Nice post on all counts, you're right about the SHBG factor when taken orally. Overall I believe it is more effective when used IM, also less stressful on the liver. I like Winny, a cheap great drug. When I use it I do 50/50 IM/orally.SHADOW2492 said:I could be entirely wrong here. But here goes anyway. It is a methylated steroid so can be taken orally and has probably the same absorbtion orally. BUT i have heard when taken orally it has a greater affinity for SHBG (sex hormone binding globulin) meaning it prevents testosterone from binding to it and keeps it in your blood. Giving you higher testosterone levels.
Also in the future I would advise to not put a request for a specific person to answer, as this may or may not be annoying to him/her, and it will actually detract people from coming in and answering who very well may know more or the same info as him. so what could happen is you end up not getting an answer because no one will click on it and the person who its addressed to will not see it because no answers and it gets dropped to the second page.
Thanks but, I was thinking I am not a biologist by any measure, but wouldnt it be doing the same damage, whether injected or not as it will pass through the liver either way?Alexander said:Nice post on all counts, you're right about the SHBG factor when taken orally. Overall I believe it is more effective when used IM, also less stressful on the liver. I like Winny, a cheap great drug. When I use it I do 50/50 IM/orally.
Skye said:just my two cents but....
Winny does not cause new cell growth regardless on how you take it. So far as I know no hormone outside of the IGF/HGH types do. Some hormones are believed to raise the body’s production of IGF but the route of administration isn’t going to affect that.
Winny is about 95% absorbed via ingestion. It is close to 100% via injection. That is the only real difference here. Injecting will provide a more even release then the oral but that is about it.
Winny MIGHT be slightly less toxic taken via inject based on the depot having a steadier release this not hitting the liver all at once. Outside of that there really shouldn't be any difference as the liver ends up processing it in the same matter as if you took it orally. The only difference is the release rate, and that you sidestep the first pass.
Skye said:just my two cents but....
Winny does not cause new cell growth regardless on how you take it. So far as I know no hormone outside of the IGF/HGH types do. Some hormones are believed to raise the body’s production of IGF but the route of administration isn’t going to affect that.
Winny is about 95% absorbed via ingestion. It is close to 100% via injection. That is the only real difference here. Injecting will provide a more even release then the oral but that is about it.
Winny MIGHT be slightly less toxic taken via inject based on the depot having a steadier release this not hitting the liver all at once. Outside of that there really shouldn't be any difference as the liver ends up processing it in the same matter as if you took it orally. The only difference is the release rate, and that you sidestep the first pass.
Skye said:Winny MIGHT be slightly less toxic taken via inject based on the depot having a steadier release this not hitting the liver all at once. Outside of that there really shouldn't be any difference as the liver ends up processing it in the same matter as if you took it orally. The only difference is the release rate, and that you sidestep the first pass.
Neither do I, at first I thought that if I had to guess I would say no, most 17a's are very dose dependent on how bad is stress your liver. So I would think that avoiding a sharp "spike" would be better. But then again some people have suggested that running an oral 5 days a week would reduce the stress on your liver so it could easily work the other way. Both points have merit so.....TeamSavage said:Some substances can actually be more toxic to the liver when exposure is steady and sustained (as in a depot) rather than periodic (as in an oral). Just depends on the substance. I have no idea if this applies to Winny... just something to consider.