My experience w/ dhea is it bugged my gyno a lot, just using intermittently. Dermacrine, if you ask me, is more for the TRT crowd that's just looking for balance, not really blasting often. So you'd already have a baseline bloods and then implement the Dermacrine for a month consistently, get bloods, and decide from there (dhea & preg levels naturally fall when TRT is implemented, and eventually often have to be added exogenously, after all).
But not everyone on TRT ever needs to supp with either, or both, dhea and preg. Many get by without.
Anyway, pregnenolone, used orally just here and there makes a very profound impact for me on cycle. All positives except insomnia/inability to sleep long if you overdo it. Hence the using as needed. That might be a better option, as it won't bug the e2. Just google reputable brands, because there are a lot of hit or miss companies.