cortisol problems do not occur ovrenight, but after weeks to months of over training, overworking, excessive stress, etc etc... thats why it is imperitave to take a diet supplement or product with high dosages on a "cycle" 4 weeks on 2 off.... when you have high amounts of caffeinie (dosage varies per person), your body uses the caffeine instead of the adrenaline, so your adrenal glands stop producing and cortisol is the result to manage the stress....
taking a caffeine products not gonna hurt, many cortisol products might be bs... more importantly... once awhile skip the stimulants and relax
Actually caffeine CAUSES adrenaline to be released, which also has an anti-catabolic effect as glucose is quickly released into the blood as a fight or flight mechanism.
The mode of action of caffeine on catecholamine release from perfused adrenal glands of cat.
Yamada Y, Nakazato Y, Ohga A.
Department of Pharmacology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
1
Adrenaline and noradrenaline secretion induced by caffeine was investigated in the perfused cat adrenal glands. 2 Caffeine (10-80 mM) caused a dose-dependent increase in both adrenaline and noradrenaline secretion when applied for 1 min and 10 min after replacing Ca2+ with 10(-5)M EGTA in the perfusion solution. The ratio of adrenaline to noradrenaline was about 1:1. Mg2+ and/or Ca2+ inhibited the response to caffeine. 3 When caffeine (40 mM) was repeatedly applied in the absence of extracellular Ca2+, the secretory response almost disappeared but only at the second challenge with caffeine. However, the response was partially restored after readmission of Ca2+ (2.2 mM) and was augmented after the readmission of Ca2+ with ouabain (10(-5) M). 4 Caffeine-induced secretion of adrenaline and noradrenaline increased with the increase in the preloaded concentration of Ca2+ and attained a maximum at 16 mM Ca2+. 5 During perfusion with Ca2+-free Locke solution containing hexamethonium (10(-3)M), acetylcholine (10(-4)M) caused increases in both adrenaline and noradrenaline secretions with a ratio of about 1:2. The secretory responses were partially inhibited by preceding stimulation with exposure to caffeine (80 mM). 6
These results suggest that caffeine mobilizes Ca2+ from an intracellular storage site that may not be entirely the same as that linked to muscarinic receptors, and causes an increase in both adrenaline and noradrenaline secretion from cat adrenal chromaffin cells.
. LX would probably be the way to go and it really is a helpful product while on any sort of cutting cycle since even caloric restriction can cause some problems in that department. Couple caloric restriction (below maintenance) with spiked cortisol levels and you have a recipe for muscle loss.
