Think to me at least it's completely irrelevant ( regarding the benefits of blend vs isolate ), I doubt many are eating a single source protein and it's taking time to break down and be utilized by which time I am sure you/anyone would have eaten a meal and in this life style loaded with protein.
I know I drink my shakes with a meal, so isolate/blend/casein I highly doubt would ever make a difference. Keep in mind world wide the population at large has lactose issues around 65% globally and in some populations ( Asians ) that can be as high as 90%.
Edit: The few Isolates I do have I am mixing into Fairlife whole milk/2% milk just FYI and or whole fat strained yogurt ( Fa-ge Yogurt ) haha I just think it's not worth looking at in isolation when people do not consist/eat in such a way at least pertaining to the debate is isolate vs blend or vs casein even more so when such a large amount of individuals have lactose issues regarding protein powder and the fact that you do not at all need it - it's powdered food.
That snickerdoodle doe...

I wish they would have made that peppermint bark limited edition flavor a normal flavor option... like wtf