the goal with DAA

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  1. I've been on the bulk DAA for 3 days now. I smell nothing when I go.. I did the TCF-1 a while back & really liked it. Hoping to see the same results from the bulk.


  2. Something is wreaking havoc ( Oder wise) on me.
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  3. I sweat all day @ work, going through 3 shirts a day. I ALWAYS stink! Lol.

  4. Quote Originally Posted by DR.D View Post
    Magnesium Citrate for starters. That covers many, many bases.

    But yeah, I agree. People remember their livers, but generally neglect there kidneys. Juice markedly increases the retention of 3 elements: Nitrogen, Calcium and Phosphorus, and Calcium Phosphate is a common constituent of kidney stones. Not to mention, most people don't drink enough water. Magnesium and Potassium (especially the citrate forms) are good insurance to antagonize ureterolithiasis formation.
    Indeed. Pyridoxamine, one of the more bioactive Vitamin B6 forms, is another compound that exerts a powerful kidney protection function, in addition to its other benefits, including protecting against the deleterious cellular effects of the cross-linking of proteins and carbohydrates.

  5. Quote Originally Posted by strategicmove View Post
    Indeed. Pyridoxamine, one of the more bioactive Vitamin B6 forms, is another compound that exerts a powerful kidney protection function, in addition to its other benefits, including protecting against the deleterious cellular effects of the cross-linking of proteins and carbohydrates.
    Strategic, you have any recommendations for Pyridoxamine. Can't really find anything except for Life Extension. Also seen where true form has been banned by FDA for over the counter because pharma company is looking to use it for diabetic patients.
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  6. Quote Originally Posted by bludevil View Post
    Strategic, you have any recommendations for Pyridoxamine. Can't really find anything except for Life Extension. Also seen where true form has been banned by FDA for over the counter because pharma company is looking to use it for diabetic patients.
    What do you mean by "recommendations"?

  7. supplement wise. Any brands that you like

  8. Quote Originally Posted by bludevil View Post
    supplement wise. Any brands that you like
    Life Extension Foundation is the only one I trust, as far as this compound goes.

  9. Quote Originally Posted by strategicmove View Post
    Life Extension Foundation is the only one I trust, as far as this compound goes.
    Stacking this B6 vitamer with Carnosine could be a potent anti-AGEs strategy as well.

  10. Quote Originally Posted by DR.D View Post
    Stacking this B6 vitamer with Carnosine could be a potent anti-AGEs strategy as well.
    Absolutely. That is, in fact, the classic combo.

  11. whats the difference between Pyridoxamine and p5p ??

    i take NOW p5p does this have the same anti aging benifits?

  12. Quote Originally Posted by giantbrandon View Post
    whats the difference between Pyridoxamine and p5p ??

    i take NOW p5p does this have the same anti aging benifits?
    I think it probably does because P5P converts to the phosphated form of Pyridoxamine in some reactions, but to what degree I'm unsure. Perhaps strat can chime in.

  13. some good daa info in here...thanks guys!
    Iron Legion Rep

  14. Quote Originally Posted by giantbrandon View Post
    whats the difference between Pyridoxamine and p5p ??

    i take NOW p5p does this have the same anti aging benifits?
    The three vitamin B6 forms, pyridoxine, pyridoxal, and pyridoxamine, are all precursors to the coenzyme form, pyridoxal 5'-phosphate (P5P or PLP). Pyridoxamine is the form that has been shown to have the most important impact on AGEs-related anti-aging considerations. Nevertheless, P5P, like Dr. D suggested, should also exert related benefits.

  15. Quote Originally Posted by DR.D View Post
    I think it probably does because P5P converts to the phosphated form of Pyridoxamine in some reactions, but to what degree I'm unsure. Perhaps strat can chime in.
    Like pyridoxine and pyridoxal, pyridoxamine conversion to the coenzyme form, pyridoxal 5-phosphate (P5P or PLP), occurs via a sequential action of phosphotases, kinases, and oxidases. In particular, pyridoxamine is ultimately converted to PLP via intestinal phosphatase hydrolysis, and enzymatic actions of pyridoxal kinase and pyridoxine 5-phosphate oxidase.

  16. Quote Originally Posted by strategicmove View Post
    Like pyridoxine and pyridoxal, pyridoxamine conversion to the coenzyme form, pyridoxal 5-phosphate (P5P or PLP), occurs via a sequential action of phosphotases, kinases, and oxidases. In particular, pyridoxamine is ultimately converted to PLP via intestinal phosphatase hydrolysis, and enzymatic actions of pyridoxal kinase and pyridoxine 5-phosphate oxidase.
    You must spread some Reputation around before giving it to strategicmove again.

    lol

  17. Greetings.

    I plan on going on a Lean Xtreme, TestoPro, and bulk DAA run for 60 days. Lean Xtreme will only dosed at 2 caps/day, TestoPro 4/day, and DAA 3 g/day.

    Do you see a possible issue with the proposed stack?

    Thank you.

  18. Quote Originally Posted by abbazaba View Post
    Greetings.

    I plan on going on a Lean Xtreme, TestoPro, and bulk DAA run for 60 days. Lean Xtreme will only dosed at 2 caps/day, TestoPro 4/day, and DAA 3 g/day.

    Do you see a possible issue with the proposed stack?

    Thank you.
    Looks like a nice combo!

  19. Glad that you agree.

    I thought it has everything and couldn't pass it up - testofen, forskholii, 7-OH, divanyl, DAA.

    Only thing I am worried about is that it will be a 60 day cycle.

  20. Also, instead of an AI, I figured I'd try I3C - I am actually going to get some extra I3C on top of what is in TestoPro.

  21. Quote Originally Posted by abbazaba View Post
    Also, instead of an AI, I figured I'd try I3C - I am actually going to get some extra I3C on top of what is in TestoPro.
    Too much I3C can cause enzyme induction. If I was gonna choose, I'd maybe go with DIM instead, but I'm probably pretty alone in that opinion. Just don't get greedy with the doses and you'll likely be OK with a little additional I3C.

    Also, I wouldn't worry about 60 days. You can always cut it short if you get a bad vibe, but 60 sounds like a good plan with your stack.

  22. Quote Originally Posted by DR.D View Post
    I think it probably does because P5P converts to the phosphated form of Pyridoxamine in some reactions, but to what degree I'm unsure. Perhaps strat can chime in.
    Quote Originally Posted by strategicmove View Post
    Like pyridoxine and pyridoxal, pyridoxamine conversion to the coenzyme form, pyridoxal 5-phosphate (P5P or PLP), occurs via a sequential action of phosphotases, kinases, and oxidases. In particular, pyridoxamine is ultimately converted to PLP via intestinal phosphatase hydrolysis, and enzymatic actions of pyridoxal kinase and pyridoxine 5-phosphate oxidase.
    thanks guys, might get some and run it along side the p5p

  23. Quote Originally Posted by DR.D;
    Too much I3C can cause enzyme induction. If I was gonna choose, I'd maybe go with DIM instead, but I'm probably pretty alone in that opinion. Just don't get greedy with the doses and you'll likely be OK with a little additional I3C.....
    You are not alone, my friend! I have always argued for a preference of Indole-3-Carbinol (I3C) over Di-Indolyl-Methane (DIM). As is well known, apart from helping neutralize harmful estrogen metabolites by triggering so-called Phase I and Phase II detoxifying enzymes, indole-3-carbinol also favourably improves the ratio of "good" estrogens to "bad". In particular, it raises the levels of the beneficial 2-hydroxyestrone compared to that of the harmful 16-hydroxyestrone, in addition to supporting the stabilisation of DIM levels. On its part, DIM, the I3C metabolite, specifically addresses the potentially harmful estrogen metabolite called 4-hydroxyestrone. Both I3C and DIM may induce deceased-cell apoptosis and trigger DNA repair. Overall, several metabolites can be synthesized from I3C, including DIM. As a consequence, I3C has a broader set of beneficial biological actions than DIM. If I had to choose one of the two, it would be I3C. Nevertheless, the two can also make a nice stack.
    Product Educator | USPowders
    Statements made by this online persona are the sole property of the owner, and do not necessarily reflect USPowders’ opinion as a whole.

  24. Quote Originally Posted by strategicmove View Post
    You are not alone, my friend! I have always argued for a preference of Indole-3-Carbinol (I3C) over Di-Indolyl-Methane (DIM). As is well known, apart from helping neutralize harmful estrogen metabolites by triggering so-called Phase I and Phase II detoxifying enzymes, indole-3-carbinol also favourably improves the ratio of "good" estrogens to "bad". In particular, it raises the levels of the beneficial 2-hydroxyestrone compared to that of the harmful 16-hydroxyestrone, in addition to supporting the stabilisation of DIM levels. On its part, DIM, the I3C metabolite, specifically addresses the potentially harmful estrogen metabolite called 4-hydroxyestrone. Both I3C and DIM may induce deceased-cell apoptosis and trigger DNA repair. Overall, several metabolites can be synthesized from I3C, including DIM. As a consequence, I3C has a broader set of beneficial biological actions than DIM. If I had to choose one of the two, it would be I3C. Nevertheless, the two can also make a nice stack.
    The negative thing about I3C is the CYP1A2 induction, and to a lesser extent the CYP3A4 induction. Plus the increases in the serum concentrations of ALT (alanine aminotransferase) and enhanced development of cancer in animal models when given after carcinogen. I3C makes me nervous intentionally inducing these isozymes, especially with all the carcinogens constantly present in our environment and food-chain.

  25. Quote Originally Posted by DR.D View Post
    Combining Calcium with DAA can increase it's efficacy, but also it's side effects unfortunately. I don't like to take extra Calcium beyond what I get in my diet. It promotes kidney stones over time (especially in juicers) and reduces the absorption and benefits of magnesium (which I do supplement every night.)
    Would supplementing magnesium help circumvent that? It seems you prefer the normal DAA versus all the other stuff. I gotta be honest, I felt much better when I took the bulk stuff but it was also like a grenade in my colon...
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