Rebound after succesful Gyno Reversal

[DunkoroChitlu]

When ralox binds with the ER in breast tissue, it acts as an antagonist. Meaning it bonds with but has little to no interaction with the er.
Taking this for months will in a sense, de sensitize the er.
Then when you stop the drug, that ER is now open and for your estrogen to bind with.
So you’ve went say 1,2,3 months with no interaction, the estrogen comes along and bonds with, and interacts it’s gonna be like taking that first sip of your favorite beverage after 3 long months…and begin doing what estrogen does.
And that’s not even taking into account how your hormones look at baseline.
All natty, never touching anything.
Gyno is a mix of multiple hormonal imbalances going on that start by touching anything that disrupts your hptga, from test, estrogen, to hgh, prolactin, etc.
Maybe this thread will help.
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Thanks for your detailed answer. It completely makes sense what you're mentioning.

However if you check my blood reports, my estro is relatively low (about 14 out of the 39 which is on the high side of the range). So not sure how gyno grew with such low estro in blood? Maybe it had to do with the sensitivity when removing Ralox, that every estrogen particle (even if low quantity) would bind to the tissue.
Or that or my high testosterone levels (near high end of the range) was aromatizing.
So it makes sense to run an IA at the end of the Ralox cycle and continue it after the Ralox cycle as well to avoid high test circulation.
It's a bit confusing.

 

[DunkoroChitlu]

I don't see any benefits to 15mg of ralox in the shrinking process. Maybe 15 as a prevention measure on a cycle. I also don't see any need to taper off so gradually. Most successful gyno shrinking I did with 12.5mg exemestane daily and 100mg or ralox for weeks 1 and 2. Weeks 3 and 4 I did 12.5 exem eod and 50mg ralox daily and the following 4 weeks I did just ralox 50 mg a day.

Over the past 3 years or so I had to run a protocol 3 or 4 timesaving that was the most aggressive one and ot worked the best. It's been over 6 months and it's still not coming back. It will eventually tho. It always comes back to some degree

Whats the purpose of running more exemestane at the beginning of the ralox cycle than the end?

When you stop having ralox, estrogen receptor is much more sensitive to estrogen, so it would make sense to have low levels of estro towards the end of the ralox cycle, not the beginning to avoid a rebound. As far as my understanding goes.

Because from my personal experience, as you can see, I was just running ralox without any IA because my estrogen levels were in good numbers (22) right in the middle of the range. After quitting the 15mg dose, it nipple started to itch during a few days and it grew back (maybe even worse). So I'm a bit confused with what you're mentioning