RPM on Cycle??

If RPM is truly a SARM type product. Then don't you think it would be very beneficial on cycle due to the fact that it could block the androgen negative feedback loop in the hypothalamus?

Isn't that what a SARM is aimed to accomplish?
 
Giantz11 said:
If RPM is truly a SARM type product. Then don't you think it would be very beneficial on cycle due to the fact that it could block the androgen negative feedback loop in the hypothalamus?

Isn't that what a SARM is aimed to accomplish?
Click to expand...

That's EXACTLY what I (and my research monkey :D) are about to find out! I have some 1AD and 4AD that my monkey will be running starting next week with some RPM and possibly ATD before bed also.
 
Giantz11 said:
If RPM is truly a SARM type product. Then don't you think it would be very beneficial on cycle due to the fact that it could block the androgen negative feedback loop in the hypothalamus?

Isn't that what a SARM is aimed to accomplish?
Click to expand...

Absolutely!! RPM stacks quite well with any AAS- especially in the strength/hardness/vascularity department- in my experience it is actually more effective (and cheaper) than certain other "un-natural" physique hardeners out there- with less sides as well.

As far as competition w/ steroid molecules for similar receptors, this is one of the things I took into account when formulating RPM- BUT I need access to frequent blood tests to confirm this, and I don't at the moment :(

Theoretically, it is a possibility, b/c icariin and steroid molecules seem to target the same areas (glucocorticoid and androgen rec.)- but the icariin would have to "crowd out" the steroid molecules in this aspect to stop the inhibition, and I am not sure which one is a better fit for the receptors- that is usually the compound that will "win out" so to speak.....
 
thewilman said:
That's EXACTLY what I (and my research monkey :D) are about to find out! I have some 1AD and 4AD that my monkey will be running starting next week with some RPM and possibly ATD before bed also.
Click to expand...

Great stuff, let me know what your feedback is.
 
rms80 said:
Absolutely!! RPM stacks quite well with any anabolic steroids- especially in the strength/hardness/vascularity department- in my experience it is actually more effective (and cheaper) than certain other "un-natural" physique hardeners out there- with less sides as well.

As far as competition w/ steroid molecules for similar receptors, this is one of the things I took into account when formulating RPM- BUT I need access to frequent blood tests to confirm this, and I don't at the moment :(

Theoretically, it is a possibility, b/c icariin and steroid molecules seem to target the same areas (glucocorticoid and androgen rec.)- but the icariin would have to "crowd out" the steroid molecules in this aspect to stop the inhibition, and I am not sure which one is a better fit for the receptors- that is usually the compound that will "win out" so to speak.....
Click to expand...


Excellent, I'm sure some of "us" would be willing to try this out and report out findings.

Also what the hell is it that makes you so aggressive when take Pre WO? I mean hell, 600mg of Test/week doesn't even do that.
 
If I had to guess, and I'm just talking out my butt here, I'd say that Icariin has a strong affinity for the AR in the brain. I'm hooked on this stuff purely for the mood and energy boost...feels like a nice dose of test in some ways.

I kind of doubt that Icariin would out compete actual testosterone at the receptor site..but stranger things have happened in the endocrinology-herbal fields.

At the very least, Icariin makes a great phyto version of test.
 
bioman said:
If I had to guess, and I'm just talking out my butt here, I'd say that Icariin has a strong affinity for the AR in the brain. I'm hooked on this stuff purely for the mood and energy boost...feels like a nice dose of test in some ways.

I kind of doubt that Icariin would out compete actual testosterone at the receptor site..but stranger things have happened in the endocrinology-herbal fields.

At the very least, Icariin makes a great phyto version of test.
Click to expand...

Interesting. Both the thoughts, and your butt's vocabulary.
 
rms just evoked Bruce... uh-oh

Tried callin you earlier D..... you must have been RPMing (new word to refer to any random act of physical action that one does) Similar in use to Smurfing.
 
I had what I'm pretty sure was an interaction issue with RPM and Atarax (hydroxyzine) a really, really stong antihistamine. I talked to Dr.D about it, and he said that the Atarax also causes vessel dilation. I had one of the worst headaches of my entire life for 4 days or so. :sick:

So maybe be careful taking RPM with antihistamines (diphenhyramine, Nyquil, maybe even Claritin, etc. ).
 
Eww. Those multi day headaches are hell to get rid of. Was icing my neck last night to ward one off.
 
supersoldier said:
I had what I'm pretty sure was an interaction issue with RPM and Atarax (hydroxyzine) a really, really stong antihistamine. I talked to Dr.D about it, and he said that the Atarax also causes vessel dilation. I had one of the worst headaches of my entire life for 4 days or so. :sick:

So maybe be careful taking RPM with antihistamines (diphenhyramine, Nyquil, maybe even Claritin, etc. ).
Click to expand...

That will go in the FAQs- good looking out!!

RPM does not interact with Zyrtek, b/c that is what my wife takes, and she has not had issues...
 
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