So worst-case scenario they pull NAC.
Perhaps we simply switch to using L-cystine:
Due to the ability of thiols to undergo redox reactions, cysteine and cysteinyl residues have
antioxidant properties. Its antioxidant properties are typically expressed in the tripeptide
glutathione, which occurs in humans and other organisms. The systemic availability of oral glutathione (GSH) is negligible; so it must be biosynthesized from its constituent amino acids, cysteine,
glycine, and
glutamic acid. While glutamic acid is usually sufficient because amino acid nitrogen is recycled through glutamate as an intermediary, dietary cysteine and glycine supplementation can improve synthesis of glutathione.
[13]
Yes from what I can find NAC is better at this vs l-cystine but perhaps we still have an option if we adjust dosing to overcome the issues with oxidation (and dimerization).
For those more in the know, can l-cystine be bonded to something else? I know ALRI used to make BCAA malates, I think it was their original Unchained???
Just spitballing possible ideas here.
Just switch to liposomal glutathione? Granted the price on this is high if I stick to brands I trust and avoid those sketchy amazon brands that for some reason always have three bottles in their picture, you guys/gals know the one's I'm talking about. lol
Alpha Lipoic Acid has been shown to increase GSH pretty reliably from some simple searching and is very inexpensive.
Good ole milk thistle:
The use of medicinal plants in treating illnesses has been reported since ancestral times. In the case of hepatic diseases, several species such as Silybum marianum, Phyllanthus niruri, and Panus giganteus (Berk.) have been shown to ameliorate hepatic ...
www.ncbi.nlm.nih.gov
"Silymarin enhances hepatic glutathione generation by elevating cysteine availability and inducing cysteine synthesis while inhibiting its catabolism to taurine. "