NAC reduces urge to gamble.
- Thread starter reidhoch
- Start date
CryingEmo
Well-known member
That's a good idea for a supplement.
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Irish Cannon
Legend
I'd buy it.
Rogue Drone
Well-known member
Here's the Mechanics - NAC stimulates Glutamate, which stimulates Dopamine, the reward chemical, both directly and by reducing GABA.
By itself, NAC won't cure addictions (Gambling/Nicotine/Stims/Sex, etc.) but it's a good addition to further the effects of a Dopamine/NE Treatment Protocol.
NAC has a half life of 6.25 hours, dose at 0.6 gms or more, 3 -4X Daily.
This is a part, a small part, of how I got my brother in law off Meth, successfully, so far, after 3 months back in the Temptation World - Wellbutrin and Deprenyl and Modafinil and NAC and L-Phenyl 10 days beforehand for a baseline buildup, then he and I in a cabin in Montana,(Northern Garfield County) toughing it out with day hikes for 16 days on Coffee and Syntrax Nectar and Maltodextrin, and putting his manic ass to sleep with a half speed palm heel strike/push, Xanax and double shots of Jim Beam.
Tough Love, the Chemical Adapt and Nature Way.
I could have sliced him,tempted I was at times, left him to odor for Griz to chow on - Call me Humane, he never was aware that I was ranging back on one that was sloppy trailing our six on most days out and looking for a lazy meal.
By itself, NAC won't cure addictions (Gambling/Nicotine/Stims/Sex, etc.) but it's a good addition to further the effects of a Dopamine/NE Treatment Protocol.
NAC has a half life of 6.25 hours, dose at 0.6 gms or more, 3 -4X Daily.
This is a part, a small part, of how I got my brother in law off Meth, successfully, so far, after 3 months back in the Temptation World - Wellbutrin and Deprenyl and Modafinil and NAC and L-Phenyl 10 days beforehand for a baseline buildup, then he and I in a cabin in Montana,(Northern Garfield County) toughing it out with day hikes for 16 days on Coffee and Syntrax Nectar and Maltodextrin, and putting his manic ass to sleep with a half speed palm heel strike/push, Xanax and double shots of Jim Beam.
Tough Love, the Chemical Adapt and Nature Way.
I could have sliced him,tempted I was at times, left him to odor for Griz to chow on - Call me Humane, he never was aware that I was ranging back on one that was sloppy trailing our six on most days out and looking for a lazy meal.
yeahright
Well-known member
Slightly different version of the article:
September 17, 2007
Don't gamble with NAC
The September 15, 2007 issue of the journal Biological Psychiatry published the results of a pilot study conducted by Jon E. Grant, MD and colleagues at the University of Minnesota, Minneapolis that consuming the amino acid N-acetyl cysteine (NAC) reduces the urge to gamble in individuals with gambling addictions, and may help reduce other addictions.
Fifteen men and twelve women treated for pathological gambling as determined by the Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS) were given increasing doses of N-acetyl cysteine for eight weeks. At the end of the treatment period, average test scores had improved, with 16 of the participants classified as responders to the therapy. While three of the responders did not wish to risk discontinuing NAC, 13 entered a double-blind phase of the research, in which one group of subjects received N-acetyl-cysteine and the remainder received a placebo for six weeks. Eighty-three percent of those who received NAC responded favorably, compared with only 28.6 of those assigned to the placebo.
N-acetyl cysteine's effect on glutamate, which is frequently associated in the brain with reward, is likely to be the amino acid's mechanism of action in helping to control addiction. Similar studies with NAC have found positive effects against drug addictions in animals.
“It looks very promising,” stated Dr Grant, who is an associate professor of psychiatry at the University of Minnesota School of Medicine. “We were able to reduce people’s urges to gamble.”
Dr Grant is currently investigating NAC in methamphetamine users. “This research could be encouraging for a lot of addictions,” he said.
September 17, 2007
Don't gamble with NAC
The September 15, 2007 issue of the journal Biological Psychiatry published the results of a pilot study conducted by Jon E. Grant, MD and colleagues at the University of Minnesota, Minneapolis that consuming the amino acid N-acetyl cysteine (NAC) reduces the urge to gamble in individuals with gambling addictions, and may help reduce other addictions.
Fifteen men and twelve women treated for pathological gambling as determined by the Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS) were given increasing doses of N-acetyl cysteine for eight weeks. At the end of the treatment period, average test scores had improved, with 16 of the participants classified as responders to the therapy. While three of the responders did not wish to risk discontinuing NAC, 13 entered a double-blind phase of the research, in which one group of subjects received N-acetyl-cysteine and the remainder received a placebo for six weeks. Eighty-three percent of those who received NAC responded favorably, compared with only 28.6 of those assigned to the placebo.
N-acetyl cysteine's effect on glutamate, which is frequently associated in the brain with reward, is likely to be the amino acid's mechanism of action in helping to control addiction. Similar studies with NAC have found positive effects against drug addictions in animals.
“It looks very promising,” stated Dr Grant, who is an associate professor of psychiatry at the University of Minnesota School of Medicine. “We were able to reduce people’s urges to gamble.”
Dr Grant is currently investigating NAC in methamphetamine users. “This research could be encouraging for a lot of addictions,” he said.
Redeemer
Member
That is interesting, but I think the health benefits, especially when using it to mitigate against damage from exogenous compounds outweigh the potential risk.
yeahright
Well-known member
Now that's interesting. Something to think about.
poison
Board Sponsor
size
Well-known member
This is really interesting and something that I have never heard of. I would like to know what the dosages administered where.
NAC has done nothing to curb my gambling appetite.
g29er
Member
Very interesting!! Ive also heard that it reduces cocaine cravings. If it reduces the urge to gamble,I should probably take it before I go to Vegas next month.
g29er
Member
Nothing puts me to sleep like a half-speed palm heel strike. Chamomile tea is for wussies.