I am curious if anyone complaining about withdrawal effects fromwere taking larger than recommended doses. I spoke to a very knowledgeable doctor regarding and rebound hypertension at 500 mg to 1,500 mgs seems doubtful. in the recommended dosage range should have very little impact on bp. My guess is someone having 7 days of withdrawal and severe rebound hypertension where taking some pretty hefty doses. I have read reports of people using as high as 12 grams at a single usage. The problem with again is that people with propensities to abuse drugs or alcohol should shy away from because those are the type that may start taking this daily at levels that could potentially result in withdrawal or rebound hypertension.