Rocket3015
Legend
I hope you are kidding ???what about injectable liver support? I saw injectable glutathione on AA I think
I hope you are kidding ???what about injectable liver support? I saw injectable glutathione on AA I think
Invalid Link Removedwhat about injectable liver support? I saw injectable glutathione on AA I think
I mean, sure, it's an option but considering there's an array of oral liver support supplements proven to work well, I just don't see the need to bother with an injectable. My $.02.what about injectable liver support? I saw injectable glutathione on AA I think
I mean, sure, it's an option but considering there's an array of oral liver support supplements proven to work well, I just don't see the need to bother with an injectable. My $.02.
Wouldn't oral pass thru the liver better ???
It may, but realistically there is no issue with the absorption of the types that have been mentioned so its really a cost:benefit question more than anything... I just don't see it actually being much, if any, more effective (or cheaper) than the alternatives... If it were, you'd see more Dr.'s using it as well and that's not something I've literally ever heard.well the idea would be that an injectable is going to absorb better than oral. glutathione is available in oral form too. I probably would just run a vial every once in a while (once a year?)
It may, but realistically there is no issue with the absorption of the types that have been mentioned so its really a cost:benefit question more than anything... I just don't see it actually being much, if any, more effective (or cheaper) than the alternatives... If it were, you'd see more Dr.'s using it as well and that's not something I've literally ever heard.
Invalid Link Removed
Got a Great Deal! Thank you SNS.
Invalid Link Removed
Got a Great Deal! Thank you SNS.
I know this is an older thread but it’s not that old, and it has a good amount of quality responses… sooo..
why am I not seeing SAM-E mentioned at all? I know the hype from it died off as the efficacy of NAC and TUDCA were proven likely higher.
Any studies I’ve read support this- TUDCA/NAC as top tier in liver protection, but they also claim SAM-E to still be quite effective (which is why it was the go-to support for so long)- and some studies that even show the combo of SAM-E and TUDCA to be synergistic, providing even better protection. I’m not going to post them. If you want to look at studies just google it. The first page of results has everything I’m mentioning here.
so really I’m just wondering why SAM-E hasn’t been mentioned here in a list of the better products out there?
Good question and I'm glad to answer it from an industry perspective.
SAMe never really caught on nearly as much in bodybuilding circles as it did with the general health population. Although, and some may find this bit of trivia interesting - that Optimum Nutrition was one of the first companies to ever put a SAMe capsule out back when they used to do general health supplements as well.
There are probably 3 main reasons:
1. The way it works is not as applicable to bodybuilding as towards the general health consumer.
2. Quality, supply chain, and pricing issues have traditionally discouraged brands from making it.
3. The above 2 factors have discouraged brands from doing it so it hasn't been advertised in the bodybuilding community nearly as much as the general health side.
SAMe - Liver Support for the Bodybuilder vs. the General Health Consumer:
The way that SAMe works for liver support is by being a methyl donor and helping to restore glutathione levels in the liver and may also help support healing from liver injury. While this would also be good for the bodybuilder, these benefits are more applicable to other types of liver issues.
SAMe - Quality, Supply Chain, & Pricing Issues:
SAMe has always been fairly expensive as a single ingredient price and for many years had huge price and raw material quality fluctuations. There is also the issue with stability which for a long time made it hard to include in formulation items (along with the price). Most of the time consumers don't know things like this - but issues like this are a nightmare for reputable brands to deal with so it held them back and kept them from wanting to make or promote one.
^^^ so, while its a great ingredient, the above reasons kept it from catching on or being very popular in bodybuilding circles.
I've said in the past and always ranked it like this:
- Liver Assist XT (NAC, Milk Thistle, Artichoke, Curcumin) - for foundational liver support
- TUDCA - for advanced liver support
- SAMe - good for liver support & add it in if you have the above bases covered &/or want some of the extra benefits it provides
I hope this helps.
I am a fan of SAMe and had actually considered doing it as a single ingredient product or possibly using it in an upcoming formula (although it wouldn't be a liver support one).
I would encourage anyone using SAMe to make sure they're getting it from a reputable brand that has good quality controls. In my case, I prefer the NOW Foods brand for SAMe because I trust their quality.
That answer was incredibly better then what I was hoping and assuming I’d get. That all makes a lot of sense. I’m currently using TUDCA and SAMe, but am going to add NAC in too. I’ve used your liver assist before, and based on what it has/what I’m currently lacking, it looks like that’s the move right now. Thank you.
I know this is an older thread but it’s not that old, and it has a good amount of quality responses… sooo..
why am I not seeing SAM-E mentioned at all? I know the hype from it died off as the efficacy of NAC and TUDCA were proven likely higher.
Any studies I’ve read support this- TUDCA/NAC as top tier in liver protection, but they also claim SAM-E to still be quite effective (which is why it was the go-to support for so long)- and some studies that even show the combo of SAM-E and TUDCA to be synergistic, providing even better protection. I’m not going to post them. If you want to look at studies just google it. The first page of results has everything I’m mentioning here.
so really I’m just wondering why SAM-E hasn’t been mentioned here in a list of the better products out there?
Someone is always trying to take our hard earned money
But always putting it right back into bringing out more cool products to help people
I was speaking about these kind of sleez bags !!
A word of caution on TUDCA (not specific to you, just everyone) - be careful with the brand you get on this ingredient. In my opinion, its one of the top 5 most problematic ingredients in terms of raw material quality issues on the market. There are some brands that you will see, especially on Amazon, that claim to offer TUDCA at prices that are just simply impossible. I saw a brand on there the other day that if what they had were legit raws - if you took the cost of raw materials + bottle, capsule, lids, etc. and figured zero markup for their cm or the brand at all, that they would have been losing over 2.00 per unit when you figure in Amazon fees.
I was speaking about these kind of sleez bags !!
A word of caution on TUDCA (not specific to you, just everyone) - be careful with the brand you get on this ingredient. In my opinion, its one of the top 5 most problematic ingredients in terms of raw material quality issues on the market. There are some brands that you will see, especially on Amazon, that claim to offer TUDCA at prices that are just simply impossible. I saw a brand on there the other day that if what they had were legit raws - if you took the cost of raw materials + bottle, capsule, lids, etc. and figured zero markup for their cm or the brand at all, that they would have been losing over 2.00 per unit when you figure in Amazon fees.
That's awesomeA big reason why I buy Morphogen. You know you get exactly what you pay for.
Taking TUDCA from Ben has cut my liver enzymes in half with no other changes to my dietary habits or training schedule. Just simply add the product.
My AST was 91
ALT was 62
A few months on TUDCA
AST - 63
ALT - 41
A big reason why I buy Morphogen. You know you get exactly what you pay for.
Taking TUDCA from Ben has cut my liver enzymes in half with no other changes to my dietary habits or training schedule. Just simply add the product.
My AST was 91
ALT was 62
A few months on TUDCA
AST - 63
ALT - 41
Some people may remember, some may not, that under CEL we were one of the first companies to offer TUDCA as a supplement many years ago.
Hi everyone here I can tell you the best liver support supplements;
1. 1Md Liver MD.
2. Gundry MD.
These are the two best supplements for liver support that I use them.
Of the above listed, I like TUDCA/UDCA the best for the specific type of cholestatic injury bodybuilders do to their liver. But even a Cochrane Review wasn't so keen on it:
Invalid Link Removed
In second place would be milk thistle. But the only type of milk thistle that actually absorbs through the gut in significant quantities is the patented Siliphos type. And what's been disappointing is a study showing that while it reduced liver enzymes on a blood tests, when biopsies were done no histological changes in liver damage or disease was found with the milk thistle group.
And lastly there's NAC and glutathione, which are antioxidants and may help with chronic problems but only really proven in the case of an acute overdose. Glutathione is not absorbed by the gut it is broken down into it's amino acids first.
So I would think if you took Liver Assist XD and TUDCA you should be pretty good to go.
I'm not going to get into the Glutathione subject. There is too much commercialization and marketing on this subject both ways and debates usually only lead to arguments now days. All I'll say on this is that I think Milk Thistle, TUDCA, and NAC are all better options than it for liver support.
It's used for fatty livers. In fact if you inject it right into fat tissue it reduces the fat in the tissue so it's quite powerful. But also citicholine (CDP) and regular old choline gets converted to phosphotidylcholine. So do you really need the expensive hepatopro stuff? I don't know. But if you're going to take choline or choline derivatives for a fatty liver you might as well take inositol too.
So I would think if you took Liver Assist XT and TUDCA you should be pretty good to go.
What are your thoughts on PPC (polyenylphosphatidylcholine aka hepatopro)?
It's used for fatty livers. In fact if you inject it right into fat tissue it reduces the fat in the tissue so it's quite powerful. But also citicholine (CDP) and regular old choline gets converted to phosphotidylcholine. So do you really need the expensive hepatopro stuff? I don't know. But if you're going to take choline or choline derivatives for a fatty liver you might as well take inositol too.
Depends on the milk thistle/silymarin dose you think is necessary to work, which is debatable because it's debatable whether it even works in the first place. But, just my opinion here, I think if it works at all it is at a higher dose than most take, and for that you'll need the enhanced absorption Siliphos provides. Otherwise you're needing to take a whole lot of milk thistle caps.
Quercetin, on the other hand, is easy to overdose on and damage the kidneys. So those phytosomal or nanoparticle preparations haven't been recommended so much. We know it's not a good idea to take more than a gram of the regular stuff long term, we don't know how much for the advanced preparations. There is no similar concern with silymarin.
Nutriissa Cycle Support = Basically CEL Cycle Support compressive + TUDCA integrated, plus few things CEL doesn't even have.
You could literally buy a bottle of CEL Cycle Assist or SNS Liver Assist XT and a bottle of CEL TUDCA for around the same or lesser price than the product in the post and have the proper standardized extracts at their efficacious dosages.
The old school bodybuilders like to take what's called "MIC" for their livers which is Methionine, Inositol, Choline. They take it especially after a cycle to "clean out" fat and toxins. But as you correctly pointed out, SAM-e (S-Adenosyl methionine) is a better form of methionine without the homocysteine byproduct. But you can't trust all brands of SAM-e. And also citicholine/cdp-choline and phosphatidylcholine are better forms of choline. Alpha-GPC is too, but more geared for brain barrier entry and acetylcholine production. And if on a budget, plain old MIC is fine too. I wouldn't take it instead of TUDCA and milk thistle though.
TUDCA is something you can taste if you've tasted pure TUDCA before. It's probably the worst thing I've ever tasted. Some of those DMAA/DMHA powdered stims come close. As a bile salt you might think it would taste like poop but instead it's very chemically tasting and doesn't wash out of your mouth easily. So after buying a tub of the powder I quickly realized it needs to be capped. And even when capped you can taste any light residue on the outside of the capsules.
I'm sorry but no, it absolutely isn't.
We don't do window dressing products where we throw a little bit of everything but not hardly enough of anything into a product.
Specifying here - my post is not directed negatively at you; stuff like this pisses me off at the companies that do the shady crap like this that deceives people. So me addressing the product doesn't mean I'm putting you down in any way so please don't take it that way. I don't want to see you or anyone else get hurt by thinking they're taking the proper support type product when they aren't.
I most of the time don't comment on other companies products but you put me on the spot here where I can't in good conscience not reply to this bc this.
This is one of those types of products that is very deceptive to consumers and people that don't know exactly what they're looking for in terms of ingredients and extracts. Please don't take that wrong, I don't mean that offensively - I mean it in the sense that companies shouldn't try to use deceptive tactics to fool people into buying products.
As someone that works in the industry, when I look at this label what I see isn't necessarily what the customer sees. And that's the thing, I feel like a consumer shouldn't have to be super knowledgeable nor have to worry about being deceived by a label. And it can be especially bad and potentially dangerous in categories like this where people may be taking other things and relying on the product for support purposes.
Liver support is no joke, especially when taking methylated ph's.
Here are some things to look at pertaining to this product:
TUDCA - I already explained in this thread that TUDCA is one of the most underdosed and problematic raw materials on the market. I'm not saying this one is, I'm just saying people should be careful with TUDCA in general and make sure that they are buying from a reputable brand that tests each and every batch of raw materials.
Milk Thistle Powder - the active constituent in Milk Thistle is Silymarin. It's the Silymarin content that supports liver health, detoxification, and protection. This product literally has no Silymarin in it; therefore no active ingredient for liver health.
Glutathione - Glutathione is an odd ingredient choice for a product like this and especially at 40 mg. because that dosage is pretty useless. It's in here as a sales pitch and marketing tactic bc its a trending popular ingredient but there's not enough in here to do anything. Plus it doesn't specify that its a reduced form and if it isn't, its not the proper form for effectiveness anyway.
Hawthorn Berry Powder - this product contains Hawthorn Berry Powder, no standardized extract whatsoever - little to no active content.
Garlic - this product says Garlic Extract but doesn't mention Allicin and the dose is only 300 mg. So its dramatically underdosed to be a garlic supplement and there may be literally no Allicin and therefore no active content.
Saw Palmetto Powder - again, same trend as above. Powder, not extract. It does not specify any active constituent and acknowledges that its the basic herb powder - therefore little to no active constituent. In context, Natures Herbs had a Saw Palmetto powder dosed at I believe 700 mg. and they considered the effective dose 9 capsules per day!
Biotin - two issues here that make me wonder what is even going on with this product - 1) Biotin is supposed to be dosed in mg. or mcg, not in IU's. 2) Biotin is supposed to be identified at the top of the label with the Vitamins and minerals; not at the bottom of the label like this. (and on that subject, Bioperine is supposed to NOT be in the top of the label with the vitamins).
I never nitpick companies on label typos or things like that bc mistakes and accidents can happen - but in today's times of stricter FDA compliance and GMP guidelines, its crazy to me that a company doesn't know or doesn't even care to at least seemingly label their product in a compliant legal manner.
As for your comparison to Cycle Assist:
Per Daily Dose:
Milk Thistle:
- Product in your post - 1000 mg. of Milk Thistle Powder (no Silymarin specified)
- Cycle Assist - 1000 mg. Milk Thistle Extract (Std. to 80% Silymarin)
Hawthorn:
- Product in your post - 1,000 mg. Hawthorn Berry Powder
- Cycle Assist - 900 mg. Hawthorn Berry Extract (Std. to min. 1.8% Vitexin)
Saw Palmetto:
- Product in your post - 1,000 mg. Herb Powder
- Cycle Assist - 320 mg. Saw Palmetto Extract (std. to min 45% fatty acids)
Cycle Assist also contains 150 mg. per day of Celery Seed Extract and 150 mg. per day of Grape Seed Extract.
We actually address the problem with non-standardized herbs in the Cycle Assist write up. Here's a link for anyone that wants to read it:
https://competitiveedgelabs.com/product/cycle-assist/
You could literally buy a bottle of CEL Cycle Assist or SNS Liver Assist XT and a bottle of CEL TUDCA for around the same or lesser price than the product in the post and have the proper standardized extracts at their efficacious dosages.
Why does my cycle assist have ALA and apigenin in it now?
thanks for your advice