Sildenaphil & DMAA a Deadly Combinations or the Perfect Combo?

JamesWD

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I have been reading a lot of studies on the use of DMAA in preworkouts. From what I read, it functions primarily as a vasoconstrictant and redirects blood flow to the brain. Although DMAA acts like an amphetamine such as adderall, and even shares a similar molecular structure as adderall, the dosage for DMAA is much higher to get the same results as aderall. The negative side effects of DMAA are high blood pressure, possibility of stroke or heart attack, and reduced oxygen delivery to muscles among others.

Sildenaphil on the other hand works almost completely opposite as DMAA. It functions primarily as a vasorelaxant. It dilates epicardial coronary arteries (reducing blood pressure), improves endothelial dysfunction and enhances oxygen delivery to the muscles.

Since both of these molecules function quit differently, I am wondering if anyone has had any experience taking the two before a workout. I personally think it would be a very bad idea, but I don't know. Maybe people take sildenaphil to offset the high blood pressure caused by DMAA. Has anyone every tried this? What was your experience?
 

Jeremyk1

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Where did you get your info on DMAA? The FDA?

It does not primarily act as a vasoconstrictor. It can undoubtedly cause transient increases in heart rate and blood pressure, but that isn’t its mechanism of action.
 
JamesWD

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DMAA functions like epinephrine, which constricts your blood vessels and increases blood pressure/heart rate, such as during flight or fight response. Amphetamines like Aderrall function very similar. They both act on the sympathetic nervous system.
 
irone93

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I take this combo every time I work out. It is the ****. Great pump and great focus, don’t notice a downside
 

Jeremyk1

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DMAA functions like epinephrine, which constricts your blood vessels and increases blood pressure/heart rate, such as during flight or fight response. Amphetamines like Aderrall function very similar. They both act on the sympathetic nervous system.
I know what DMAA does and how it works. You, however, seem awfully confused. Yes, it can transiently increase heart rate and blood pressure. I done said that already. You had said that that is it’s primary function or whatever. Which is wrong.
 
irone93

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This is actually my go to pre workout stack. I feel amazing on it and the pumps are great
 
Old Witch

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Sildenaphil & DMAA a Deadly Combinations or the Perfect Combo?

Usually tadalafil is preferable as a blood pressure lowering device in hardcore bodybuilding and powerlifting circles. Sildenafil is a preworkout or prosexual device. Yes it is often combined in dosage with dmaa. I have seen guys taking Assassin Undefeated to actually wash down some cialis or directly after pinning their (usually way too strong) PWO steroid mixture.

However in those same circles amphetamine itself is preferred to preworkout, and in those users, preworkout or pump powder is replaced by stim free amino acid powders citrulline etc. as nitrates in pump powder will negatively interact with the tadalafil or sildenafil in a possibly lethal way.

So to recap, Hardcore preworkout or precomp equals amphetamine and aminos or DMAA PWO, with cialis and/or viagra and fast acting steroids.
 
Old Witch

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A good dmaa preworkout should have some nitrogen increasing effects of its own and vinpocetine, huperazine etc to relax blood flow to the brain.
 
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