Question about sides from topical

[1newbie]

Been reading that home made topicals have about 30% bioavailability versus 10% if taken orally, so 1/3 the amount should give the same gains. If you are taking 1/3 the amount, will the sides be lessened or the same because your body is still getting the same net amount. Are some PH too large a molecule to pass TD? Seems that should be way easier on the liver although the compounds I'm considering (hdrol, 11-sterone) aren't methylated.

 

[grngoloco]

Hdrol is methylated,,, not sure about homemade transdermals,, but I do know androgel only has a 10% absorption rate,, be surprised if homemade td's are superior to pharmaceutical ...

 

[1newbie]

Was going to use topical solution by PP, hdrol always makes me feel like crap.

 

[ManBeast]

not everything can make it through a transdermal.

 

[grngoloco]

Wouldn't you just use pure DMSO?