Its a time related thing unique to every individual. If you are putting more into your body than it naturally produces, over time, it will cause the hpta to send signals to the brain to shut off that production because it doesnt need to do it anynore. This happens even to men on low dosage of TRT as little as 100mg a week. For trt, we usually see this shutdown roughly 5-10 months after beginning.
This is similar to why you have to change your workout structure every so often or the excersises that you do. The body adapts and evolves to its given circumsrances.
Now, granted that say your body manufactures 100mg a week (crude measurement for inside body, but point remains the same) and your putting in 50mg a week, it will continue to produce, but it will evolve to only producing half its normal workload.