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The Official OL UK Cardar1ne Q&A

vujade said:
Heres the thing, a lot of things that are taken in high doses can cause cancer.

Acetametaphen, the ingredient in Tylonol was found to cause cancer in higher doses.

Human studies were done by GSK even after the Rats were found to get cancer..
Healthy & Sick humans were tested up to 12 weeks as high as 10mg per day with no ill effects.

Mice did not get cancer. Mice are closer in genetics to us, then Rats.
Rhesus Monkeys did not get cancer.
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Which is what I had stated in an earlier post, if cancer was a concern then studies never would have gone forward to human trials.
 
Hastur said:
I personally wouldn't recommend taking Cardar1ne at night, there have been more than a few reports that taking it close to bed affects sleep quality. Of course this is highly individual, but I had no issues taking it on an empty stomach pre-morning cardio. I recommend playing with the dosage and seeing what works for you, with a 24h half life, timing shouldn't be a great concern.
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Okay, thanks.

Morning definitely suits better...was just curious about the absorption with pre-workout fasted dosing.

Will take pre and see.
 
Shin Sprints said:
Okay, thanks.

Morning definitely suits better...was just curious about the absorption with pre-workout fasted dosing.

Will take pre and see.
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Hey, we all have different schedules, goals, so on. I understand trying to find the optimal dosing time and making it mesh with my personal schedule. I'm an empty stomach morning cardio kind of guy, so I've had to be flexible with timing on certain things. Trial and error is a necessary evil with most supplements, but once you find what works for you, it should be smooth sailing. Like I said, morning worked for you, and if it suits you better, definitely start there. The absorption shouldn't be an issue with its high bioavailability and long half life. And earlier dosage ensures less likely-hood of sleep disruption that a small number of people have commented on with evening dosing. So give it a shot, and let us know how it works out for you!
 
It seems to be 50/50 on affecting sleep from what I've seen/read. Some users experience no issue with sleep, some do. It's all down to your own body and only you know it best of course :)

Basically just echoing what hastur said I guess lol
 
Cogy said:
No trouble sleeping on 2 caps a day.
When does endurance boost kicks in ?
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Glad you experience no sleep issues! Some report immediate endurance increases, others it seems to take a few days to notice. Of course, it depends on what activities you aee engaged in. You'll notice the endurance more if you're a distance runner versus a low rep, high weight lifter.
 
Hastur said:
Absolutely spot on, and echoes my sentiments on all levels. Well put, my friend.
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For a COX-2 inhibitor it is recommended to use "trib"...is that tribulus or tribulus terrestris? Is there a difference between the two? also would you recommend trib or curcumin? What are the benefits between the two?
 
thu_hobbit said:
For a COX-2 inhibitor it is recommended to use "trib"...is that tribulus or tribulus terrestris? Is there a difference between the two? also would you recommend trib or curcumin? What are the benefits between the two?
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Trib is referring to Tribulus Terrestris (same as tribulus....typically). There ARE a few types of tribulus out there, but for purposes of COX-2 inhibition the most common form, Tribulus Terrestris, works just fine.
 
kboxer7 said:
Trib is referring to Tribulus Terrestris (same as tribulus....typically). There ARE a few types of tribulus out there, but for purposes of COX-2 inhibition the most common form, Tribulus Terrestris, works just fine.
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Thats what i figured. I was looking at TribX90. They claim to have 90% furastanolic saponins such as protodioscins, diosgenins, flavonoids, and alkaloids. Anybody tried this yet? If not whats a good brand trib and a good daily dosage
 
thu_hobbit said:
For a COX-2 inhibitor it is recommended to use "trib"...is that tribulus or tribulus terrestris? Is there a difference between the two? also would you recommend trib or curcumin? What are the benefits between the two?
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Trib is Tribulus Terrestris, and really, the only heavily marketed Tribulus there is. There are other plants with the name Tribulus ____, but for the sake of this conversation, they are inconsequential. There are too many benefits to list regarding Curcumin, but yes, you could absolutely use both! No negative interactions whatsoever! In fact, for general health, I'd recommend eating curry/turmeric for the curcumin content on a daily basis. Take a look, the data out there is immense. Far too much for me to cover!

kboxer7 said:
Trib is referring to Tribulus Terrestris (same as tribulus....typically). There ARE a few types of tribulus out there, but for purposes of COX-2 inhibition the most common form, Tribulus Terrestris, works just fine.
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Mhmm, spot on!
 
thu_hobbit said:
Thats what i figured. I was looking at TribX90. They claim to have 90% furastanolic saponins such as protodioscins, diosgenins, flavonoids, and alkaloids. Anybody tried this yet? If not whats a good brand trib and a good daily dosage
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You don't have to get fancy, literally any Tribulus extract will get the job done, just use the lowest dosage recommended on the bottle, and you're good to go. I assure you. Don't pay too much, and don't overthink it!
 
Hastur said:
You don't have to get fancy, literally any Tribulus extract will get the job done, just use the lowest dosage recommended on the bottle, and you're good to go. I assure you. Don't pay too much, and don't overthink it!
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While this may be true when it comes to using Trib as Cox-2 inhibitor, but it does not apply when it comes
to using a tried and true trip product that has a high percentage of protodioscins & steroidal saponins.
 
vujade said:
While this may be true when it comes to using Trib as Cox-2 inhibitor, but it does not apply when it comes
to using a tried and true trip product that has a high percentage of protodioscins & steroidal saponins.
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Well, I was only advocating it as a COX-2 inhibitor. For the purposes of this thread, and the subject being Cardar1ne, I am only concerned with recommending Tribulus Terrestris as a COX-2 inhibitor. Other facts regarding it could definitely fill its own thread, and in fact, has done so with many in the past when Tribulus had its 15-minutes of fame way back when.
 
So any trib works? I was reading that you should only use trib if it has at least 40% protodioscins otherwise its basically a ripoff
 
thu_hobbit said:
So any trib works? I was reading that you should only use trib if it has at least 40% protodioscins otherwise its basically a ripoff
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For purposes of COX-2 inhibition that is not a concern. Any standard run of the mill tribulus will work just fine for what you need it for. Just buy from a legit brand.
 
kboxer7 said:
For purposes of COX-2 inhibition that is not a concern. Any standard run of the mill tribulus will work just fine for what you need it for. Just buy from a legit brand.
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Exactly. The recommendations regarding standardization and whatnot have to do with the supposed anabolic benefits of Tribulus that never manifested in the real world.
 
vujade said:
While this may be true when it comes to using Trib as Cox-2 inhibitor, but it does not apply when it comes
to using a tried and true trip product that has a high percentage of protodioscins & steroidal saponins.
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Hastur said:
Well, I was only advocating it as a COX-2 inhibitor. For the purposes of this thread, and the subject being Cardar1ne, I am only concerned with recommending Tribulus Terrestris as a COX-2 inhibitor. Other facts regarding it could definitely fill its own thread, and in fact, has done so with many in the past when Tribulus had its 15-minutes of fame way back when.
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I should have clarified my statement. What i was trying to say was this...

but it does not apply when it comes to using a tried and true trib product that has a high percentage of
protodioscins & steroidal saponins when Trib is being used to boost LH, as you might do in PCT.

I wasn't trying to derail the conversation. I just didn't want potential newbies to think that you could use
any old Trib product for boosting LH, like it would be for inhibiting Cox-2. Thats what gave Trib a bad
name in the 1st place. Too many Trib products with little to no protodioscins.
 
vujade said:
I should have clarified my statement. What i was trying to say was this...

but it does not apply when it comes to using a tried and true trib product that has a high percentage of
protodioscins & steroidal saponins when Trib is being used to boost LH, as you might do in PCT.

I wasn't trying to derail the conversation. I just didn't want potential newbies to think that you could use
any old Trib product for boosting LH, like it would be for inhibiting Cox-2. Thats what gave Trib a bad
name in the 1st place. Too many Trib products with little to no protodioscins.
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Ahh, I see. I fully understand where you're coming from now, vujade! My PCT will include Cardar1ne and Tribulus Terrestris, so the boost in LH will be quite welcome. :)
 
thu_hobbit said:
Awesome guys thanks for the quick and informative replies.
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Absolutely, anytime! If you have any more questions in you future, you know where you bring them! And feel free to PM me with questions about Cardar1ne or any other Olympus UK product, I am more than happy to respond as quickly as possible! :)
 
Hastur said:
Absolutely, anytime! If you have any more questions in you future, you know where you bring them! And feel free to PM me with questions about Cardar1ne or any other Olympus UK product, I am more than happy to respond as quickly as possible! :)
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Thanks man. I definately will
 
UPDATE:

1) yesterday (Sun., August 16th) was day 26, day 19 @ 21mg.

2) yesterday was my strength circuit. I was feeling like I was about maxed out at 21 Min. for this 20 set workout. Well, I completely blew past it with 18 Min.! That's a 14% decrease in a time I thought was at, or near, my max.! That includes the change-over between the 5 rep sets and the 3 rep sets.

3) yesterday I REALLY felt the endurance kick in. Not only that, I was very strong and explosive as well. It was really noticeable, unmistakable in fact! What strikes me as strange, is that I've been on Cardarine for almost 4 weeks.

Has anyone heard of Cardarine taking this long to kick in? Keep in mind that I'm kind of a low rep trainer, for the most part.
 
I'm at about the same timeframe. Dosing has been 21 mg for about 10 days now. I am just now 20 days in feeling some effects in endurance but not the fat loss effects yet. Seems to be finally kicking in though.
 
As mentioned before definitely feeling the endurance. Not so much on the fat loss though. I am also about 30 days in.
 
Second time cycling cardarine, but today was my first day on OL brand

took 3 caps today - I noticed I lasted longer in sauna than normal. I will keep an eye on vO2 max. could be placebo- will try this again and test later, and a few more times for more accurate review.

I will be doing cardio everyday on this supplement.
 
It's interesting people are reporting it takes a while to kick in, or be noticeable. This contradicts earlier reports I've seen and read. I suppose you could chalk it up to being highly individual, but know knows how many variables come into play here.
 
Hastur said:
It's interesting people are reporting it takes a while to kick in, or be noticeable. This contradicts earlier reports I've seen and read. I suppose you could chalk it up to being highly individual, but know knows how many variables come into play here.
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Yeah, I felt it a little quite quick, but it has taken weeks for it to really kick in.
 
crowbar46 said:
Yeah, I felt it a little quite quick, but it has taken weeks for it to really kick in.
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This is very interesting. So, while obviously stacking other compounds, how might you describe the endurance and fat loss effects on Cardar1ne?
 
Hastur said:
It's interesting people are reporting it takes a while to kick in, or be noticeable. This contradicts earlier reports I've seen and read. I suppose you could chalk it up to being highly individual, but know knows how many variables come into play here.
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I believe it kicked in for me after about 5 days at 7mg.

This is my second day at 14mg (Start of Week 2).

When I say "kicked in" I feel cardio endurance is definitely improving and I am pretty cardio fit so not starting at a low base level where improvements are easier to come by.

Can't say I have noticed much on fat loss front.
 
Shin Sprints said:
I believe it kicked in for me after about 5 days at 7mg.

This is my second day at 14mg (Start of Week 2).

When I say "kicked in" I feel cardio endurance is definitely improving and I am pretty cardio fit so not starting at a low base level where improvements are easier to come by.

Can't say I have noticed much on fat loss front.
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Excellent anecdotal reports, Shin Splints! Somehow by your name, I figured you might be pretty into cardiovascular fitness. ;) I hope you notice more fat loss with time, some report extreme differences, others more mild it seems. I wonder if it has to do with where they are at baseline regarding their genes and PPAR.
 
Hastur said:
This is very interesting. So, while obviously stacking other compounds, how might you describe the endurance and fat loss effects on Cardar1ne?
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Well, endurance manifested for me during my strength circuits. Here's my set-up for that workout right now:

1a) Dead/squat:

305 Lbs. X 5, X 5; 325 Lbs. X 3, X 3

2a) D.B. incline bench press:

85 Lbs. X 5, X 5; 90 Lbs. X 3, X 3

3a) Snatch-Grip High Pulls:

145Lbs. X 5, X 5; 165 Lbs. X 3, X 3

4a) D.B. alternating shoulder press:

60 Lbs. X 5, X 5; 65 Lbs. X 3, X 3

5a) pronated lat pulldowns:

190 Lbs. X 5, X5; 200 Lbs. X 3, X 3

So, this is performed in circuit fashion for time. I was going to progress the weight by 10-20 Lbs. on each movement when I could get my time under 20 Min. The last two circuit workouts (I perform this strength circuit once/week) I was stuck at 21 Min. And thought that I was maxed out for time with those weights. Then this last Sunday I blasted past that with 18 Min.! I was strong and explosive as well. That's a 14% decrease in a time I thought was my max!

I felt unstoppable, recovering more fully between sets with very little rest--just the time it takes me to get to my next station. After my training I also felt I recovered faster and was fresher, less drained.

Fat loss has been accelerated also, however, honestly, it's impossible to determine the relative contribution of the Cardarine and Gharine. I've reduced calories and carbs, as well as added a 45 Min. morning walk 3 x week, semi fasted (on an empty stomach, where I drink a partial Biotest Mag-10 @ 15 and 30 Min. into the walk.).
 
AndrewMcD said:
I workout around noon. I just received Cardar1ne in the mail yesterday.
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I believe it has a 24 hour half life so taking in the morning and working out later shouldn't be an issue.

I think some people dose in the morning as later in the day can cause sleep issues in some but taking pre-midday workout unlikely to cause you sleep issues as it would still be quite early in the day.

I suspect dose at whatever time is convenient, I don't think there will be a performance impact...my two cents.
 
So I'm about to start and am curious about what dose timing would make sense for me... I lift first thing in the morning, but don't usually eat anyhting until at least mid afternoon (usually a shake), followed by most of my cals/food in the evening.... My concern with taking the dose pre is that the long fast afterwards could cause (as reported by a few here) low blood sugar issues... The wa I was thinking was splitting the dose, 1 cap pre, 1 cap eve which would hopefully negate both the potential low blood sugar issues as well as sleep issues. Thoughts?
 
booneman77 said:
So I'm about to start and am curious about what dose timing would make sense for me... I lift first thing in the morning, but don't usually eat anyhting until at least mid afternoon (usually a shake), followed by most of my cals/food in the evening.... My concern with taking the dose pre is that the long fast afterwards could cause (as reported by a few here) low blood sugar issues... The wa I was thinking was splitting the dose, 1 cap pre, 1 cap eve which would hopefully negate both the potential low blood sugar issues as well as sleep issues. Thoughts?
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I'm similar to you with a Long fast but I train later in the day/early evening. I haven't used it yet but my plan is the same.. 1 cap about an hour pre and another cap basically post workout similar to GDA style dosing .. Try it out and adjust accordingly if needed
 
I´m on the last weeks on my lgd/epiandro run and I´ve just started up my Cardarine run. Will run it through the whole PCT.
 
booneman77 said:
So I'm about to start and am curious about what dose timing would make sense for me... I lift first thing in the morning, but don't usually eat anyhting until at least mid afternoon (usually a shake), followed by most of my cals/food in the evening.... My concern with taking the dose pre is that the long fast afterwards could cause (as reported by a few here) low blood sugar issues... The wa I was thinking was splitting the dose, 1 cap pre, 1 cap eve which would hopefully negate both the potential low blood sugar issues as well as sleep issues. Thoughts?
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It has a 24 hour half life, and with it lowering blood sugar, I'd take it with a meal containing carbs. You can take it at any time, and it will be effective, as it's not the type of supplement you take 30-minutes pre-workout or anything like that. Something I wouldn't advocate anyways unless you have a lot of carbs pre-workout, because peri-workout hypoglycemia is no fun.
 
Hastur said:
It has a 24 hour half life, and with it lowering blood sugar, I'd take it with a meal containing carbs. You can take it at any time, and it will be effective, as it's not the type of supplement you take 30-minutes pre-workout or anything like that. Something I wouldn't advocate anyways unless you have a lot of carbs pre-workout, because peri-workout hypoglycemia is no fun.
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So I usually dont have any carbs till me pre-workout shake around noon which is 25g of glycofuse. +25g during workout and 25g post workout of dextrose. Should I take it during this time? Or a few hours after when I have around 75g of carbs from rice in my next meal?
 
Hastur said:
It has a 24 hour half life, and with it lowering blood sugar, I'd take it with a meal containing carbs. You can take it at any time, and it will be effective, as it's not the type of supplement you take 30-minutes pre-workout or anything like that. Something I wouldn't advocate anyways unless you have a lot of carbs pre-workout, because peri-workout hypoglycemia is no fun.
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Well my only carbs most days come from veggies in my evening meal (except my two refeed days). I guess I'll give the 1/1 dose a try for couple days and see how t works but might potentially just do 2pm
 
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