dito
Member
Stizm FAQ
Invalid Link Removed
What is Stizm?
Stizm is a stimulant/thermogenic/mood enhancer/appetite suppressing supplement. It contains full doses of many potent substances. It is powerful enough to give noticeable effects to those that have an I.V. Of coffee, yet smooth enough to keep you from going insane from stimulation.
What's in it?
Caffeine anhydrous 250mg
Theobromine 200mg
Synephrine HCL 100mg
Octopamine HCL 100mg
Hordenine 100mg
Tyramine HCL 100mg
Phenylethylamine 50mg
What do each of those ingredients do?
Caffeine Anhydrous
Caffeine is a xanthine alkaloid that is a central nervous system stimulant. Caffeine is structurally similar to adenosine, and therefore binds to adenosine receptors in the brain without activating them. The result of this is an increase in epinephrine (Adrenaline) and norepinephrine, which will lead to a stimulation of the sympathetic nervous system which increases blood rate, blood pressure, blood flow to muscle, and also leads to a release of glucose by the liver.
Caffeine is also a competitive inhibitor to cAMP. CAMP is part of the message response to increased epinephrine, so caffeine allows levels of epinephrine to stay elevated longer, which can also intensify and prolong the effects of amphetamines and the like.
Cliff's Notes on Caffeine: Increased thermogenesis, increased energy (adrenaline), and intensification of other epinephrine precursors.
Theobromine
Theobromine is an alkaloid of the methylxanthine family, similar to caffeine. It is the primary xanthine found in chocolate and is one of the reasons for chocolate's ability to improve mood. It is also the reason why chocolate can kill pets since they are not able to metabolize it as well as humans. Even though it is in the same family as caffeine, it's effects are much different. Instead of a short intense rush that can increase anxiety and stress, theobromine is a longer-lasting mood enhancing stimulant.
Synephrine
Synephrine stimulates the beta-3 receptors, which is able to increase the metabolism without increasing heart rate or blood pressure. It is able to increase epinephrine and norepinephrine. It is also an alpha adrenorecptor agonist which increases lipolysis in adipose tissue and decreases appetite.
Octopamine
Octopamine is a trace amine that is derived from tyramine. It stimulates both alpha and beta adrenoreceptors. It is a highly selective beta3 agonist, which means that it should be able to reduce insulin-dependent glucose transport and increase lipolysis. Octopamine is also a selective D1 receptor agonist, meaning that it can increase levels of dopamine. It is also a dopamine reuptake inhibitor, thus increasing dopamine further.
Hordenine
Hordenine plays a big role in stizm. In addition to increasing levels of norepinephrine, it slows digestion and is an MAO inhibitor. By slowing digestion it is able to decrease appetite by keeping you feeling full and satisfied long after a meal. Hordenine's best characteristic is it's ability to inhibit monoamine oxidase enzyme, which is the enzyme that lowers levels of dopamine. Phenylethylamine (a potent mood enhancer that we will discuss shortly) is a dopaminergic supplement, so MAO inhibition is crucial for it to work effectively
Tyramine
Tyramine stimulates norepinephrine and is a reuptake inhibitor or norepinephrine. It also converts to dopamine and decreases it's metabolism by monoamine oxidase aplha.
Phenylethylamine
Phenylethylamine (PEA) is a lot of fun. It is found in chocolate and is the main reason for why chocolate improves your mood. It is commonly referred to as the “love drug” since it is often released when you “fall in love” (whatever that is). PEA works through dopamine and is a potent mood enhancer and anti-depressant. It is quickly broken down by MAO and thus is the need for an MAOI like hordenine.
What effects will you get from Stizm?
Dito put it best when he said that Stizm gives you a stimulating euphoria feeling. With full doses of many potent stimulants (not low doses in hope of synergism) you will be full of energy and ready to go, but with the mood enhancers you should also feel good and avoid the anxiety that many stimulants give. You will also notice a decrease in appetite, which is due to the synephrine and hordenine. Stizm can also aid in weight loss due to it's thermogenic, metabolic rate increasing, and appetite suppressing abilities.
How many caps should I take?
Start off with just one to assess tolerance. Remember, Stizm has a full dose of many potent stimulants, so if you are sensitive to stims or haven't taken any in a while, taking 2 caps on your first dose will be quite an experience.
What's the max dose?
Two caps. From personal experience, three caps is very intense. The euphoria from it is nice, but the stimulation is just too much to be comfortable.
Should I take it on an empty stomach?
Yes.
What happens if I accidentally take too many?
Take some theanine (which can counteract some CNS stimulation) or just buckle down and enjoy the experience.
Stizm is a great addition to any cutting diet, because when you are cutting you are low on energy (due to low calories) and are typically grumpy (due to being low on energy) which can lead to having a tough time staying away from the delicious brownies that you wife/girlfriend/main woman cooked. Stizm works to solve all of these while also increasing weight loss.
That's a lot of synephrine....Is that safe?
Yes. ThermoLife would not put that much in there if it were a lawsuit waiting to happen. Most individuals will be able to handle the amount of synephrine (and other stimulants in Stizm) and will enjoy the energy and appetite suppression. However, some individuals are sensitive to synephrine, thus the recommendation to start with one dose.
Will it be okay to take Stizm at night?
Not unless you plan to stay up all night. Caffeine has a half-life of 7 hours, so it would be best to take Stizm no later than 7-9 hours before you plan to go to sleep.
Invalid Link Removed
What is Stizm?
Stizm is a stimulant/thermogenic/mood enhancer/appetite suppressing supplement. It contains full doses of many potent substances. It is powerful enough to give noticeable effects to those that have an I.V. Of coffee, yet smooth enough to keep you from going insane from stimulation.
What's in it?
Caffeine anhydrous 250mg
Theobromine 200mg
Synephrine HCL 100mg
Octopamine HCL 100mg
Hordenine 100mg
Tyramine HCL 100mg
Phenylethylamine 50mg
What do each of those ingredients do?
Caffeine Anhydrous
Caffeine is a xanthine alkaloid that is a central nervous system stimulant. Caffeine is structurally similar to adenosine, and therefore binds to adenosine receptors in the brain without activating them. The result of this is an increase in epinephrine (Adrenaline) and norepinephrine, which will lead to a stimulation of the sympathetic nervous system which increases blood rate, blood pressure, blood flow to muscle, and also leads to a release of glucose by the liver.
Caffeine is also a competitive inhibitor to cAMP. CAMP is part of the message response to increased epinephrine, so caffeine allows levels of epinephrine to stay elevated longer, which can also intensify and prolong the effects of amphetamines and the like.
Cliff's Notes on Caffeine: Increased thermogenesis, increased energy (adrenaline), and intensification of other epinephrine precursors.
Theobromine
Theobromine is an alkaloid of the methylxanthine family, similar to caffeine. It is the primary xanthine found in chocolate and is one of the reasons for chocolate's ability to improve mood. It is also the reason why chocolate can kill pets since they are not able to metabolize it as well as humans. Even though it is in the same family as caffeine, it's effects are much different. Instead of a short intense rush that can increase anxiety and stress, theobromine is a longer-lasting mood enhancing stimulant.
Synephrine
Synephrine stimulates the beta-3 receptors, which is able to increase the metabolism without increasing heart rate or blood pressure. It is able to increase epinephrine and norepinephrine. It is also an alpha adrenorecptor agonist which increases lipolysis in adipose tissue and decreases appetite.
Octopamine
Octopamine is a trace amine that is derived from tyramine. It stimulates both alpha and beta adrenoreceptors. It is a highly selective beta3 agonist, which means that it should be able to reduce insulin-dependent glucose transport and increase lipolysis. Octopamine is also a selective D1 receptor agonist, meaning that it can increase levels of dopamine. It is also a dopamine reuptake inhibitor, thus increasing dopamine further.
Hordenine
Hordenine plays a big role in stizm. In addition to increasing levels of norepinephrine, it slows digestion and is an MAO inhibitor. By slowing digestion it is able to decrease appetite by keeping you feeling full and satisfied long after a meal. Hordenine's best characteristic is it's ability to inhibit monoamine oxidase enzyme, which is the enzyme that lowers levels of dopamine. Phenylethylamine (a potent mood enhancer that we will discuss shortly) is a dopaminergic supplement, so MAO inhibition is crucial for it to work effectively
Tyramine
Tyramine stimulates norepinephrine and is a reuptake inhibitor or norepinephrine. It also converts to dopamine and decreases it's metabolism by monoamine oxidase aplha.
Phenylethylamine
Phenylethylamine (PEA) is a lot of fun. It is found in chocolate and is the main reason for why chocolate improves your mood. It is commonly referred to as the “love drug” since it is often released when you “fall in love” (whatever that is). PEA works through dopamine and is a potent mood enhancer and anti-depressant. It is quickly broken down by MAO and thus is the need for an MAOI like hordenine.
What effects will you get from Stizm?
Dito put it best when he said that Stizm gives you a stimulating euphoria feeling. With full doses of many potent stimulants (not low doses in hope of synergism) you will be full of energy and ready to go, but with the mood enhancers you should also feel good and avoid the anxiety that many stimulants give. You will also notice a decrease in appetite, which is due to the synephrine and hordenine. Stizm can also aid in weight loss due to it's thermogenic, metabolic rate increasing, and appetite suppressing abilities.
How many caps should I take?
Start off with just one to assess tolerance. Remember, Stizm has a full dose of many potent stimulants, so if you are sensitive to stims or haven't taken any in a while, taking 2 caps on your first dose will be quite an experience.
What's the max dose?
Two caps. From personal experience, three caps is very intense. The euphoria from it is nice, but the stimulation is just too much to be comfortable.
Should I take it on an empty stomach?
Yes.
What happens if I accidentally take too many?
Take some theanine (which can counteract some CNS stimulation) or just buckle down and enjoy the experience.
Stizm is a great addition to any cutting diet, because when you are cutting you are low on energy (due to low calories) and are typically grumpy (due to being low on energy) which can lead to having a tough time staying away from the delicious brownies that you wife/girlfriend/main woman cooked. Stizm works to solve all of these while also increasing weight loss.
That's a lot of synephrine....Is that safe?
Yes. ThermoLife would not put that much in there if it were a lawsuit waiting to happen. Most individuals will be able to handle the amount of synephrine (and other stimulants in Stizm) and will enjoy the energy and appetite suppression. However, some individuals are sensitive to synephrine, thus the recommendation to start with one dose.
Will it be okay to take Stizm at night?
Not unless you plan to stay up all night. Caffeine has a half-life of 7 hours, so it would be best to take Stizm no later than 7-9 hours before you plan to go to sleep.
Last edited by a moderator: