1-Andro can cause lethargy if taken solo. Most people run a Test Base, using either 4-AD, Epiandrosterone, or Dermacrine. These would also help libido, but if it's still lacking, any plant or root known for libido, can be taken too.
1-Andro is a DHT derivative, so if you want to be extra careful, you could run naturals known to protect the prostate and hairline: Stinging Nettle, Saw Palmetto, Pumpkin Seed Oil, Pygeum, etc.... Most OTC 'On Cycle Support' products have some of those.
The 6,7 DHB is a Cytochome P 450 inhibitor. There is some mild liver stress when this is added to a PH cycle. According to the West Texas A&M study, it is temporary, but if you want, you could also use NAC, Milk Thistle, L-Glutathione, etc... Again, On Cycle supps usually have some of this. I have a post in the Anabolics section asking if TUDCA would be wise, of if it's over-kill - but no answers yet.
Bulk Taurine can handle Back Pump, but I never experienced any.
I'm coming across a lot of opinions that running BOTH 4-AD *and* EpiAndro as a Test Base... is pretty nice. I may be adding EpiA to a 4-AD/19-Nor cycle I have coming up in a few months.