I sometimes take them maybe half an hour before but most times at the same time, except if I'm taking three doses of orals in a day, then the middle dose is unaccompanied by a support supp.
We used to not take anything back a long time ago, but now I like this Ar1macare Pro stuff, which I take with an extra dose of tudca from another brand. Seems to work so far. Pretty sure it has what it says it has in it.
I load the tudca for a week before and then start the steroid and ar1macare.