Jan's BloodTest April13/2007

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  1. My little Adrenals study posted here:

    http://forum.mesomorphosis.com/554378-post13.html

    ===========================
    Summary,
    when testing Adrenals ask for following Quest tests

    Sodium
    Potassium
    Cortisol not sure yet which one, so many tests but noted that AM/PM is not available from Nichols Institute, probably of low value.
    The VA location have 2,3,4,5,6 specimens, possibly those.
    http://cas2.questdiagnostics.com/scr...&tmradio=title

    http://cas2.questdiagnostics.com/scr...SearchString2=

    Aldosterone, LC/MS/MS, Serum http://cas2.questdiagnostics.com/scr...&tmradio=title
    Aldosterone, 24-Hour Urine (19552X) - (7062N) http://cas2.questdiagnostics.com/scr...&tmradio=title
    Aldosterone (LC/MS/MS)/Plasma Renin Activity Ratio - (11183Z) http://cas2.questdiagnostics.com/scr...&tmradio=title
    Plasma Renin Activity (10537X) Code: 10537N http://cas2.questdiagnostics.com/scr...&tmradio=title
    ============================== ============================== ============================== ====================
    http://www.endocrine.niddk.nih.gov/p...on/addison.htm
    Addison's disease
    Causes
    Symptoms
    Diagnosis
    Other Tests
    Treatment
    Special Problems
    Patient Education
    For More Information
    =========================
    ========
    http://www.endocrine.niddk.nih.gov/info/index.htm

    Information About Endocrine and Metabolic Diseases
    Acromegaly
    Addison’s Disease
    Cushing’s Syndrome
    Cystic Fibrosis (from NHLBI)
    Endocrine and Metabolic Diseases Organizations
    Graves’ Disease
    Human Growth Hormone and Creutzfeldt-Jakob Disease
    Hyperparathyroidism
    Hyperthyroidism
    Hypothyroidism
    Multiple Endocrine Neoplasia Type 1
    National Hormone and Pituitary Program: Information for People Treated with Human Growth Hormone (Comprehensive Report)
    National Hormone and Pituitary Program: Information for People Treated with Human Growth Hormone (Summary)
    Organizations, Directory of
    Pregnancy and Thyroid Disease
    Prolactinoma
    Turner Syndrome (from NHGRI)


  2. Copied from:
    What is considered high levels of prolactin?

    Quote Originally Posted by JanSz View Post
    Prolactin secretion is stimulated by sleep, stress (physical and emotional), and the hypothalmic hormone (TRH). Prolactin secretion is decreased by dopamine analogs such as bromocriptine.
    Hypersecretion of prolactin can be caused by pituitary tumors, hypothalmic disease, breast or chest wall stimulation, hypothyroidism, renal failure, acute excercise, stress, eating, and several medications(eg; pheno-thiazines, metoclopramide). Hyper-prolactinemia inhibits gonadothropin secretion and can produce hypogonadism in men and women with accompanying low or inapropriedly "low normal" LH and FSH levels.

    Quest Diagnostics
    EndoManual_3rdEd_2004 page 311

    Prolactin have no known role in male. page 205


    Quote Originally Posted by Dr. John View Post
    Eating, or having sex, can bring PRL to 30. Did you eat within two hours of the draw? How does midrange PRL look now?

    PRL of 300 (!) is pathognomic of a pituitary tumor.

    I hope this FINALLY gives you guys some perspective. Some of this stuff gets just plain silly: manipulating hormones for no reason whatsoever, when they are well within healthy level. Any time you alter a hormone, you are asking for trouble. THAT is how Interventional Endocrinology should be viewed.
    My take home message:
    as long as Prolactin is within range it should be ignored and not manipulated.

    If it is within range then: Prolactin have no known role in male. and that includes effects on sex.

    This message is copied to my diary as my current view on Prolactin.

    Thank you Dr John for your persistence thru many posts when holding your view on Prolactin.
    •   
       


  3. What I have learned about TRT (under construction)

    When on TRT your goal is to keep your FreeT in upper range but not over it.
    FreeT tests are unreliable, possibly except at Quest Diagnostics and only the one that is on my list of blood tests, post #44
    If you have that test available, look also at BAT level, keep it in upper range.

    Other choice (supposedly used by Dr Shippen) is to use a chart, post #41
    On that chart desirable range is (160-250), 100 being really the lowest with any hope.

    FreeT level depends on
    Total Testosterone
    and
    SHBG
    and Albumin to some extent, we are not going to worry too much about Albumin.

    Total Testosterone depends on
    testicles production
    and
    Testosterone injections ( I consider transdermals as rather overly variable specially since many people have some or heavy thyroid problems)

    Testicles may be able to produce T (Secondary) or not (Primary)
    Testicles that are able to produce but do not have enough signal (LH, FSH) are induced to production by using HCG.
    Use of HCG while on T is always recomended because it keeps testicles full (otherwise they will shrink).
    Sometimes HCG may be used as sole TRT, but it rarely works.
    Ideal dose of HCG is 100-250iu daily, not practical.
    Someone who likes to keep their sperm fertile should probably use E2D, every two days schedule, 250iu-dose.
    If fertility is or is not at issue E3D schedule is also acceptable, every three days, 500iu-dose.
    Someone who is not able to get HCG should not worry too much, yes his testicles will shrink and stop any production.
    Testicles can be brought back to size latter on when HCG became available, not sure about fertility.
    When fertility is at issue (in the worst way), use daily (hcg-100iu and HMG-75iu) for three months to a year while trying to conceive.

    When there is a need for testosterone injections use cypionate or enanthate.
    Assuming that testcles are absent or adding (some) correction when indigenous production is known, preliminary dose of testosterone can be

    calculated
    when SHBG and last Total T is known.
    Use chart post #41, and table post #40
    table gives weekly dose (XXX mg/week)
    that dose have to be converted to volume, cc or/and units (on insuline syringe)
    Density of testosterone need to be known. Most often 200mg/mL is used but also 100mg/mL is available.
    Weekly volume need to be converted to a volume for each shot for E2D or E3D routine of injections.
    I do not consider weekly or less often injections, specially for those with low SHBG since the TT variability is a frequent source of emotional stress.
    Example,
    calculate size of individual shot
    weekly dose 130mg
    200mg/mL testosterone density
    E3D routine
    (130mg)/(200mg/mL)=0.65mL/week
    0.65mL/week=0.65cc/week=65 units/week
    65/7*3=27.9~28 units each shot

    E2D or E3D routines that is a lots of shots, specially when considering large needles that are customarily used.
    Also with large needles injections are very quick causing additional tissue damage and pain lasting sometime days.
    For this and other reasons I prefer SubQ shots around navel using smallest available needle.
    It takes 4 minutes to get the testosterone into syringe and then a minute to inject it in.
    I consider that time well spend, any sorenes last no more than 10 minutes after the shot.
    I curently use 5/16" long needle, but am considering change to 1/2" long since tiny bit of oil escapes after about every other shot.
    Not sure if it is worth the effort since going to 1/2"long needle would mean also going to thicker (39ga) needle.
    There are at least two suitable types of syringes available for purchase:
    http://hocks.com/Merchant2/merchant....Category_Code=
    BD Ultrafine II U-100 Insulin Syringe 31 Gauge 3/10cc 5/16inch Short Needle--1/2 Unit Markings 100/b Price: $25.95
    and
    http://hocks.com/Merchant2/merchant....Category_Code=
    BD Pen Needle Short 31 Gauge 3/16inch 100/box

    Bottom line, E3D routine
    both T&hcg shots on same day, then two days free of shots
    --------------------------------------------------------------------------------------------------
    While on TRT estrogens have to be monitored, all estrogens, as in blood test list post #44
    I use LEF life Extension Foundation products
    DualAction 5 pills ( for cruciferous, I3C & DIM content)
    TMG 2 pills

    I also use Arimidex or actually the liquid version for ease of use.
    I use insuline syringe with cut off needle to get my dose.
    I use Arimidex on E3D schedule, same as my T&hcg for simplicity.
    I use 0.5cc=50units=1/2pill eact time, dosing must be verified by testing.

    ------------------------------------------------------------------------------------------------
    I do blood tests once/year per my list, post #44
    also 2-4 tests thruout the year on as need basis.
    Full test is fully paid by my insurance (Medicare) when supported bt ICD-9 codes (provided in post #41)

  4. Quote Originally Posted by JanSz View Post
    I consider transdermals as rather overly variable specially since many people have some or heavy thyroid problems)
    But many professionals in the field consider them a first-line option, and many man who use them are entirely satisfied with the result. Our own Dr. Crisler believes that TD's are preferable to injections because they mimic normal physiology more closely than injections.


    Quote Originally Posted by JanSz View Post
    Sometimes HCG may be used as sole TRT, but it rarely works.
    hCG can produce a good result in properly selected individuals. It is best-suited to men in early middle age having relatively modest secondary hypogonadism.

  5. Dr Marianco on low SHBG
    Attached Files Attached Files
    •   
       


  6. --------------http://anabolicminds.com/forum/962870-post13.html

    estrone to e2 convresion

    Quote Originally Posted by RPHMark View Post
    I forget people outside pharmacy don't always know RPh is the designation for registered pharmacist. I do quite a bit of compounding bio-identical HRT (mostly for women). Obviously, I don't know their case details, but many women present with anxiety/panic attack type symptoms (who have previously never had them) duing the peri-menopausal timeframe. Normally this is due to a drop in progesterone/estrogen dominance and normally associated neurotransmitter levels falling. As you probably know heart racing, breathing problemss, and chest pain are common with this, so maybe that could be what is going on. This would not likely show up on any of the typical ER labs either. Many drs won't test actual hormone levels. We all know this should be standard practice, but it is not. Many will test LH/FSH and say they are "fine", but those levels don't generally change much duing peri-menopause as progesterone is the primary problem. To find a good HRT dr. work backwards. Go to a compounding pharmacy with a good reputation and ask them what dr to see. You can go through a group called IACP (International Acadamy of compounding pharmacists) to find a compounding pharmacy.
    Compounding Pharmacist Locator
    International Academy of Compounding Pharmacists:

    International Academy of Compounding Pharmacists: Home

    If you are unable to locate a compounding pharmacist within a 100 miles radius, please contact our toll-free referral line at 800-927-4227.
    ============================== =================
    The Medicine Shoppe
    146 Us Highway 206
    Andover, NJ 07821-4518
    (973) 786-5300
    Henry Gialanella
    146 Main St

    20 miles from ZIP 07054
    Company Name The Alchemist Shoppe
    Pharmacist Linda Witzal R.Ph.
    Address 3175 Route 10 E.
    Denville NJ 07834
    Phone (973) 328-4477
    URL scream and cream alchemist chris at alchemistshoppe.com
    Distance Approx. 5 Miles

    Company Name Pharmacy Creations

    Pharmacist Scott Karolchyk "R.Ph., FIACP"
    Address 540 Route 10 West
    Randolph NJ 07869
    Phone (973) 328-8756
    URL Pharmacy Creations News Items
    Distance Approx. 8 Miles



    Company Name Pompton Pharmacy

    Pharmacist David Stahlberger "R.Ph., FIACP"
    Address 558 Newark Pompton Turnpike
    Pompton Plains NJ 07444
    Phone (973) 839-4200
    Distance Approx. 9 Miles



    Company Name Sheefa Pharmacy & Wellness Center
    Pharmacist Ashraf Latif R.Ph.
    Address 405 Central Avenue
    East Orange NJ 07018
    Phone (973) 673-6800
    URL Welcome To Sheefa Pharmacy
    Distance Approx. 11 Miles



    Company Name Clifton Pharmacy & Compounding
    Pharmacist Howard Bleznick R.Ph.
    Address 595 Van Houten Avenue
    Clifton NJ 07013
    Phone (973) 777-2428
    Distance Approx. 12 Miles


    Company Name Medicine Shoppe
    Pharmacist Jillian Hocking Pharm. D.
    Address 36-A Main Street
    Bloomingdale NJ 07403
    Phone (973) 838-0909
    Distance Approx. 12 Miles


    Company Name Medicine Shoppe
    Pharmacist Daniel Albizati R.Ph.
    Address 559 Franklin Avenue
    Nutley NJ 07110
    Phone (973) 235-0909
    Distance Approx. 13 Miles



    Company Name Belvidere Pharmacy
    Pharmacist George Grumet R.Ph.
    Address 349 Somerset Street
    North Plainfield NJ 07060
    Phone (800) 322-1302
    Distance Approx. 15 Miles



    Company Name Millers of Wyckoff
    Pharmacist David Miller R.Ph.
    Address 678 Wyckoff Avenue
    Wyckoff NJ 07481
    Phone (201) 891-3333
    URL Millers Pharmacy
    Distance Approx. 15 Miles



    Company Name Belvidere Pharmacy

    Pharmacist Shara Rudner "R.Ph., FIACP"
    Address 349 Somerset Street
    North Plainfield NJ 07060
    Phone (908) 756-6695
    Distance Approx. 15 Miles



    Company Name Rock Ridge Pharmacy

    Pharmacist Matthew Kopacki "R.Ph., FIACP"
    Address 191 Rock Road
    Glen Rock NJ 07452
    Phone (201) 444-4190
    Distance Approx. 16 Miles


    Company Name Town & Country Pharmacy

    Pharmacist John Herr "R.Ph., FIACP"
    Address 60 E. Ridgewood Ave.
    Ridgewood NJ 07450
    Phone (201) 447-2020
    Distance Approx. 17 Miles

    ============================== ============================== =======================

    Company Name Dorneyville Pharmacy

    Pharmacist Tom Silvonek "R.Ph., FIACP"
    Address 3330 Hamilton Blvd.
    Allentown PA 18103
    Phone (800) 850-2196
    Distance Approx. 2 Miles



    Company Name "Hartzell's Pharmacy, Inc. Home Heal"
    Pharmacist Robert Hartzell R.Ph.
    Address 300 American Street
    Catasauqua PA 18032
    Phone (610) 264-5471
    Distance Approx. 3 Miles



    Company Name DelPrete's Pharmacy
    Pharmacist Keith Delprete R.Ph.
    Address 3437 Rt. 309
    Orefield PA 18069
    Phone (610) 395-2602
    Distance Approx. 7 Miles



    Company Name Medicine Shoppe
    Pharmacist Phillip Bennett R.Ph.
    Address 1408-2 W. Broad Street
    Quakertown PA 18951
    Phone (215) 536-5595
    Distance Approx. 12 Miles



    Company Name Professional Pharmacy
    Pharmacist David Stone Pharm.D.
    Address 931 Main Street
    Pennsburg PA 18073
    Phone (215) 679-9700
    Distance Approx. 14 Miles

    ============================== ============================== ===============

    also

    American Osteopathic Association

    and

    American Osteopathic Association

    Find an Osteopath : General Osteopathic Council

    healthfinder.gov - Osteopath

    Stop The Thyroid Madness » ADRENALS FAQ–the most frequently asked questions

    Stop The Thyroid Madness » How to find a GOOD DOC

    Thyroid Disease Information Source -- Bestselling Books, News, Information on Living Well With Hypothyroidism, Autoimmune Disease, Thyroid Diet, Home Page of Mary Shomon

    Physician that use ArmourThyroid
    ============================== ============================== =====================
    Quote Originally Posted by RPHMark View Post
    You have some great pharmacists in your area. Scott Karolchyk, Matt Kopacki, and John Herr are ones I have spoken with at conferences before and all of them really know their stuff. Any of the ones with FIACP after their names are fellows in IACP which is an accomplishment.
    ============================== ==
    ============================== ============================== =======================
    The World Health Network - Anti-Aging and Longevity
    look under directory
    ============================== ============================== =================
    ============================== ===
    ---------------------------------------------
    Aleksandr Martirosov, DO
    31-00 Broadway
    Fair Lawn, New Jersey 07410
    (210) 475-5006
    [email protected]
    ---------
    Family Medicine
    Addiction Medicine
    Anti-Aging Medicine
    Ostheophatic Medicine
    ---------------------------------------------
    Forward J Brent MD
    195 US Hwy 46
    Mine Hill, NJ 07803-3163
    (973)366-8884
    ------------------------
    Patrick Barrett DO
    (631)472-6000
    4568 Sunrise Hwy Oakdale, NY 11769-1012
    in case I need new doc, good one to ask for reference,
    (84.8 mi – about 1 hour 42 mins (up to 2 hours 20 mins in traffic)
    he works with a lot of bodybuilders, hes a DO and hes a GP

    ------------------------
    Anti-Aging Medicine

    Jeffrey Dach MD Bio-Identical Hormone Blog

    Find a Doctor
    Anti-Aging Physicians, Clinics & Products - WorldHealth.net
    =====================
    very nice search engine:

    Integrative Medicine Physicians - American College for Advancement in Medicine
    ============================== ============

    Doctor Referral List

    http://ucprx.com/doctor_referral_list


    ........
    http://www.osteopathic.org/osteopath...s/default.aspx

    http://www.osteopathic.org/osteopath...s/default.aspx

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    EDUCATIONAL THREADS
    ----------http://forums.steroid.com/forumdisplay.php?f=12]EDUCATIONAL THREADS - Anabolic Steroids - Steroid.com / Anabolic Review Forums

  8. http://anabolicminds.com/forum/male-...tml#post991716

    ============================== ============================== ============
    I am posting this response here and on the thread where dr Delgado made his statement.
    Hopefully we will get some words from him.


    http://anabolicminds.com/forum/991716-post165.html
    http://anabolicminds.com/forum/991863-post166.html
    Quote Originally Posted by DrDelgado View Post
    I will also suggest that aging is going to include a decline of hormones,
    within genetic differences, expect to augment back Testosterone,
    I keep mime and my clients under doctors monitoring,
    around 1000 to 1,200 ng/ml Total T,
    and Free T at upper range of 200 to 300 (or 20 to 40 pg/mldepending on the nomenclature)
    Aldosterone is best at 10 to 40 ug/24 hr,
    IGF-1 around 250 to 400 ng/ml.
    DHT 60 to 70 ng/dl,
    DHEA 300 ug/dl,
    insulin under 5,
    SHBG 10 to 30 nmol/l,
    Estradiol 35 pg/ml,
    with about 20 (2OHE) to 1 -16aOHE.

  9. JansZ
    I noted that you take high dose Chrysin now via lef products.

    You jumped from 1 - 2 pills to 7 pills right in between BW?

    Take note that Chrysin might not be an effective form of T boosting or E control

    I have had discussions with Eric over at PP about this.

    They removed Chrysin and reworked Dermacrine Sustain - "Basically, we removed chrisin to make room for more resveratrol and 7,8 benzoflavone. Plus there is some research showing that high-doses of chrysin can inhibit the enzyme which converts Adione to Test (17HSD) so we removed it to make room for the more effective T boosters."

    There is also another thread floating around here that has a MD backed study showing Resveratrol to be much more superior than chrysin for controlling E.

    I would dump the product your taking and just go for straight RSV. Check out this thread, pages 3 in specific Resveratrol really cheap

    I noted that you cannot go transdermal form, so look for revgentics which sells massive doses of RSV, specifically the X500. 500mg pure RSV. Cut pill in half

  10. Quote Originally Posted by plymouth city View Post
    JansZ
    I noted that you take high dose Chrysin now via lef products.

    You jumped from 1 - 2 pills to 7 pills right in between BW?

    Take note that Chrysin might not be an effective form of T boosting or E control

    I have had discussions with Eric over at PP about this.

    They removed Chrysin and reworked Dermacrine Sustain - "Basically, we removed chrisin to make room for more resveratrol and 7,8 benzoflavone. Plus there is some research showing that high-doses of chrysin can inhibit the enzyme which converts Adione to Test (17HSD) so we removed it to make room for the more effective T boosters."

    There is also another thread floating around here that has a MD backed study showing Resveratrol to be much more superior than chrysin for controlling E.

    I would dump the product your taking and just go for straight RSV. Check out this thread, pages 3 in specific Resveratrol really cheap

    I noted that you cannot go transdermal form, so look for revgentics which sells massive doses of RSV, specifically the X500. 500mg pure RSV. Cut pill in half
    Thanks for your concern.
    I stopped using Chrysin over two moths ago.
    Looking at my April's test, I came to conclussion that I should reduce pressure on my SHBG.
    Specially that I am aiming at TotalT~(1100-1200) and FreeT~300 per Nick Delgado rather than previous FreeT~250 per dr Shippen.
    There is two SHBG positions on that test, 20 and 24.
    I was getting Chrysin from LEF's
    Super MiraForte with Maximum Strength Chrysin
    Super Miraforte With Max Strength Chrysin, 120 Caps
    that product contains Nettle (Urtica dioica) which lowers SHBG.

    I also take 200mg resveratrol, separately, this is on top of resveratrol that I am getting with DualAction.

    When I changed from Tcream to Deopo-Testosterone shots on june 19/2007 I added Liquidex 0.5cc with each shot, I use E3D schedule.
    =====================
    I had doctor visit tonight.
    I will be doing Metabolic Analysis Profile.
    Genova Diagnostics

    I have seen (partial) results from my last blood test.
    Pregnenolone is on the bottom of range
    I am increasing from 1gram to 2 grams preg cream

    DHEAs is below range, I will start using DHEA again, probably 100mg

    Do not know what to think (could use help) about my (blood serum) Aldosterone=1.0ng/dL(<or=28)
    In April it was=4
    Quest Diagnostics: Test Menu

    I thought that Aldosterone should be in high teens or even 20's

    Should I reduce salt, increase Potassium, what to do???
    Lately I use more salt then I used to use in my life (taste good, not sure if I need the salt).
    ----
    Note on Quest web site.
    Because
    serum aldosterone concentrations vary due to dietary sodium
    intake and body position, some physicians prefer
    measurement of 24-hour urine concentrations for
    aldosterone.

  11. I wouldn't sweat the aldosterone reading.

    Unless I see low aldo confirmed by urinary analysis I don't buy much into it.

    Your DHEA and Preg both went down.

    Want to bet that your TT is sky high right now, way above the 4 something range it was before?

    This is common for other androgenic hormones to crash when exogenous T is administered. By knowing that, Im betting 10 -1 your shots are working.

    Im not a fan of oral DHEA.

    Get some Dermacrine JansZ. I think they have a superior delivery system than the usual preg compounded cream you get from a script, plus the added bonus of DHEA transdermal. Start at half dose. Plus added resveratrol and benzoflavone 7,8 in it.

    Where do you get resveratrol( you netioned 200mg a day) LEF is way to expensive. Check my "resveratrol really cheap" post, I like revegentics for pure RSV, the X500, VERY cheap.

  12. Ok, so I have my blood test result from 8/30/07 blood draw.
    They shorted me on
    Testosterone, Free, Bio/Total (LC/MS/MS)
    Dihydrotestosterone, Free, Serum (36168X)
    so next script is on a way and I will have to get poked again.

    There is two Estrodial results, from description I thought that both were ultrasensitive, but I got different results.
    I am going with the one that comes with FreeE2
    My freeE2 is high, (but my pines is working ok).
    I am incresing Liquidex from 0.5 to 0.6cc E3D
    so my weekly dose is now
    0.6*7/3=1.4cc/week
    increase from
    0.5*7/3=1.17cc/week

    my Fibrinogen=424(175-425)
    LEF wants (180-250)
    I asked doc for TRENTAL®
    (pentoxifylline)
    Tablets, 400 mg
    1 or 2 tablets daily
    will see what comes out of this request

    FreeT3 freeT4
    9/16/07 I upped Armour from 3grains to 3.5
    also asked for script for Synthroid 25mcg, I will use 1pill/day.

    9/20/07 Changed back to 3grains plus 2pills Synthroid 25mcg.
    Hopefuly my body can convert some T4-->T3 and I raise both FreeT4 and FreeT3
    will be watching pulse and temps.
    ---------
    Pregnenolone/DHEA

    I upped preg cream from one to 2grams/day
    Started on DHEA, 100mg/day

    ----------------------------
    Genova Diagnostics
    EstroEssence
    and

    Metabolic Analysis Profile and Cellular Energy Profile
    out for testing
    Monday Oct1/2007

    ============================== ============================== ============
    Oct1/2007
    finaly received testosterone results (after second poking), they still omitted DHT.
    .
    68 Testosterone, Free, Bio/Total (LC/MS/MS) Quest Diagnostics: Test Menu
    69 /------------------------------------ 1151 (250-1100) ng/dL Testosterone Total
    70 /------------------------------------ 248.5 (46-224) pg/mL Testosterone Free
    71 /------------------------------------ 456.9 (110-575) ng/dL Testosterone Bioavailable
    72 /------------------------------------ 26 (17-54) nmol/L SHBG
    73 /------------------------------------ 4.0 (3.6-5.1) g/dL Albumin, serum
    74 Dihydrotestosterone, Free, Serum (36168X) --------- Quest Diagnostics: Test Menu
    75 /------------------------------------ 69 (25-75 ) ng/dL Dihydrotestosterone
    76 /------------------------------------ 7.52 (1.00-6.20) pg/mL Dihydrotestosterone, FREE
    77 /------------------------------------ 1.09% (0.62-1.10) % Dihydrotestosterone, FREE %




    ------
    My goal
    FreeT~300, =(248.5-46)/(300-46)=0.7972 (dose is short 20%)
    BAT~575 (top range), =(456.9-110)/(575-110)=0.7460 (dose is short 25%)

    730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910
    449 454 459 463 468 473 477 482 487 491 496 501 505 510 515 519 524 529 533

    920 930 940 950 960 970 980 990 1000 101 102 103 104 105 106 107 108 109 110
    538 542 547 552 556 561 566 570 575.0 580 584 589 594 598 603 608 612 617 622



    I am still short on both
    The test represents my Depo-Tshots=30units at E3D schedule.
    My new dose should be around
    =30/0.75=40units=186.7mg/week
    =30/0.8=37.5units=175mg/week
    conservatively I make my new dose =38units=177.3mg/week
    ------
    Note1, using dr Shippen chart my FreeT=325pg/mL
    Note2, using (totally unreliable BAT)(but FreeT sort of close)
    Free & Bioavailable Testosterone calculator

    FreeT=343 pg/mL
    BAT=750ng/dL
    .
    Note3, the 31GA 5/16"long leaked out little bit of oil, changed (over month ago) to 30Ga 1/2"Long
    .
    .
    .............................. .............................. .................


    they have Novarel.
    No Novarel
    -----------------------------------------------------------------------
    Note, nov9/07
    For a while I have changed Novarel from 500iu on the day of T shots to 250iu on both days between T shot.
    My testicles are little firmer, scrotum hangs low more often.
    Since now I am doing shots every day, I decided to do T shots E2D and 250iu in beween.
    Testosterone was 38units now 38/3*2=25.33~ 25.5units
    38*7/3=


    my weekly dose is:
    =0.255*200*7/2=178.5mg/week

    my old weekly dose, the one corresponding to current test results was 0.3*7/3*200=140
    I expect that my BAT should raise to 456.9*178.5/140=583
    actually even more because blood was drawn on third day, but now it will be drawn on second day after T shot.

    Liquidex on days of T shot, 0.6/3*2=0.4cc
    Dec6/07
    Started Anastrozole from ChemOne Research it is sweet and do not sting, wonder if will work.
    Dark in color, hard to see numbers on syringe.
    Some morning wood problems, decreasing dose to 0.36=36units
    0.36*7/2=1.295cc/week Arimidex pills/week
    Dec20/07
    EstroEssence from Dec13/07 shows low urine E2
    Change Anastrozole to 0.33*7/2=1.155cc/week

    Feb29/08
    Stopped DualAction, BreastFormula, MiraForte
    Started 2 scoops DIM-Powder
    Change Anastrozole to =0.38*7/2=1.33cc/week
    Piston on my 3/10cc syringe is 6 units high, top of piston is at 38+6=44
    Mar15/08 Anastrozole 45units (45+6=51) .45*7/2=1.575

    --------------------------------------------------------------------------------)



    My E2 story


    See erection weakness.
    Blood drawn 3/19/08, reported 3/31/2008
    DHT=81(25-75)
    E2=4(< or =29)
    E2, Free=.07(< or = 0.45)
    E2,%Free=1.82(1.25 - 1.85)

    Stopped Anastrozole, 3/31/08
    ---
    Pines worked best while in Atlantic City (May 25/08)
    ---
    See erection weakness
    Blood drawn 5/23/08, reported 6/4/08 (instead of 48 hrs, had to draw 24 hrs after T shot, so the TT values are little higher)

    E2D schedule, T=25.5units=178.5mg/week, HCG=500iu
    No Anastrozole since 3/31/08

    TT=1117(250-1100)
    BAT=584.6(46-575)
    FreeT=303.5(46-224)
    SHBG=18
    Albumin=4.2
    DHT=77(25-75)
    E2=39(< or =29)
    E2, Free=1.07(< or = 0.45)
    E2,%Free=2.73(1.25 - 1.85)
    Note:
    See erection weakness, but week ago was still strong.
    Most likely I feel best at E2=29
    June 10/08, restarted Anastrozole
    0.25cc/E2D=0.25*7/2=0.875/week
    about June 15 changed to 0.25cc every day

    June 26/08 first night with strong nightly wood.
    (today is my HCG day, no Anastrozole until second T shot)
    =================

    8/02/08
    Estradiol, Ultrasensitive, LMMSMS=15(<29pg/mL)
    I was using Anastrozole(liquid) before this test, now stopped completely.
    ===============

    1/6/2009
    For no particular reason I decided to change from 25units to 0.22cc=22units each T-shot.
    Mostly because my last SHBG was going down, also I am on 2 ejaculations a week, down from three.

    I plan next blood test end of Feb may be March depending how I feel.
    If I extend to April then will do long test.

    Experiments with glucose/insuline, vegetable juicing, heavy duty probiotics, enzymes, pre-biotics, chlorella,
    result with 1.5 weeks of liquid stool.
    Suspect mostly because of chlorella and change in vitC.
    Previously vitC from NowFoods now changed to LEF brand.
    LEF brand may be the real thing, 3grams/day, 2 morning, 1 evening.
    My list od supplements is now much shorter, very basic, this is in preparation for SpectraCell5000 test.
    Experiments with NutrEval indicate tremendous variations between tests.
    Hopefully will have better luck with following SpectraCell5000.

    (Loose/liquid stool) If not the above, then may be it is a comeback of lactose intolerance, as it was 2005/2006.




    ----------------------------------------------------------------------------------------------------



    Discussion with colkurtz_spf about hcg level.
    HCG not restoring ball size.
    .
    I am going back to 31ga 5/16"long needle 3/10cc
    the dose will fit in that small volume syringe
    Any leaking is small any how, 30ga 1/2"long needle also leaked sometime
    minimizing scar tissue is more important to me.
    .
    -----------------------------------------------------------------
    Located study:
    Low-Dose Human Chorionic Gonadotropin Maintains
    Intratesticular Testosterone in Normal Men with
    Testosterone-Induced Gonadotropin Suppression
    http://calendar.hsl.washington.edu/d...Dose_Human.pdf

    Study shown that:
    125, 250, or 500 IU hCG every other day

    Posttreatment
    ITT was 25% less than baseline in the 125 IU hCG group,
    7% less than baseline in the 250 IU hCG group, and
    26% greater than baseline in the 500 IU hCG group.
    ---------------------------
    I am changing my HCG dose to 110%
    my new dose of HCG=380IU=19units I dissolve hcg in 5mL Bwater.
    today 11/30/2007
    ============================== =================
    Pregnyl® 1500IU - X-PIL
    Pregnyl® 1500 I.U.
    Pregnyl comes as 2 ml ampoules of dry white powder with 1 ml ampoule of solvent.
    ============================== =================
    Pregnyl® 5000IU - X-PIL
    Pregnyl® 5000 I.U.
    Pregnyl comes as 2 ml ampoules of dry white powder with 1 ml ampoule of solvent. That is very little amount of solvent, reason not to buy it.
    ============================== =================
    Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression -- Coviello et al. 90 (5): 2595 -- Journal of Clinical Endocrinology & Metabolism
    Low-Dose Human Chorionic Gonadotropin Maintains
    Intratesticular Testosterone in Normal Men with
    Testosterone-Induced Gonadotropin Suppression
    © 2005

    ============================== =========================

    ADDED 10/12/2010

    http://mus clechatroom.com/forum/showpost.php?p=115322&postcoun t=85
    Serum 17-hydroxyprogesterone strongly correlates w... [Fertil Steril. 2008] - PubMed result
    Fertil Steril. 2008 Feb;89(2):380-6. Epub 2007 Apr 26.
    ============================== ==================

    One way to use this report:
    proper levels of
    17-hydroxyprogesterone (17OH-P)
    can be manipulated by use of
    pregnenolone (first)
    and
    HCG injections (second)

    also
    measurements of 17-hydroxyprogesterone
    may tell us if we are using enough HCG.

    ////////////

    RESULT(S): With T administration alone, serum 17OH-P decreased significantly and increased significantly when 500 IU hCG was administered. End-of-treatment ITT strongly correlated with serum 17OH-P. Moreover, serum 17OH-P, but not androstenedione or DHEA, was independently associated with end-of-treatment ITT by multivariate linear regression.

    CONCLUSION(S): Serum 17OH-P is highly correlated with ITT in gonadotropin-suppressed normal men receiving T and stimulated with hCG. Serum 17OH-P is a surrogate biomarker of ITT and may be useful in research and in men receiving gonadotropin therapy for infertility.

    ////

    Group 3 (250iu)
    start-ITT=1239nmol/L
    end-ITT=1037nmol/L
    start-17-hydroxyprogesterone=4.9nmol/L
    end-17-hydroxyprogesterone=4.9nmol/L
    start-Androstenedione=6.4 (nmol/L)
    end-Androstenedione=6.6 (nmol/L)

    Group 4 (500iu)
    start-ITT=1227nmol/L
    end-ITT=1470nmol/L
    start-17-hydroxyprogesterone=4.6nmol/L
    end-17-hydroxyprogesterone=7.8nmol/L
    start-Androstenedione=6.5 (nmol/L)
    end-Androstenedione=9.5 (nmol/L)

    using Group 3 only to raise ITT to original levels requires HCG dose 250*1239/1037=299iu
    using Group 4 only to raise ITT to original levels requires HCG dose 500*1227/1470=417iu
    average(299,417)=358iu

    expect 17-hydroxyprogesterone to be at=6.3+(7.8-6.3)*(358-250)/(500-250)=6.9(nmol/L)=227.72 ng/dL

    expect Androstenedione to be at=8.4+(9.5-8.4)*(358-250)/(500-250)=8.9(nmol/L)=25.50 ng/dL












    3/16/2013


    HCG - 1000IU too much? - Page 2
    ----------------------------

    UPDATE: Very Low-Dose hCG & Intratesticular Testosterone

    UPDATE: Very Low-Dose hCG & Intratesticular Testosterone

    by Michael Scally MD





    ..........




    Serum 17-hydroxyprogesterone strongly correlat... [Fertil Steril. 2008] - PubMed - NCBI

    Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin.
    Attached Images Attached Images  

  13. Quote Originally Posted by JanSz View Post

    my Fibrinogen=424(175-425)
    LEF wants (180-250)
    I asked doc for TRENTAL®
    (pentoxifylline)
    Tablets, 400 mg
    1 or 2 tablets daily
    will see what comes out of this request

    Curcumin is supposed to do a job on fibrinogen. Do you have any experience with it?

  14. Quote Originally Posted by cpeil2 View Post
    Curcumin is supposed to do a job on fibrinogen. Do you have any experience with it?
    I was using Curcumin for a while but then stopped, newer done blood testing.

    LEF recomends Trental. Hopefully my doc will come thru.
    I will see him in an hour. (Good doc, I am able to contact him at will, to ease up on his time, few hour ago I send e-mail with my requests ).

    Inflammation (Chronic) - Print Version : Online Reference For Health Concerns

    Ok, Synthroid 25mcg
    and
    Pentoxifylli 400mg
    are at home.

    I am at 3.5 grains of Armour, that should put my FreeT3 at the top range
    but my freeT4 will lag behind hence 1pill 25mcg/day of Synthroid.
    I newer tried, I may be one of the lucky guys who convert T4-->T3
    Latter may want to get down on Armour and boost up Synthroid.

    Looking for a formula on how to do it.
    Assuming 3.5 Grains of Armour and 25mcg Synthroid keep FreeT3 and FreeT4 on top.
    Assuming that I am able to fully convert T3--->T3 how (without blood testing) figure my theoretical T4 dose that I would need in the basence of Armour.
    ============================== ============================== =========
    Nov9/07 For about 3 weeks I am using 3x25mcg Levothyroxin and 3Grains Armour divided in half.

    Normally I do not use Cortef but if I feel little down, and have dancing or gym ahead, I take one 5mg Cortef 2-3 hours before, sometimes another Cortef before I start dancing and feel much better and have better stamina.

  15. Quote Originally Posted by JanSz View Post

    What is the cheapest injectible fertility drug you can buy in the US?
    Question:
    What is the cheapest injectible fertility drug you can buy in the US? I have heard of quite a few different injectible drugs you can use (i.e., Pergonal, HMG, Humegon, etc) and want to know if there is a drug that is cheaper than the others and also is it effective?
    I recognize most of the drugs listed here as female fertility drugs. Do they also work to increase fertility in males?

  16. HCG works like LH (Luteinizing Hormone). LH in men controls testosterone release.

    HMG works like FSH (Follicular Stimulating Hormone). FSH in men triggers sperm production.

    There's less difference between male and female systems than you might think!

    Mark

  17. Quote Originally Posted by MarkLA View Post
    HCG works like LH (Luteinizing Hormone). LH in men controls testosterone release.

    HMG works like FSH (Follicular Stimulating Hormone). FSH in men triggers sperm production.

    There's less difference between male and female systems than you might think!
    That's very interesting. Which one does Clomid work on, FSH, right? My doctor says that boosting my clomid won't have any effect but I'm not sure about that.

    It sounds like what I need is the hCG, which is an IM injection, correct?

  18. Quote Originally Posted by hardasnails1973 View Post
    Jansz your going taking 3 steps backwards and one forward.
    what is dosage of testosterone you are taking every 3 days?
    The dosages you are doing are crossing the benefit/risk ratio of TRT and are headed into steroid usage which will only put stress on entire endocrine system and will feel good for 2-3 weeks untill your testosterone and estrogen receptors are over loaded and then you will crash. Been there did that done that. Your adrenals are already stress and adjusting your testosterone dosge to 800-900 on blood test on second day after the injection will give you a good average. Your e2 and DHT are going to go out the roof and like Dr Shippen told me using another drug inorder to offset side effects to push above the numbers all the way to high end is fuked up.

    Think of it this way
    bypossible swtiching over to hcg +injections and keeping them in upper 25% of the range you will lower dht and e2 which will reduce the need for finisterde and armidex. More is not better Bro and personally you are going to end up causing major cardiovascaular problems in the future tinkering around with those dosages. Go 42.5 mgs every 3 days with 250 ius retest in 4 weeks then increase if not into target range

    hardasnails

    i was wondering if you are a dr?also wondering where you get the basis for over 800-900 t level is unsafe. not breaking stones...just trying to understand.

    bodybuilders regularly have t levels of double or triple that and when on much higher.

    do you have any links / research that support what you are saying?

    bob

  19. Jan....thanks fo the B12 info

    Hardasnails....bump on the t question

    Bob
  20. rT3 high, how to deal with it


    Use thise three Genova diagnostics tests.

    Comprehensive Thyroid Assesment
    Oxidative Stress Panel (part of NutrEval)
    Elemental Analysis, Packed Erythrocytes (RBC's)(part of NutrEval)


    Read results, follow advice given by those tests.

    So really best would be to use two tests (few extra $$ but lots of informations):
    NutrEval
    Comprehensive Thyroid Assesment
    ---------------------------------------------------------------------------
    -------------------
    -------------------

    High rT3
    5' deiodinase (Se dependent)
    ----------------------------------------------------------
    Selenium also performs other important roles in the body.
    The most important of these is probably as its role as the body's best antioxidant (anti-peroxidant).
    It performs this role as part of glutathione peroxidase (GSHPx or GPX).

    Glutathione Peroxidase (GSH-Px)
    Glutathione peroxidase is a selenium-dependant enzyme found primarily in the cytoplasm (70%) but also in the mitochondria (30%).
    -----------------------------------------------------------------
    Genova Diagnostics' Oxidative Stress Panel
    checks Glutathione Peroxidase
    -----------------------------------------------------------------

    Interactions, (close): (iodine, selenium, zinc, copper)
    ie; at least above four have to be in proper balance
    ---------------------------------------------------------------------------------------------------
    Genova Diagnostics' Elemental Analysis, Packed Erythrocytes (RBC's)
    checks (it is missing iodine):
    TOXICS
    Antimony
    Arsenic
    Cadmium
    Lead
    Mercury
    Thallium
    Tin

    NUTRIENTS
    Chromium
    Copper
    Magnesium
    Manganese
    Potassium
    Selenium
    Vanadium
    Zinc

    ---------------------------------------------------------------------------------------------------
    If the above investigations falls short, further investigations should be made looking into:
    Interactions, (wide range)
    Ag, Co, Cr, Fe, Hg, I,Rb, Sb, Sc, Se, Zn



    -------------------------------------------------------------------------------------------------------------------------------
    http://www.ithyroid.com/iodine.htm
    While I've found research on the interactions of iodine and selenium, there are two other minerals which need to be studied for their interactions with these two: zinc and copper. I found one study which examined the complex interactions of selenium, iodine, and zinc (there are interactions), but none which have looked at all four minerals in a 4 X 4 factorial design. Now that would be an interesting study! Hopefully someone will do that soon.

    I think one lesson from studying the interactions of selenium and iodine is that the interrelationships between minerals are very complicated. Supplementing with one or two can cause further problems. You have to make sure that you correct every deficiency. Health is built from a chain of nutrients and, like a chain, health cannot be accomplished if one nutrient is missing. Sometimes it's complicated putting the chain back together without running into problems (like supplementing with either selenium or iodine, but not both), but every deficiency has to be corrected. John

  21. Blood test at Quest, blood drawn 3/19/2008
    page #1 --Comp metabolic panel
    page #2 --Hepatic function panel
    page #3 --CBC w/Diff , risk factors
    page #4 --
    page #5 -- VAP Cholesterol
    Attached Images Attached Images      

  22. Holy crap your iodine levels are off the chart.

  23. Quote Originally Posted by JanSz View Post
    Blood test at Quest, blood drawn 3/19/2008
    page #1 --Comp metabolic panel
    page #2 --Hepatic function panel
    page #3 --CBC w/Diff , risk factors
    page #4 --
    page #5 -- VAP Cholesterol
    E2 is too low, Jan, as I am sure you realize.
  24. rT3 high, how to deal with it


    rT3 high, how to deal with it


    Use thise three Genova diagnostics tests.

    Comprehensive Thyroid Assesment
    Oxidative Stress Panel (part of NutrEval)
    Elemental Analysis, Packed Erythrocytes (RBC's)(part of NutrEval)


    Read results, follow advice given by those tests.

    So really best would be to use two tests (few extra $$ but lots of informations):
    NutrEval
    Comprehensive Thyroid Assesment
    ---------------------------------------------------------------------------
    -------------------
    -------------------

    High rT3
    5' deiodinase (Se dependent)
    ----------------------------------------------------------
    Selenium also performs other important roles in the body.
    The most important of these is probably as its role as the body's best antioxidant (anti-peroxidant).
    It performs this role as part of glutathione peroxidase (GSHPx or GPX).

    Glutathione Peroxidase (GSH-Px)
    Glutathione peroxidase is a selenium-dependant enzyme found primarily in the cytoplasm (70%) but also in the mitochondria (30%).
    -----------------------------------------------------------------
    Genova Diagnostics' Oxidative Stress Panel
    checks Glutathione Peroxidase
    -----------------------------------------------------------------

    Interactions, (close): (iodine, selenium, zinc, copper)
    ie; at least above four have to be in proper balance
    ---------------------------------------------------------------------------------------------------
    Genova Diagnostics' Elemental Analysis, Packed Erythrocytes (RBC's)
    checks (it is missing iodine):
    TOXICS
    Antimony
    Arsenic
    Cadmium
    Lead
    Mercury
    Thallium
    Tin

    NUTRIENTS
    Chromium
    Copper
    Magnesium
    Manganese
    Potassium
    Selenium
    Vanadium
    Zinc

    ---------------------------------------------------------------------------------------------------
    If the above investigations falls short, further investigations should be made looking into:
    Interactions, (wide range)
    Ag, Co, Cr, Fe, Hg, I,Rb, Sb, Sc, Se, Zn



    -------------------------------------------------------------------------------------------------------------------------------
    http://www.ithyroid.com/iodine.htm
    While I've found research on the interactions of iodine and selenium, there are two other minerals which need to be studied for their interactions with these two: zinc and copper. I found one study which examined the complex interactions of selenium, iodine, and zinc (there are interactions), but none which have looked at all four minerals in a 4 X 4 factorial design. Now that would be an interesting study! Hopefully someone will do that soon.

    I think one lesson from studying the interactions of selenium and iodine is that the interrelationships between minerals are very complicated. Supplementing with one or two can cause further problems. You have to make sure that you correct every deficiency. Health is built from a chain of nutrients and, like a chain, health cannot be accomplished if one nutrient is missing. Sometimes it's complicated putting the chain back together without running into problems (like supplementing with either selenium or iodine, but not both), but every deficiency has to be corrected. John
  •   

      
     

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