So how bad is Ostarine for you REALLY?

klbsa

klbsa

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The bro science says everything from mild on the body to it will rot your liver.

Im asking because I am being plagued by shoulder pain, and as little as 10 mg a day of ostarine makes it all but go away in a matter of 1-2 days. But a week after I stop taking it, shoulder pain again.

what If I just stayed on the stuff long term? I mean for let’s say 6 months? At a mild 10mg a day, what kind of damage would I be doing?
 

Uncle_E

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Have you gone to a doctor? I’d try that before running some junk sarm for 6 months.

That being said, I had a slight tear in a wrist ligament and used Anavar to help the healing process. I considered Ostarnine, but went with Anavar. After it was diagnosed with an MRI, it was small enough that I didn’t want to gamble on surgery making it worse. I immobilized the joint for some time, took lots of Cissus XT, rubbed Helios on it daily for inflammation, then took the Anavar for 4 weeks or so.

A bit of bro-science and luck, and everything is working properly again. I would not have entertained that approach for 6 months though.
 
klbsa

klbsa

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Have you gone to a doctor? I’d try that before running some junk sarm for 6 months.

That being said, I had a slight tear in a wrist ligament and used Anavar to help the healing process. I considered Ostarnine, but went with Anavar. After it was diagnosed with an MRI, it was small enough that I didn’t want to gamble on surgery making it worse. I immobilized the joint for some time, took lots of Cissus XT, rubbed Helios on it daily for inflammation, then took the Anavar for 4 weeks or so.

A bit of bro-science and luck, and everything is working properly again. I would not have entertained that approach for 6 months though.
I do have good amounts of anavar….. How much did you take a day?
 

Mikereyn513

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What about bpc? Just a thought..anavar with a ton of fish oil sounds good tho
 
Smont

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Ostarine, anavar, bpc, it just sounds like everybody's throwing out random names of anabolics and peptides without even knowing what the actual injury is. Shoulder pain doesn't tell us anything about the injury and taking steroids and peptides are not cures for pain.

You need to find out what's causing the pain, and out of all the things mentioned so far bpc is most likely going to be the best option
 
Renew1

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Like @Smont , I recommend avoiding Ostarine.
Anavar is great, and one of my favorites... But I wouldn't use Any steroids continuously.
 
Smont

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Have you gone to the doctor and had your shoulder x-rayed or gotten an MRI? That's something you should probably figure out before you start playing guessing games. Would that being said I've used BBC 157 several times on my left shoulder, I have a partial tear in my rotator cuff and when it flares up and gets really bad the BBC makes it better, somewhat temporarily but it seems like the more times I do it the longer it feels better it's been quite a while since I've used bpc and I've had no issues for a long time and I've been flat benching very heavy lately with no pain at all
 
BCseacow83

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If the pain comes back as soon as you go off the ostarine it is NOT healing anything and is simply masking the pain. So at some point you will have to come back off and boom pain is back. The pain could actually get worse as all you did was mask the pain potentially allowing you to further injure your shoulder.

No one knows how long-term ostarine use effects the human body as it has NOT been studied in such manner, at least not yet.

So we have a non-traditional potentially anti-inflammatory experimental drug with liver, lipid, and HPTA suppressing effects and for some estrogen sides assuming you are getting real ostarine to begin with. All these things, IMO, make it a poor choice for long-term pain management.
 

Uncle_E

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I do have good amounts of anavar….. How much did you take a day?
I just went back on my notes and it was a lot more than Anavar. Here’s what I took in addition to TRT + HCG:
Cissus XT
Fish Oil
CJC + DAC
Ipamorelin
BPC-157
TB500
Anavar at 50mg/day

This was all after diagnosis though. The wrist joint is so small, it seemed like there was fair risk the the repair surgery could cause more problems than the injury.
 
mikeymike85

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Osta blows. If you are comparing Var v Osta, Var x100000- not even within the same stratosphere. I've run Var only cycles (I know many people say not to)-- but at very high doses, for 10 weeks-- changes the physique.
 
mTOR25

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It seems to be extremely weak and studies and anecdotal reports are showing liver toxicity on a level that makes it hard to justify for whatever little muscle sparring or performance boosting effects it might have!
 

beefyfan

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Have you gone to the doctor and had your shoulder x-rayed or gotten an MRI? That's something you should probably figure out before you start playing guessing games. Would that being said I've used BBC 157 several times on my left shoulder, I have a partial tear in my rotator cuff and when it flares up and gets really bad the BBC makes it better, somewhat temporarily but it seems like the more times I do it the longer it feels better it's been quite a while since I've used bpc and I've had no issues for a long time and I've been flat benching very heavy lately with no pain at all
What the **** does this have to do with your shoulder? 😁
 
Smont

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so you lovin that BBC??? :p:LOL:
See, when I see BBC I typically think British broadcasting company. The rest of you guys are thinking about that last cuck porn you watched 😂😆😂, except for beefyfan, he's thinking about his last grinder date 🍆lol.

Seriously tho, i completely missed that, if he didn't point that out I would have never noticed I did that, one time my phone auto corrected tren to tranny, that one didn't go over well either😬
 
UncleSarm

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It seems to be extremely weak and studies and anecdotal reports are showing liver toxicity on a level that makes it hard to justify for whatever little muscle sparring or performance boosting effects it might have!
Any links to the studies reporting liver toxicity?
 
UncleSarm

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Google is pretty simple to use....
.
"Ostarine is possibly unsafe. It might cause liver damage and other serious side effects such as heart attack."
"possibly" unsafe, "might" cause liver damage ... and no links to any actual evidence

Liver injury associated with the use of selective androgen receptor modulators and post-cycle therapy: Two case reports and literature review
"two cases of liver injury in young men who used ligandrol and/or ostarine for a few weeks followed by the use of substances for PCT."
"Acute liver injury occurred in both cases after stopping SARMs while on PCT"
"The off target effects of SARMs were likely idiosyncratic, but our report highlights the yet unrecognized effects of other toxic substances used for PCT"

Drug-Induced Liver Injury From Enobosarm (Ostarine), a Selective Androgen Receptor Modulator
"a case of significant cholestatic liver injury associated with a SARM, ostarine (enobosarm), similar to that associated with anabolic steroids"

Selective Androgen Receptor Modulators (SARMs)-Induced Liver Injury: A Case Report and Review of Literature
"a 22-year-old, previously healthy male, who presented with a two-week history of worsening jaundice, nausea, fatigue, pruritus, dark urine, and light stools. He reported taking the SARM, RAD-140, for 16 weeks"

Selective Androgen Receptor Modulator Induced Hepatotoxicity
"patient started taking a SARM supplement approximately four weeks prior for bodybuilding"

Non-steroidal anti-inflammatory drugs: What is the actual risk of liver damage?
"roughly 10% of total drug-induced hepatotoxicity is NSAIDs related"
"chronic alcohol abuse during treatment with paracetamol was associated with an increase in liver injury"

So this is what I found using google:
- 3 cases of liver toxicity related to Ostarine/Enobosarm use, 2 of which were likely caused by PCT drugs
- 1 case of liver toxicity related to RAD-140 use
- 1 case of liver toxicity related to a non-identified SARM
- 0.29/100 000 to 9/100 000 cases of incidence of liver disease induced by NSAIDs

The scientific literature that I found does not support the fact that SARMs are particularly liver toxic. Any drug or medication carries a potential health risk due to underlying health issues, or drug-to-drug interaction, alcohol, taking excessive amounts, or taking it over a prolonged duration. Also, even assuming that these numbers were high, none of the reported cases resulted in death or permanent liver damage.

I have done multiple cycles of Osta with my first one logged here along with full bloods: First Osta cycle. I have also cruised on 10mg of Osta for two years, taking bloods every 3-6 months. Yeah, I'm not going to argue if that was a dumb idea or not.
So my question for links to recent scientific studies that I may have missed was based on personal interest.
 

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