SNS Inhibit E Half Life

Interested in buying this supplement however no where on the label states half life? Any ideas, thank you

Do many supplements state the half life on the label? Not in my experience. You’d need full pharmacokinetic research into each ingredient and their individual compounds to have that. And since some herbal ingredients can have dozens of compounds identified in them, it wouldn’t be realistic.

Essentially you’d need to look up each individual ingredient. And even then, good luck, since the compounds within ingredients will have a varying half life.

For instance, pulling Olive Leaf Extract from the Inhibit E label: it’s extracted for Oleuropein, which has some half life (which probably varies based on fasted or fed state when consuming), but the extract might also contain tyrosol, apigenin, kaempferol, luteolin etc and those will all have a different half life.

Basically, half life is interesting when we’re looking at single ingredients, but when you have a multi-ingredient product, there’s going to be so much variability. Also there’s just individual variability in how people process ingredients. If you look into pharmacokinetic research with prescription drugs, there’s quite a bit of variability in metabolism.

Because of this, if you’re trying to be most optimal, I’d evenly spread out the dosing throughout the day and be consistent day to day. If doing 3 caps, then maybe like 8am, 2pm, 8pm… if doing 2 caps, maybe 8am and 8pm… you get the picture. It’s not like caffeine which you feels acutely, so I’d just be consistent daily.
 
Interested in buying this supplement however no where on the label states half life? Any ideas, thank you

Aaron explained it well in post #2

also im curious too which country are you in where they state half lifes on a label ?
i have seen them only when it comes to sarms .. should be included in ph/ds too imo for beginners

but not for natural stuff doesn't make sense imo and very hard to determine and more importantly "why" lol
 
I think you might be overthinking if your curious about half life but if your curious
about what the effects were here's a straight up honest review.
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Interested in buying this supplement however no where on the label states half life? Any ideas, thank you

Aaron's post below explained this perfectly.

The only thing I can really add is that it would actually literally be illegal to make a half life claim on a multi-ingredient product label.

The suggested use on the bottle backs up his statements of spacing your dosage out:
As a dietary supplement, take three (3) capsules per day. For best results, dosage can be spaced out evenly throughout the day, with or without meals.

Do many supplements state the half life on the label? Not in my experience. You’d need full pharmacokinetic research into each ingredient and their individual compounds to have that. And since some herbal ingredients can have dozens of compounds identified in them, it wouldn’t be realistic.

Essentially you’d need to look up each individual ingredient. And even then, good luck, since the compounds within ingredients will have a varying half life.

For instance, pulling Olive Leaf Extract from the Inhibit E label: it’s extracted for Oleuropein, which has some half life (which probably varies based on fasted or fed state when consuming), but the extract might also contain tyrosol, apigenin, kaempferol, luteolin etc and those will all have a different half life.

Basically, half life is interesting when we’re looking at single ingredients, but when you have a multi-ingredient product, there’s going to be so much variability. Also there’s just individual variability in how people process ingredients. If you look into pharmacokinetic research with prescription drugs, there’s quite a bit of variability in metabolism.

Because of this, if you’re trying to be most optimal, I’d evenly spread out the dosing throughout the day and be consistent day to day. If doing 3 caps, then maybe like 8am, 2pm, 8pm… if doing 2 caps, maybe 8am and 8pm… you get the picture. It’s not like caffeine which you feels acutely, so I’d just be consistent daily.

Great post and attention to detail. Thank you for so thoroughly explaining.
 
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