Klaus,
Yes, C17 additions necessarily enhance progestinic activity. 17b more so than 17a and ethyl more so than methyl. Propyl and ethinyl subs are decidedly progestinic with varying degrees of estrogenic activity. I am really probably not supposed to be discussing this without authorization, so when I say "we" you must make certain assumptions.
Yes, C17 additions necessarily enhance progestinic activity. 17b more so than 17a and ethyl more so than methyl. Propyl and ethinyl subs are decidedly progestinic with varying degrees of estrogenic activity. I am really probably not supposed to be discussing this without authorization, so when I say "we" you must make certain assumptions.