What is P5P and why do I need it?

MySTeek

MySTeek

Active member
Vit B6 (as Pyridoxal-5-Phosphate)

Overview:
P-5-P is the most active form of vitamin B6, having significant nootropic effects. P-5-P plays an essential part in mood, memory formation, and executive functions.

Scientific Name:
(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl phosphate

Mechanisms:

Essential for cellular energy metabolism[1]
Increases mental and physical energy, improves neuronal communication[2]
Prevents age-associated neuronal damage[3]
Involved in the synthesis of acetylcholine, dopamine, serotonin, noradrenaline and melatonin[4,5]
Important role in executive functions, memory formation, mood regulation, focus, motivation, and sleep regulation[5,6]
More Info:

Intro: Invalid Link Removed
Studies: Invalid Link Removed

Articles: Invalid Link Removed

References

[1] Clayton PT (2006). B6-responsive disorders: a model of vitamin dependency. J Inherit Metab Dis, 29(2-3):317-26. doi: 10.1007/s10545-005-0243-2
[2] Ebadi M, et al (1990). Hippocampal zinc thionein and pyridoxal phosphate modulate synaptic functions. Ann N Y Acad Sci, 585:189-201. doi: 10.1111/j.1749-6632.1990.tb28053.x
[3] Campanini B, et al (2013). Serine racemase: a key player in neuron activity and in neuropathologies. Front Biosci (Landmark Ed), 18:1112-28. doi: 10.2741/4167
[4] Yoshimura T, Goto M (2008). D-amino acids in the brain: structure and function of pyridoxal phosphate-dependent amino acid racemases. FEBS J, 275(14):3527-37. doi: 10.1111/j.1742-4658.2008.06516.x
[5] Deijen JB et al (1992). Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Psychopharmacology (Berl), 109(4):489-96. doi: 10.1007/BF02247729
[6] Ebadi M (1981). Regulation and function of pyridoxal phosphate in CNS. Neurochem Int ;3(3-4):181-205. doi: 10.1016/0197-0186(81)90001-2
Click to expand...

Source: Invalid Link Removed

Where do you get it? Millennium Sport Technologies already figured it out for you. The following list of MST goodies contain P5P and all their glorious nootropics potential!

1. Electrolytes!
Invalid Link Removed

2. King of multivitamins!
Invalid Link Removed

3. The ultimate Dream and Cognitive enhancer!
Invalid Link Removed

All-together and on their own, they make for a very wise choice. Go eat your veggies and take your B vitamins!
ryanp81 thank you for the reminder!
 
Interesting, I'll be making room for MVP once I'm free of other obligations. ;)
 
You must log in or register to reply here.
Back
Top