I've taken lean xtreme 2.0 before. Joints got pretty sore at 4 caps a day but some bulk cissus took care of that. I haven't noticed any libido prolems or cortisol rebound either.
I never really get sore joints from it oddly, but I do have suspicions that going on and off anti-corts or even DHEA might have an impact on the immune system. I used both DHEA and anti-corts this winter and I have been sick more times than ever before. Could easily be pure coincidence but there is a lot interaction with the immune system with these products and I suspect if you stop them cold turkey like I did, it might leave you hangin so to speak.