if you are still eating grains, read this
- 04-29-2011, 08:56 PM
J Physiol Biochem. 2010 Jun;66(2):153-9. Epub 2010 Jun 1.
Gliadins induce TNFalpha production through cAMP-dependent protein kinase A activation in intestinal cells (Caco-2).
Laparra Llopis JM, Sanz Herranz Y.
Microbial Ecophysiology and Nutrition Group, Instituto de Agroquímica y Tecnología de Alimentos (CSIC), Apartado 73, 46100 Burjassot, Valencia, Spain. email@example.com
Celiac disease is an autoimmune enteropathy caused by a permanent intolerance to gliadins. In this study the effects of two gliadin-derived peptides (PA2, PQPQLPYPQPQLP and PA9, QLQPFPQPQLPY) on TNFalpha production by intestinal epithelial cells (Caco-2) and whether these effects were related to protein kinase A (PKA) and/or -C (PKC) activities have been evaluated. Caco-2 cell cultures were challenged with several sets of gliadin peptides solutions (0.25 mg/mL), with/without different activators of PKA or PKC, bradykinin (Brdkn) and pyrrolidine dithiocarbamate (PDTC). The gliadin-derived peptides assayed represent the two major immunodominant epitopes of the peptide 33-mer of alpha-gliadin (56-88) (LQLQPFPQPQLPYPQPQLPYPQPQLPYPQ PQPF). Both peptides induced the TNFalpha production triggering the inflammatory cell responses, the PA2 being more effective. The addition of the peptides in the presence of dibutyril cyclic AMP (cAMP), Brdkn or PDTC, inhibited the TNFalpha production. The PKC-activator phorbol 12-myristate 13-diacetate additionally increased the PA2- and PA9-induced TNFalpha production. These results link the gliadin-derived peptides induced TNFalpha production through cAMP-dependent PKA activation, where ion channels controlling calcium influx into cells could play a protective role, and requires NF-kappaB activation.
Regardless of your feelings, gluten is inherently inflammatory and should be avoided as much as possible.M.Ed. Ex Phys
- 04-29-2011, 08:58 PM
- 04-29-2011, 09:02 PM
Paleo is not ground breaking everyone should be eating fruits, veggies, good protein and eliminating processed food.
If you understand food, you find a food that fits you but we've been programmed to eat like robots starting in kindergarden...
My issue is the blind following and the cult like attitude towards food.
poor kids don't even know what a Cucumber looks like these days....
Everyone and mean everyone should understand the basic concept of food. the scary part is those that are teaching nutrition in gyms and such are quaks.
04-29-2011, 09:03 PM
04-29-2011, 09:04 PM
04-29-2011, 09:04 PM
04-29-2011, 09:05 PM
04-29-2011, 09:06 PM
04-29-2011, 09:07 PM
04-29-2011, 09:10 PM
04-29-2011, 09:14 PM
I've always had a problem with carbs. Every time I eat any type of carb I have to be near a bathroom. I follow the Metabolic Diet now and feel much better on low carb days. I still do the carb ups because I enjoy carbs but not the "side effects" they give me.
04-29-2011, 09:16 PM
04-29-2011, 09:27 PM
Posion and not the band...
In this same section someone posted a diet from a IFBB pro....gross.
Now the skinny kid in the classroom is laughed at...
04-29-2011, 09:29 PM
04-29-2011, 09:30 PM
Potatoes, yes, but corn, absolutely not. It is a highly GE and practically devoid of any source of nutrition or alkalinity.
M.Ed. Ex Phys
04-29-2011, 09:50 PM
I'm not sure how gluten containing prducts make me feel since I eat them every day.
But a few of my cousins have extreme gluten intolerance. If they even consume the slightest bit of gluten the start swelling and their airway becomes restricted and have to be rushed to the hospital.
04-29-2011, 09:55 PM
04-29-2011, 10:02 PM
Well now everything makes sense. You saw a female which you thought was fat who was the "head of some government for the education for obesity". I guess you think because the person may be slightly overweight in your eyes they can not teach or learn a certain subject. Yeah, that makes sense. So when you go to a restaurant, do check to make sure the cook is fat?. Because really if the cook isn't fat, he must not know enough about food to prepare your meal right?
04-29-2011, 10:24 PM
04-29-2011, 10:28 PM
04-30-2011, 12:44 AM
04-30-2011, 12:48 AM
04-30-2011, 12:52 AM
04-30-2011, 01:04 AM
04-30-2011, 01:22 AM
04-30-2011, 01:31 AM
Imo, more meat should/could be in his diet.
Eggs are great, I just dont recommend the majority of your meals consisting of them.
04-30-2011, 08:47 AM
I've actually noticed a lot of things while going on Paleo style/non grain, gluten, diary.
I'm not bloated anymore
I don't have crackling joints
I'm more vascular
I'm eating WAY more
I feel "cleaner", oddly seeing i'm eating like 180g fat, 260g protein..
I do a modified IF. I eat lunch, then a HUGE dinner. Imagine, 120g fat, and 200g protein.
I've lost weight
I also have a umbilical hernia. when I eat too much my intestines swell and it usually feels like it's coming out. Since eating full on fat/meat i've not had this problem.
I noticed when I ate curry, which has cornstarch and sugar in it I noticed sharp pain near my intestinal entrance. like side pain. About 1hr after eating it. And I felt flush.
After going home and eating about 200g of almonds I felt better.
Paleo is REALLY hard if you live in Japan and your future wife is Japanese, who believes in eating white rice as a meal...her breakfast is usually a donut (well I call it a donut, usually bread with chocolate filling, custard filing, or sugar coating.. or all...).
She's not "fat" but definitely skinny fat. She'll kill me if she read this.. haha.
But yea, all you ppl who are hating the paleo diet just give it a try for 30 days then see how you feel. You don't have to give up your carbs, just scale up your fats/protein. Or replace all your grains with yams/sweet potatoes, or fruits.
I'm no preacher, what you do is really up to you, but yea to me, if you eating the grains, sugars, whatever and feeling and looking great, then just keep doing it.
04-30-2011, 09:03 AM
04-30-2011, 09:11 AM
You (as in the majority of AM, not you rodja personally) may not know this, but Dr. Keys suggestions about limiting fats and cholesterol were actually turned down by the FDA 5 years in a row. The FDA only adopted them when Keys himself joined the board.
Now, onto the topic of eggs.
The SOURCE is just as important as the food. Eggs bought in the supermarket are much different from eggs bought from a local cage free farmer.
Supermarket eggs can be left standing up to 60 days.
Mass produced eggs are from chickens fed a CORN diet. And we all know how harmful corn oil is.
Even your typical "free range/cage free" eggs are not cage free. All it takes to be called "cage free" is a 6" door opening in the cage and a small (about 3 square foot - if memory serves me) area of pen space per 100 chickens.
That's hardly cage free.
My family raised chickens when I was a child for the eggs. We had about 6 and they roamed the yard freely. There is a HUGE difference between the taste and consistency of those eggs vs. the ones in the store labeled "cage free".
Locally grown cage free eggs - eat all you want.
Mass produced and supermarket cage free eggs - be wary.
04-30-2011, 09:49 AM
04-30-2011, 09:59 AM
This thread has actually gotten me wondering about something. This is just me thinking out loud. But it's entirely possible when so many people complain about being "carb sensitive" and that they can't lose weight unless they really really restrict their carb intake. IMO it's entirely possible (not in ALL cases) that really it has nothing to do with them being "carb sensitive" it's the fact that they are sensitive to gluten not carbs. Because in my observation 99 percent of the time when guys add clean carbs into their diet, it's something with gluten in it like oatmeal.
I would be willing to bet if they kept their carb intake the same, but changed those carbs from something non wheat/gluten that they would be very surprised how many carbs they eat and still maintain their leanness.
04-30-2011, 10:19 AM
04-30-2011, 10:24 AM
I would say thos are the people who are gluten intolerant... to an extent but not fully celiac.
when i eat carbs i always keep them gluten free, and high fiber. no stomach issues here.
04-30-2011, 10:29 AM
04-30-2011, 10:31 AM
04-30-2011, 11:47 AM
04-30-2011, 12:11 PM
04-30-2011, 12:26 PM
That said, using vague terms like inflammatory and poison without data to back it up is in my opinion wrong. Lifting weights is inflammatory. Am I going to stop? Not likely. Gluten allergy is a very real and serious issue, but, again in my opinion, has been taken too far. Many foods that contain gluten have been the staple food of civilizations for centuries. It just seems to me to be an article that belongs more on a website that promotes veganism and cleanses. All of that is just my two cents though and as always, if it works for you, then it works for you and I'm not going to tell somebody not to do something.
04-30-2011, 12:33 PM
M.Ed. Ex Phys
04-30-2011, 12:36 PM
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