In my last cycle I ran them together, 400mg NPP/week and 600mg tren enanthate a week. Didnt really seem to have any problems, also added in anadrol at 100mg/day and that did make the nips pretty puffy, B6 kept it somewhat in check. I was also taking dostinex @ 0.5mg e4d, honestly didnt notice much from it, or anything at all. Sex drive was still alright, not super like on test, but everything still worked fine. I liked combining them together, the only thing I did notice was the NPP made me really lethargic, it was worse than when I tried M1T, after stopping the NPP my energy levels came back after a week.