Mike Arnold
Board Sponsor
ProSynthesis-17 More Effective than Standard EAA Products
As we all know, protein quantity is a crucial factor in the regulation muscle growth. We must have enough amino acids present if we hope to optimize the growth process. This is why all bodybuilders and strength athletes consume large amounts of protein foods, protein powders, etc. EAA products are also part of this equation and are great for stimulating protein synthesis, but they just don't contain very many building blocks (i.e., amino acids). This is why we never depend on them to replace a protein meal. Up until now, they have simply been additions to our existing meal plan.
This is one of the big reasons ProSynthesis-17 was created. I wanted a product that was able to stand alone; a product that not only stimulated protein synthesis, but which also provided all the building blocks necessary for taking full advantage of its powerful muscle building signal.
Well, it appears that ProSyntheis-17 is even more powerful than it appears. In addition to providing a massive amount of building blocks (e.g., amino acids), it also provides a greater anabolic & anticatabolic effect than today's EAA products. According to the research below (scroll to the bottom), high-dose EAA intake (25 grams; the EXACT amount in ProSynthesis-17) not only stimulates protein synthesis to a greater degree than moderate-dose EAA intake (10-14 grams), but its also more effective at halting protein breakdown!
In short, ProSynthesis-17 stimulates MORE protein synthesis, provides a GREATER anticatabolic effect, AND provides a larger number of building blocks!
Translation: More muscle growth!
Oh yeah, don't forget that ProSynthesis-17 also provides a significant dose of additional, growth signaling CEAAs & growth factors.
If you want to learn more about the superior nature of ProSyntheis-17, please view any of the multiple threads posted here in the general supplement forum.
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Note: Ignore the "other ingredient's" section, as my graphic designer utilized generic terms while waiting to be told what the correct "other ingredients" are.
Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study
Abstract
Background & aims: Consuming 0.10-0.14 g essential amino acids (EAA)/kg/dose (0.25-0.30 g protein/kg/dose) maximally stimulates muscle protein synthesis (MPS) during energy balance. Whether consuming EAA beyond that amount enhances MPS and whole-body anabolism following energy deficit is unknown. The aims of this study were to determine the effects of standard and high EAA ingestion on mixed MPS and whole-body protein turnover following energy deficit.
Design: Nineteen males (mean ± SD; 23 ± 5 y; 25.4 ± 2.7 kg/m2) completed a randomized, double-blind crossover study consisting of two, 5-d energy deficits (-30 ± 4% of total energy requirements), separated by 14-d. Following each energy deficit, mixed MPS and whole-body protein synthesis (PS), breakdown (PB), and net balance (NET) were determined at rest and post-resistance exercise (RE) using primed, constant L-[2H5]-phenylalanine and L-[2H2]-tyrosine infusions. Beverages providing standard (0.1 g/kg, 7.87 ± 0.87 g) or high (0.3 g/kg, 23.5 ± 2.54 g) EAA were consumed post-RE. Circulating EAA were measured.
Results: Postabsorptive mixed MPS (%/h) at rest was not different (P = 0.67) between treatments. Independent of EAA, postprandial mixed MPS at rest (standard EAA, 0.055 ± 0.01; high EAA, 0.061 ± 0.02) and post-RE (standard EAA, 0.055 ± 0.01; high EAA, 0.065 ± 0.02) were greater than postabsorptive mixed MPS at rest (P = 0.02 and P = 0.01, respectively). Change in (Δ postabsorptive) whole-body (g/180 min) PS and PB was greater for high than standard EAA [mean treatment difference (95% CI), 3.4 (2.3, 4.4); P = 0.001 and -15.6 (-17.8, -13.5); P = 0.001, respectively]. NET was more positive for high than standard EAA [19.0 (17.3, 20.7); P = 0.001]. EAA concentrations were greater in high than standard EAA (P = 0.001).
