthless supplement and did so by posting an article by one of the formulators at MAN. If you think its a good supplement then more power to ya. I'm not going to get into a pissing match with you, b/c it will do me no good. Next time I'll just post 17-HD=UNMETHYLATED, HERBAL, GARBAGE.
I have atually never used it.I used IDS's version and got a great rush the first time I took it.I'm just pointing out that many do like it,not all,but many.Thats how all supplements are though.I did research it and thats what I concluded from people who actually used it.Never heard anything positive or negative about increasing test,but most love the energy from it.
I've used it as well and had an energy rush that went away with consistent usage. Its not worth the price IMHO. IDS's version is, but the product is still of questionable worth. If people really want a preworkout boost, then things like RPM and R4W are much better options. I'm telling you this, b/c I have wasted a sh!t ton on products that were worthless. I sometimes come off as a d!ck, but I'm trying to save people money.
I'm wanting to try RPM.I have two bottles of drive to use with nolva after m drol.I am going to try hemadraulix aventually.Prob once I run out of xlevol.I absolutely love xlevol!I don't feel wired or edgy,but once I start lifting,i'm ready to go!I didn't like R4W though.I still have most of the bottle sitting in my cupboard.I'm only looking for something else to cycle with the xlevol,instead of using it all the time.
I usually use Hemodraulix, b/c I'm addicted to morning coffee. Stimulant containing preworkout suppplements are usually to much for me if taken to close to the morning. I actually liked R4W better than RPM, but that's just me. I'm anxious to try the new formula of R4W, it looks very good.
riseboi's blood tests are missing.
I really wouldn't be worried about liver enzymes. I don't understand everyone's weird obsession with liver and liver enzymes.
I think I've had the highest liver enzymes out of everyone on this board.
My ALT/AST were well over 500.
They went down. I got multiple bloodwork over it. It is no big deal.
People need to be more worried about their lipid levels.
I'm concerned about my lipid levels and especially my libido.
That's why I've been asking a lot about JW.
This is just my own personal opinion:
If you are going to use Jungle Warfare, you might as well just run H-Drol instead. They will probably do equal damage to your body (just my own guess), but you'll come out ahead more with H-Drol and at least you know what is in H-Drol.
From general feedback, JW seems like sides in a bottle (not to mention more expensive than H-Drol).