I don't know about growth plate closure but, Orastan is supposedly very close to real stanazol(winstrol) in chemical makeup.
But steroids taken before your body has fully developed 22-26 yrs, can stunt bone growth.
But on the subject of Orastan-e, I tried it. I was very disappointed with it. First couple of weeks a felt a little something, but not much else.
And you know the shitty thing about that was? I can get real stanazol for less that half the price of that garbage.
Ain't that a bitch?