Chip Douglas
Member
The first thing that comes to mind here is either primary or secondary hopgonadism/Kleinfelter. And while those can and will cause low T, and therefore low Dopamine, as T can increase DA, I'd like to get acquainted with the higher cause of low T as we age ?
Here I'm talking more on a molecular level i.e. aging is cause by the accumulation of free radicals, and glycation end products to large extent. These two latter terms emcompass a wide array of destructive reactions in the human body.
I know that Leydig cells become decrease or become less responsive as we age, so this is one reason T can go down for sure, BUT what causes the Leydig cells to decrease or to become less responsive to begin with ?
There's some underlying molecular mechanism at work here. Also what can be done to prevent this from happening ? I guess science hasn't yet eluciated how to stop or reverse this, but still, this would be an interesting discussion in this forum.
Cheers
Here I'm talking more on a molecular level i.e. aging is cause by the accumulation of free radicals, and glycation end products to large extent. These two latter terms emcompass a wide array of destructive reactions in the human body.
I know that Leydig cells become decrease or become less responsive as we age, so this is one reason T can go down for sure, BUT what causes the Leydig cells to decrease or to become less responsive to begin with ?
There's some underlying molecular mechanism at work here. Also what can be done to prevent this from happening ? I guess science hasn't yet eluciated how to stop or reverse this, but still, this would be an interesting discussion in this forum.
Cheers