Are you guys interested?
Why Would this Product be Different?
Hi, guys. Would anyone here be interested in a sterile, oil-based version of Ursolic acid? Unlike the typical 1-2% bioavailability found with regular Ursolic acid, this product would be roughly 50-100X more potent, per mg. Each serving would probably be 100 mg per dose, which is the equivalent of roughly 5,000-10,000 mg when using normal oral formulations. Even though transdermal versions have much higher bioavailability than oral versions, they are still very, very low in comparison to the type of product I am talking about. For the first time, we would be able to harness the full power of Ursolic acid to build muscle and burn fat.Why Would this Product be Different?
The primary issue associated with Ursolic acid is its very poor solubility. This makes absorption incredibly difficult. In fact, it is so bad that it can't even be made into an effective, sterile, oil-based product. It's solubility in ethanol is only .5-1 mg per ml in pure ethanol. But, injectable products are normally only comprised of only 2% ethanol, thereby making an efficaciously dosed product impossible. That's worse than oral versions, as at least oral versions can be dosed as high as someone wants, while injectable versions are limited to the amount of Ursolic acid that can be dissolved into 1/100th to 1/200th ml of ethanol. Regardless, both versions suck.
The only way to make a truly effective Ursolic acid product is to drastically increase its solubility. The good news is that we now have the technology to do so; to the point where it is 100% dissolvable even in water! This still doesn't completely overcome the oral bioavailability issues, but it does increase its oral bioavailability by around 400-450%. This makes an oral version feasible, as it would allow the individual to cost-effectively use the product orally.
But where this new version of Ursolic acid really shines is with sterile-oil-based products! A full 100 mg of Ursolic acid can be dissolved into just 1 ml of your typical oil-based product. As mentioned above, that would be like swallowing 5,000-10,000 mg of Ursolic acid with each serving. Now that is a truly effective dose, especially since Ursolic acid's effects have been shown to be dose-dependent!
But...what if I upped the ante even further and combined Ursolic acid with another truly effective, but up to this point, under-utilized ingredient? I am talking about 7-Keto DHEA; another ingredient which showed great promise in research trials, but which failed miserably on the supplement market due to, once again, extremely poor oral bioavailability. Like Ursolic acid, 7-Keto DHEA's oral bioavailability is only 1-2%. This means that the typical oral dose of 200 mg yielded only 2-4 mg of useable 7-Keto DHEA. That is just NOT enough to provide the impressive effects on fat loss that researchers noted in their trials with injectable preparations.
I Want to Hear Your Recommendations!
Aside from Ursolic acid and 7-Keto DHEA, what other ingredients have you guys encountered over the years that showed great promise, but simply couldn't be made effectively due to a lack of bioavailability? If you have any suggestions, please fire away. Thanks.
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