There has always been the Clomid vs. Nolva debate. My personal bloodwork has shown higher test levels every time using Clomid 50/50/25/25 vs. Nolva 20/20/10/10. Not majorly higher levels, but higher nonetheless. IMO both are very effective at HPTA stimulation and have their own pros and cons. Intriguing argument for Nolva though. Care to cite the scientific sources for your claims?
I'm going to chime in on the dose mg argument. So the mg vs. mg argument is not valid on any drug. For instance. People dose tylenol at nearly a gram all the time, but some people use Aleve in the sub half gram levels with better results. Some still prefer tylenol. That's just an example and perhaps a poor one but it's a common example.
The idea that a drug is more effective because it is used at lower milligrams just isn't true. Is it more effective by weight? Sure, but receptor binding affinity, liver enzyme pathway and drug half-life are really more important than the dose. Is it more effective even after being dosed at the recommended mg/kg level the lab that made it lists? Are mushrooms more effective than LSD considering the active dose is like 2mg in a mushroom and like 150mcg for acid? No not at all, they're apples and oranges.
The question you want: "Is this drug MORE effective than this other drug when I dose both at the set dosages".
You can always look at upping the dose of the less effective drug, but you run closer to the OD level, strain the liver more (and perhaps that effect nullifies any benefit to increasing the dose vs taking another drug), and generally it runs contrary to the medical research done by the labs.
Another huge consideration to that, "can the user handle the sides at this dose of whatever drug"? If yes great! If no then perhaps the slightly less effective drug is actually better (again at the recommended dose).
Finally if you have taken both compounds, neither work great but you've already maxed the recommended dose you can ask "can I stack it with the other at a reduced dose for both". This works great with a lot of things (I have done Nolva and clomid this PCT at 12.5/12.5 each with no sides from either) and terrible at other combinations that would just compete over receptors. Some drugs can act synergistically, actually amplifying the effects of both at much lower doses.
This concept leads people to take way less or way more of a compound than they should. Every drug has an acute OD level, and a chronic abuse level. That level is different in mg/kg for every drug! Some drugs are closer to that level at the recommended dose than others. And that's not necessarily proportionally closer or further away.
There has to be a thousand compounds out there that dose higher than others and are either more or less effective than drugs dosed at different levels. Realistically the drug is produced to elicit an effect, once it's shown to do that they work out how much you need to take to get that effect. Then the dose is set. The weight vs effectiveness ratio (if you will) is meaningless if you can take some drugs in the gram level and others in the microgram level and get the listed effect. Think trying to take a methyl substance rated at 15mg in the range of a non methy 500mg+ level. But if they're both effective at the respective levels, if both binds to androgen receptors, which is more "effective"? You gotta consider all that other stuff, sides, total dose vs actual effect, half life, load on the liver, etc..
