As far as your list goes, Epi gets better with time. Ashwagandha can also be ran for longer duration. With that in mind, it is good to always to time off to let receptors clear.
I would find a time where stress is lower in your life to take time off from ashwagandha. For example, I teach, so I take time off during the middle to end of the summer, winter break, and spring break.