So when should I be dosing this bottle of agmatine that I just got? First thing in the AM before breakfast?I am unsure why all the references to supraspinal and IV admin.
There is an attenuation of total body agmatine stores as we age (pointed out in an article I did for Joey - then, CEO of MAN back with the launch of Blue Print). It may very well come down to younger individuals not benefiting as much as old. As for pre-workout administration; way back with the original launch for MAN Sports I did back in 2007/2008 and the product Blue Print...I have NEVER suggested this to be the time to dose it. I am uncertain how we have come to this really - possibly a lot of "me too" companies promoting it in this fashion (unsure); just as arginine and any other polyamine has shown - pre-workout is NOT the way to go and I maintain this position, now 5 years later!
Post-workout, on the other hand in combination with GABA might be exceedingly interesting.
D_