Look at it like this....There are NO studies I am aware of regarding arimistane and everyone uses it.
Look at the compounds being used aside from arimistane.
Do they have in- vivo, human, double blind placebo controlled studies? I know of one for example that is being used thats like a 500k- million times weaker than letro. Literally. And this is assuming it was 100% orally bioavailable which it almost certainly is not. Proof of viability is being based on a study claiming its so weak you would need to take like a kilo per day for it to work. The AI pool is shallow at the moment. Formestane was the last man standing.
The other issue is companies dont take the time or spend the money to study in house. We dont just take a reference in some obscure paper as proof of viability. We run extensive testing so we actually know if it works. This way we are not releasing a product and just hoping for the best and selling you guys something that has as much chance of being an AI as my shoe does. Its one thing to see something mentioned in a paper somewhere. Its another to prove it works. I dont think any intelligent human would assume something was viable based solely upon a single mention in a paper. Its a great start but you have to test for efficacy, dose, toxicity etc.
My point is there are a bunch of things being sold as AIs that have less supporting evidence than this.
I have studies showing=
% aromatase inhibition, as a whole plant and for the specific AI components within the plant.
Absorption
Metabolism
Toxicity
a host of other properties.
labs proving efficacy. Test increase, estro drop, LH,FSH, PRL, SHBG.
Well, for the sake of a good conversation allow me to address your points:
Ellagic Acid as a SERM can be placed in the same boat as Arimistane as an AI, being that there are no in-vivo, double blind, placebo controlled studies stating it has any effect on the HPTA in humans. Same with E. Cottoni. Furthermore being that E. Cottoni was shown to have comparable affinity to estrogen receptors as Tamoxifen, can you be sure its Ellagic Acid isnt being overpowered by E. Cottoni? I know you tested just ellagic acid and you support it, but it is arguable E. Cottoni has favorable data to support it being the stronger SERM of the two.
Again I would know, Ive seen the literature for both these ingredients. I am well versed with promegranate extracts(like Ellagic Acid for example) and there is more human data to support pom extracts vasorelaxation, oxygen free radical scavenging, hypolipidemic, and anti-inflammatory effects than its SERM abilities to modulate the HPTA favorably in humans(of which there is none). Furthermore I have seen the bloodwork of individuals on a test cycle whose estrogen was kept within normal range while test was through the roof, supporting that arimistane is an excellent choice for estrogen regulation. I even know an individual personally who ran test cyp and the OG erase and that was enough to control estorgen to prevent gyno(this individual was gyno prone). Don't be so hard on arimistane, I have personally found it to be quite effective.
Furthermore,I dont think its fair to assume other companies DONT conduct in house studies or internally test formula's/products as you alluded to.
For example, being a member of the R&D formulations team with OL I have personally witnessed and been part of researching, designing and in-house testing for what we release. So to make such an accusation is plainly unfair, if not false. I am sure other companies such as PES also do in-house testing to insure the final product to be top of the line. BLR is not the only company that makes sure their products have data on purity, metabolism, toxicity, absorption, % efficacy, etc etc. So to act as if BLR is unique in this endeavor is just not true, OL does this, and I am sure other companies do this as well.
Going back to the product at hand, I am quite eager to see what you ended up choosing and reading the data you have behind the product. As an avid researcher, my interest is always piqued by new products.
Exciting times, BLR releasing new products, we have at least 5 products on the horizon to be released shortly.
Did you read the article I posted by the way?
