If youre otherwise healthy then there is probably nothing acutely dangerous or unhealthy. Generally speaking, what makes supraphysiological levels like that dangerous is when these type of levels are sustained for longer periods. Or, the more often you have supraphysiological hormone levels, the greater the health risk (ie burden on the heart/CV system).
A supraphysiological level would likely only be acutely dangerous if you had some pre-existing condition or unnormal susceptibility. Otherwise, the danger to health would, again, be accumultive with use/exposure. How long til you hit the danger period? No way to foretell, as it would depend on the actual doses, the compounds, your particular reactions and biological makeup, genes, etc etc.