CEM Store
Board Sponsor
- Awards
- 1
IGF-1: The main factor for growth and repair in...
....the living animal.
IGF1? What is it, where does it come from and what are its actions in living cells?
If you have any questions like this then you will want to continue reading because the subject here is IGF-1 and there is A LOT to know about this wonderful peptide.
First things first, what is a peptide?
Peptides are similar to amino acids (protein molecules). A peptide is a short, large molecule of an amino acid molecule that can bind to other molecules to form a larger molecule and they are called a peptide or protein depending on their size. [1] IGF-1 is one of these ?Peptides? and is found in every living mammal. It comes from another peptide hormone called growth hormone. Growth hormone is broken down in the liver to IGF1 then makes its way into the blood stream.
IGF1 can have many functions in living animals, from repairing injury/burns to growing new tissue altogether. IGF1 plays a very important role in the living body and without it the body would just waste away. [2] IGF1 has been found in many studies to have a profound anabolic effect along with helping in the process of new tissue growth and that is of interest because this opens the door to many possibilities in the possible applications for IGF1.
So if it is found in the body and made in the liver from growth hormone[3], how could you use it for any application or even harvest it?
Well you see we have come a LONG way in science and now have the technology for make peptides using a method called peptide synthesis (recombinant dna) and can make as much as we need, while not needing to rely on animal extractions of this peptide.[4]
We at CEMproducts offer is only the highest quality synthesized IGF-1 peptide for your research needs.
I have already stated IGF-1 can help with repair and growth of new tissue, but how?
IGF-1 effects are mediated by binding to specific receptors like the Insulin-like growth factor 1 receptor(IGF1R). IGF1 receptors are present on many cells and in many tissues of the mammalian species. Binding to the IGF1R starts cellular signaling and IGF-1 is one of the most potent natural activators of the ?AKT signaling pathway?, a stimulator of cell growth and proliferation, and an inhibitor of programmed cell death. IGF-1 is also the primary cause for a lot of the effect you see with growth hormone (GH) in the body, making IGF1 one on the most sought after peptides on the market today!
IGF-1 stimulates growth, and has growth-promoting effects on almost every cell in the body, and a large part of it is skeletal muscle, cartilage, bone, organs (and skin), nerves and so on. The effects of IGF1 in the living animal are astounding and although IGF1 has some insulin-like effects in the body, it can also regulate cell growth and development and insulin would not have some of these effects hens the name ?insulin like growth factor? (IGF).[4]
As you can see, IGF-1 has a lot to offer in the research and development field and we at CEMproducts are proud to offer only the highest quality peptides for your research needs!
We hope you found this article useful. Check it out IGF-1 Lr3 (Lyophilized) 1mg
REF:
1) growth by somatomedin and other tissue growth factors Daughaday, William H. Clinics in Endocrinology and Metabolism (1977), 6(1), 117-35 CODEN: CEDMB2; ISSN: 0300-595X CAS Reference Linking Service
2) somatomedin activity. Part II: Biological effects in Snell dwarf mice International Congress Series (1980), 495(Growth Horm. Other Biol. Act. Pept.), 103-21 CODEN: EXMDA4; ISSN: 0531-5131 CAS Reference Linking Service
3) Endocrinology. 1976 Mar;98(3):606-14.Comparison of somatomedin activity in perfusates of normal and hypophysectomized rat livers with and without added growth hormone. Phillips LS, Herington AC, Karl IE, Daughaday WH. Comparison of somatomedin activity in perfusat... [Endocrinology. 1976] - PubMed - NCBI
4) BMC Biotechnol. 2011; 11: 37.Published online 2011 April 12. doi: 10.1186/1472-6750-11-37PMCID: PMC3098155 Glucose lowering effect of transgenic human insulin-like growth factor-I from rice: in vitro and in vivo studies Glucose lowering effect of transgenic human insulin-like growth factor-I from rice: in vitro and in vivo studies
....the living animal.
IGF1? What is it, where does it come from and what are its actions in living cells?
If you have any questions like this then you will want to continue reading because the subject here is IGF-1 and there is A LOT to know about this wonderful peptide.
First things first, what is a peptide?
Peptides are similar to amino acids (protein molecules). A peptide is a short, large molecule of an amino acid molecule that can bind to other molecules to form a larger molecule and they are called a peptide or protein depending on their size. [1] IGF-1 is one of these ?Peptides? and is found in every living mammal. It comes from another peptide hormone called growth hormone. Growth hormone is broken down in the liver to IGF1 then makes its way into the blood stream.
IGF1 can have many functions in living animals, from repairing injury/burns to growing new tissue altogether. IGF1 plays a very important role in the living body and without it the body would just waste away. [2] IGF1 has been found in many studies to have a profound anabolic effect along with helping in the process of new tissue growth and that is of interest because this opens the door to many possibilities in the possible applications for IGF1.
So if it is found in the body and made in the liver from growth hormone[3], how could you use it for any application or even harvest it?
Well you see we have come a LONG way in science and now have the technology for make peptides using a method called peptide synthesis (recombinant dna) and can make as much as we need, while not needing to rely on animal extractions of this peptide.[4]
We at CEMproducts offer is only the highest quality synthesized IGF-1 peptide for your research needs.
I have already stated IGF-1 can help with repair and growth of new tissue, but how?
IGF-1 effects are mediated by binding to specific receptors like the Insulin-like growth factor 1 receptor(IGF1R). IGF1 receptors are present on many cells and in many tissues of the mammalian species. Binding to the IGF1R starts cellular signaling and IGF-1 is one of the most potent natural activators of the ?AKT signaling pathway?, a stimulator of cell growth and proliferation, and an inhibitor of programmed cell death. IGF-1 is also the primary cause for a lot of the effect you see with growth hormone (GH) in the body, making IGF1 one on the most sought after peptides on the market today!
IGF-1 stimulates growth, and has growth-promoting effects on almost every cell in the body, and a large part of it is skeletal muscle, cartilage, bone, organs (and skin), nerves and so on. The effects of IGF1 in the living animal are astounding and although IGF1 has some insulin-like effects in the body, it can also regulate cell growth and development and insulin would not have some of these effects hens the name ?insulin like growth factor? (IGF).[4]
As you can see, IGF-1 has a lot to offer in the research and development field and we at CEMproducts are proud to offer only the highest quality peptides for your research needs!
We hope you found this article useful. Check it out IGF-1 Lr3 (Lyophilized) 1mg
REF:
1) growth by somatomedin and other tissue growth factors Daughaday, William H. Clinics in Endocrinology and Metabolism (1977), 6(1), 117-35 CODEN: CEDMB2; ISSN: 0300-595X CAS Reference Linking Service
2) somatomedin activity. Part II: Biological effects in Snell dwarf mice International Congress Series (1980), 495(Growth Horm. Other Biol. Act. Pept.), 103-21 CODEN: EXMDA4; ISSN: 0531-5131 CAS Reference Linking Service
3) Endocrinology. 1976 Mar;98(3):606-14.Comparison of somatomedin activity in perfusates of normal and hypophysectomized rat livers with and without added growth hormone. Phillips LS, Herington AC, Karl IE, Daughaday WH. Comparison of somatomedin activity in perfusat... [Endocrinology. 1976] - PubMed - NCBI
4) BMC Biotechnol. 2011; 11: 37.Published online 2011 April 12. doi: 10.1186/1472-6750-11-37PMCID: PMC3098155 Glucose lowering effect of transgenic human insulin-like growth factor-I from rice: in vitro and in vivo studies Glucose lowering effect of transgenic human insulin-like growth factor-I from rice: in vitro and in vivo studies
