A quote from Mike Arnold you may be interested in reading:
Liver stress due to oral steroid use has been greatly exagerated, especially in recent years. Whikle responsibility towards one's health is of paramount importance, not every preventative measure takenwith good intentions is always necessary. Limiting low-moderate dose D-bol cycles to 4 weeks for this reason is one of them. In reality, D-bol is one of the more mild oral AAS per effective dose, in terms of liver toxicity. Let's take Anadrol, for instance. For a long time Anadrol has been considered one of the more toxic oral AAS, but even with this drug, oral administration was conclusively proven by legitimate univeristy/government research to result in minimal liver stress even when dosed at 100 mg per day for 12 weeks. In one particular study, I believe 30+ test subjects used Anadrol for 12 weeks at 100 mg per day and at the conclusion of the study, only about 50% of the users (which included both men & women) experienced a degree of liver stress which was "concerning" to the medical examiners. They concluded that while liver tests indicated that liver markers were above what they considered to acceptable for longer-term use, the readings gave them no cause for alarm. The subjects did not require any medical intervention and recovered fully on their own without issue. The other 50% of the subjects had liver readings within an acceptable range, indicating that longer-term treatment was an option.
Remember, Anadrol was being developed primarily for anemia back at this time, long before the advent of EPO, and it was studied extensively. Afterwards, Anadrol became the go-to drug for the treatment of Anemia, being used by men, women, and children in doses up to 200 mg per day for many months straight. The use of this medication required regular doctor supervision to ensure that health markers remained in an adequate range, but overall this medicine was prescribed to 1000's of people across the U.S and elsewhere for decades. Taking into consideration the high-dose, long-term treatment commonly employed by these patients, how many cases of total liver failure leading to liver replacment do you think occured while this medication was being adminsitered under a doctor's supervision? The answer= ZERO!
Now, with Dianabol we are looking at a steroid with a much more favorable safety profile and a reduced toxic load per effective dose. While there is certainly the potential for harm with this drug, many indivduals have used this steroid for periods of 6-12 months at doses of 20-40 mg per day (and above) without any permament harm and undergoing a complete recovery without medical intervention. The percieved need to limit Dianbol cycles to 4 weeks or less, strictly when looking at the issue from a toxicity perspective, is not a physical need at all, but a psychological one. Dianabol can be safely used, pre-existing conditions aside, under normal circumstances for 10-12 weeks at commonly recommended doses. Running a very moderate cycle, such as 50 mg/day for 8 weeks, is a breeze for the liver, relatively speaking. In addition, with all the numerois and effective liver protection supps available on the market today, the need for concern is further dminished.
By far, the #1 health problem facing BB'rs today are cardiovascular health issues. Oral AAS are a primary contributer to this aspect of a BBr's health, but by taking the proper precautions to maintain proper lipid ratios, hematocrit levels, and blood pressure, we can greatly reduce the risk of these health probelms occuring.
Liver stress due to oral steroid use has been greatly exagerated, especially in recent years. Whikle responsibility towards one's health is of paramount importance, not every preventative measure takenwith good intentions is always necessary. Limiting low-moderate dose D-bol cycles to 4 weeks for this reason is one of them. In reality, D-bol is one of the more mild oral AAS per effective dose, in terms of liver toxicity. Let's take Anadrol, for instance. For a long time Anadrol has been considered one of the more toxic oral AAS, but even with this drug, oral administration was conclusively proven by legitimate univeristy/government research to result in minimal liver stress even when dosed at 100 mg per day for 12 weeks. In one particular study, I believe 30+ test subjects used Anadrol for 12 weeks at 100 mg per day and at the conclusion of the study, only about 50% of the users (which included both men & women) experienced a degree of liver stress which was "concerning" to the medical examiners. They concluded that while liver tests indicated that liver markers were above what they considered to acceptable for longer-term use, the readings gave them no cause for alarm. The subjects did not require any medical intervention and recovered fully on their own without issue. The other 50% of the subjects had liver readings within an acceptable range, indicating that longer-term treatment was an option.
Remember, Anadrol was being developed primarily for anemia back at this time, long before the advent of EPO, and it was studied extensively. Afterwards, Anadrol became the go-to drug for the treatment of Anemia, being used by men, women, and children in doses up to 200 mg per day for many months straight. The use of this medication required regular doctor supervision to ensure that health markers remained in an adequate range, but overall this medicine was prescribed to 1000's of people across the U.S and elsewhere for decades. Taking into consideration the high-dose, long-term treatment commonly employed by these patients, how many cases of total liver failure leading to liver replacment do you think occured while this medication was being adminsitered under a doctor's supervision? The answer= ZERO!
Now, with Dianabol we are looking at a steroid with a much more favorable safety profile and a reduced toxic load per effective dose. While there is certainly the potential for harm with this drug, many indivduals have used this steroid for periods of 6-12 months at doses of 20-40 mg per day (and above) without any permament harm and undergoing a complete recovery without medical intervention. The percieved need to limit Dianbol cycles to 4 weeks or less, strictly when looking at the issue from a toxicity perspective, is not a physical need at all, but a psychological one. Dianabol can be safely used, pre-existing conditions aside, under normal circumstances for 10-12 weeks at commonly recommended doses. Running a very moderate cycle, such as 50 mg/day for 8 weeks, is a breeze for the liver, relatively speaking. In addition, with all the numerois and effective liver protection supps available on the market today, the need for concern is further dminished.
By far, the #1 health problem facing BB'rs today are cardiovascular health issues. Oral AAS are a primary contributer to this aspect of a BBr's health, but by taking the proper precautions to maintain proper lipid ratios, hematocrit levels, and blood pressure, we can greatly reduce the risk of these health probelms occuring.