Yes missing doses can increase sensitivity; you’re not keeping the overall levels as high. I use Ralox often when blasting now and also get high prolactin easily, and it runs on the higher side in general.
As mentioned by vinn, manage your estrogen and be taking something for prolactin often - if you are letting estrogen go higher you will need more aggressive prolactin control and a larger amount of Ralox. Something as simple as BLR’s Letrone and Prolactrone most of the time could help you lower your Ralox dose, or LOW doses of exemestane and Pramiplexole if you need more based on bloodwork. Cabergoline every 4-5 days is the secret weapon, but easily most costly. If you take something like a 19-Nor, that’s what you want on board if you are sensitive to prolactin. Mast, proviron, Rad140 are all good antagonists to run on cycle to compete for the estro receptors as well if you like any of them.
I generally try to save the pharmaceuticals for on cycle when I am disrupting things, and try to use natural things like DIM & P5P off cycle.