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Ostarine Questions

I'm one of the lucky ones that runs 25-30 mg and notices no sides except a slightly lowered sex drive. I love the stuff but to each their own I wouldn't like it if I got half the sides some of you experience. What Osta is everyone using? I find it very weird users went from noticing very few sides to all of the sudden noticing a plethora of them.
 
I'm one of the lucky ones that runs 25-30 mg and notices no sides except a slightly lowered sex drive. I love the stuff but to each their own I wouldn't like it if I got half the sides some of you experience. What Osta is everyone using? I find it very weird users went from noticing very few sides to all of the sudden noticing a plethora of them.

BSL PCT IV. 2 caps a day split AM/PM to keep levels steady. The trib in it makes me pretty horny as all get out I must say.
 
Any crazy sides like some of the aforementioned ones?

Nah. About half way done with the first bottle. Can't say that I've really noticed much apart from feeling like it's mating time 24/7 likely from the trib. It's 24 mg of ostarine per two caps jus FYI. It's likely there's some suppression going on but I would need bloods to know for sure. Good thing about ostarine however is that there's not much negative health marker sides of note, so toxicity honestly does not feel like it should be much of a concern. Prostate is fine as well, so the stream is a flowing fine.
 
I posted blood work earlier.
It was good until week 3-4,(better libido too) then suppression signs came and no more gains.
 
I posted blood work earlier.
It was good until week 3-4,(better libido too) then suppression signs came and no more gains.

I don't even notice much in the gains department. LoL. Will see how it goes after the full 8 weeks. Right now though, I will probably not bother with ostarine in the future.
 
Nah. About half way done with the first bottle. Can't say that I've really noticed much apart from feeling like it's mating time 24/7 likely from the trib. It's 24 mg of ostarine per two caps jus FYI. It's likely there's some suppression going on but I would need bloods to know for sure. Good thing about ostarine however is that there's not much negative health marker sides of note, so toxicity honestly does not feel like it should be much of a concern. Prostate is fine as well, so the stream is a flowing fine.

So two weeks you've been on? I run it 8 weeks it usually picks up week 3 and continues to get better ime. Maybe I just respond really well to it. I used osta rx for all my runs.
 
I say it cause he is starting back up gym in a few weeks so in my mind it would be better to have a possible high estro issue sorted and test levels recovered by then instead of going into PCT shortly after returning to the gym. Then after working out for a while he will be good to cycle again.
he's not using it as a cycle though. Simply to prevent muscle wasting. There's no gains to lose during pct or anything and at a small dose it should be a very quick recovery even with OTC pct.
 
So two weeks you've been on? I run it 8 weeks it usually picks up week 3 and continues to get better ime. Maybe I just respond really well to it. I used osta rx for all my runs.

That is the plan :) Thus I have no finalized opinions on it yet. We're likely using the same ostarine source as well since IML and BSL may as well be the same company.

I meant the full 8 weeks btw. Stupid type. I have corrected my post :P
 
I'm just done with this thread lol
 
That is the plan :) Thus I have no finalized opinions on it yet. We're likely using the same ostarine source as well since IML and BSL may as well be the same company.

I meant the full 8 weeks btw. Stupid type. I have corrected my post :P

I'm curious why are you running an AI pctiv, if the slight increase in estrogen is supposed to be a good thing?
Should I be running an AI as well?
 
I'm curious why are you running an AI pctiv, if the slight increase in estrogen is supposed to be a good thing?
Should I be running an AI as well?

It's not much of an AI (arimistane) in practice. Good cortisol blunter though. So it's not going to do much in terms of negating a lot of the aromatase enzyme.

I've taken 75 mg of arimistane ED for a little over 12 weeks, didn't really notice low estrogen sides until around the 10th week (and even then, it wasn't all that bad, slight moodiness and a minor but noticeable drop in libido) so tbh, it's not going to affect the ostarine run here.

Basically taking the PCT IV product for the ostarine content.
 
For me, purely lean gains.

Lean gains then I would run a low dose of topical form. If you wanted the tendon/bone healing benefits I would forgo the use of an AI because the slight increase in estrogen will be beneficial in that case.
 
he's not using it as a cycle though. Simply to prevent muscle wasting. There's no gains to lose during pct or anything and at a small dose it should be a very quick recovery even with OTC pct.

Alright man not gonna go further with this with you. But i will say there is a difference with preventing muscle wasting for a person in a diseased state for holding onto essential muscle vs a meathead who isnt providing resistance stimuli wanting to keep his muscles.

The end.
 
Hypothetical here, but since Ostarine supposedly has anti-estrogen effects, wouldn't it make more sense to taper the cycle at the end? I've seen some AAS users taking extremely low dose Ostarine as a PCT. Wouldn't it make more sense that a cycle of this stuff should look more like a pyramid then going cold turkey?
 
Osta seemed to slowly get better, for me. I felt like I was fuller after a couple weeks. I used it on a cut (at the end of a long cut) and I didn't lose any strength while on it and even made small progress. It was a slow builder, though.



20mg @ 8 weeks.

I would use it again for strength/muscle retention deep into a cut. It was noticeable, not drastic. A good tool for that task.
 
Extrapolating that theory based on current studies on the compound is pretty far fetched. IMO.
how am I extrapolating? IIRC the studies looked at exactly this: blunting muscle wasting. And when they saw positive results, that would confirm.
 
how am I extrapolating? IIRC the studies looked at exactly this: blunting muscle wasting. And when they saw positive results, that would confirm.

Well you are using data based on people with a disease which leads to loss of LBM and using the findings on this to theorize that these results will be seen in healthy atheletic populations. that is how you are extrapolating. Don't take me as being a smart arse with you, cause that isn't my intention at all.
 
Well you are using data based on people with a disease which leads to loss of LBM and using the findings on this to theorize that these results will be seen in healthy atheletic populations. that is how you are extrapolating. Don't take me as being a smart arse with you, cause that isn't my intention at all.

Chemotherapy from non-small-cell lung carcinoma is what causes the muscle-wasting.

Enobosarm is currently being studied in two Phase 3 clinical trials, POWER 1 and
POWER 2, to prevent and treat muscle wasting in patients with NSCLC. In each of these
placebo-controlled, double-blind clinical trials, approximately 325 patients with stage III or
IV NSCLC have been randomized to oral daily doses of placebo or enobosarm 3 mg at
the time they began first-line standard platinum doublet chemotherapy. The POWER
trials are designed to assess the response rates of enobosarm versus placebo for the coprimary endpoints at three months of treatment on total lean body mass (muscle) assessed by DXA and physical function measured by the stair climb test (power).
Durability of enobosarm treatment will be assessed at five months. Secondary endpoints
include an assessment of whether enobosarm treated patients have an improved quality
of life and reduced healthcare resource utilization compared to placebo. Overall survival
is being assessed as an additional safety endpoint.

So please, if anything, the user running this as a test to halt any muscle wasting that might result from his inactivity is using this properly -albeit at nearly quadruple the dose (which isn't the point). The point is like booneman77 said,

IIRC the studies looked at exactly this: blunting muscle wasting. And when they saw positive results, that would confirm.
 
Chemotherapy from non-small-cell lung carcinoma is what causes the muscle-wasting.



So please, if anything, the user running this as a test to halt any muscle wasting that might result from his inactivity is using this properly -albeit at nearly quadruple the dose (which isn't the point). The point is like booneman77 said,

I understand what point you are trying to convey here. My point is it is a completely different situation where a patient in a diseased state is suffering muscle loss due to the cancer or the chemo whatever. In a healthy person who undertakes resistance training causes the body to adapt to these stressors through hyperthrophy etc, when that stressor is removed why would the body hold onto this muscle?
 
Alright man not gonna go further with this with you. But i will say there is a difference with preventing muscle wasting for a person in a diseased state for holding onto essential muscle vs a meathead who isnt providing resistance stimuli wanting to keep his muscles.

The end.

I ordered some iron flex formabolic, what would be a low dose to use along with the ostarine?
 
I ordered some iron flex formabolic, what would be a low dose to use along with the ostarine?

Not at 15mg. NoAddedHmones is too high strung. You can take it but it will inhibit the aromatase enzyme, thus negating some of the positive benefits of ostarine.

You can if you want, but at 15mg I think it's probably overkill. Plus, wouldn't you want to gauge your results on a solo run just for future reference?
 
I ordered some iron flex formabolic, what would be a low dose to use along with the ostarine?

The advice Noadded gave you is fine if you start to feel heavy estro side but you should be good.
 
Not at 15mg. NoAddedHmones is too high strung. You can take it but it will inhibit the aromatase enzyme, thus negating some of the positive benefits of ostarine. You can if you want, but at 15mg I think it's probably overkill. Plus, wouldn't you want to gauge your results on a solo run just for future reference?

Lol enough man. Im done in here. Listen to the guy who complaining about a host of sides hes experienced on osta using an irresponsible dosage.
 
The only way we learn is through experimentation.

Your brash attitude doesn't benefit anyone.

Take care now, bye bye then.
 
I'd personally hold off on the AI's until you really feel they're necessary.

I had zero reason to think my estrogen was out of whack at 20mg.
 
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Not at 15mg. NoAddedHmones is too high strung. You can take it but it will inhibit the aromatase enzyme, thus negating some of the positive benefits of ostarine.

You can if you want, but at 15mg I think it's probably overkill. Plus, wouldn't you want to gauge your results on a solo run just for future reference?

My one concern is, I am also taking propecia and have been for 20 yrs. I've never really had any sides other than some low libido. But in reading I see where finesteride does Increase estrogen. So if ostarine also increases estrogen, I'm just not wanting breasts! Lol
 
'

My one concern is, I am also taking propecia and have been for 20 yrs. I've never really had any sides other than some low libido. But in reading I see where finesteride does Increase estrogen. So if ostarine also increases estrogen, I'm just not wanting breasts! Lol

See, I read posts like this and then try to bring examples to the table. Like this:

Enobosarm: A targeted therapy for metastatic, androgen receptor positive, breast cancer.

Abstract:

Background: The androgen receptor (AR) is the most highly expressed steroid receptor in breast cancer (BC) with 75-95% of estrogen receptor positive (ER+) and 50% of ER negative BCs expressing AR. Prior studies have shown that women with metastatic BC (MBC) who are progressing on tamoxifen subsequently respond to non-tissue-selective, synthetic androgens with overall response rates of 20-60%. Unfortunately steroidal androgens have unwanted virilizing effects which limit clinical use. Enobosarm, a nonsteroidal, tissue-selective, AR modulator (SARM), provides a novel targeted approach to exploit the therapeutic benefits of AR activation without virilization or estrogenic effects. Methods: A proof of concept, phase II study is examining efficacy and safety of enobosarm 9mg daily in 22 postmenopausal women with ER+ MBC who previously responded to adjuvant and/or salvage endocrine therapy. Treatment continues until disease progression (PD). Primary endpoint is clinical benefit response (CBR) by 6 months (m) defined as patients (pts) having a complete response (CR), partial response (PR), or stable disease (SD). CBR will be correlated with AR status of metastatic tumor biopsy. Serum prostate specific antigen (PSA) will be evaluated as a biomarker of AR activity. Results: Pt demographics: mean age 63.7 years, mean time from diagnosis 11 years, 68% prior chemo, 94% (15/16) AR+. After a median f/u of 85 days (d) (range 84-209d), preliminary results of 16 pts: 8 SD as best response, median duration 4.5m; 9 PD after a median 84d. Among pts who reached 6m, 3 are AR+ with SD and increased PSA. 7 have yet to reach 6m and no CR or PR has been observed. Enobosarm is well-tolerated, with no drug related serious adverse events. Conclusions: Enobosarm is well tolerated and demonstrates promise as a novel targeted therapy for AR+ MBC. The primary endpoint has been achieved, with 3/15 AR+ pts meeting statistical threshold for success. Serum PSA appears to be a surrogate marker for AR activity and disease response. Final analysis is due in June 2014. Clinical trial information: NCT01616758.

So basically I see this (especially the bold part) and all I can surmise is that we don't have ostarine on our hands and rather something else. Which would make sense because this is a drug in Phase III clinical trials. I can see RC sites selling this because they can get away with it under the guise of "not intended for human consumption." But supplement companies... uhm....

Per your question, the first real sign of estrogen should be general poofyness (in the face, around the gut).
Topical forma has an hl of 12 hours so take that info and the dosing that McCrew530 laid out and run with it.

Source: Invalid Link Removed
 
Went down to 10mg today. Feel better so I guess I'll keep it there and keep exemestane at 25mg for a couple more days then back to 12.5
 
See, I read posts like this and then try to bring examples to the table. Like this:





So basically I see this (especially the bold part) and all I can surmise is that we don't have ostarine on our hands and rather something else. Which would make sense because this is a drug in Phase III clinical trials. I can see RC sites selling this because they can get away with it under the guise of "not intended for human consumption." But supplement companies... uhm....

Per your question, the first real sign of estrogen should be general poofyness (in the face, around the gut).
Topical forma has an hl of 12 hours so take that info and the dosing that McCrew530 laid out and run with it.

Source: Invalid Link Removed


The legitimacy of OTC Osta has crossed my mind. But I'm curious what it could be. I feel I had undeniable results and like zero side effects. I have pretty noticeable side effects from 1-DHEA, even.
 
Yeah I was wondering about the legitimacy as well.. I experienced puffy nips after about a week. Not sure what other compound it would be though. My blood pressure has been fine the whole time.
 
Well you are using data based on people with a disease which leads to loss of LBM and using the findings on this to theorize that these results will be seen in healthy atheletic populations. that is how you are extrapolating. Don't take me as being a smart arse with you, cause that isn't my intention at all.
so what you're saying is that a person who does not have a muscle wasting disease will see no benefit (even just maintenance of current mass) from an anabolic substance.
 
Surely there's no way a suppliment company like OL can put one thing on the ingredients label and another in the actual ****ing capsule???
getting a bit pissed. though still pleased with gains. tapering to 15mg in 5th week (next week) and possibly finishing then...
 
Surely there's no way a suppliment company like OL can put one thing on the ingredients label and another in the actual ****ing capsule???
getting a bit pissed. though still pleased with gains. tapering to 15mg in 5th week (next week) and possibly finishing then...

You're getting a bit pissed but pleased with gains? The product is working and you are getting pissed? I don't think I'm understanding your post haha...

You are absolutely correct though, there is no way that would happen. Let's look at the process that would go into doing such a ridiculous thing and then ask yourself why a successful supplement company such as OL would do such a thing.

1. We purity test every batch. This costs us money, every single time we test new batches. Why would we spend the money to test our raws if we were offering anything less than not only acceptable but extremely high quality raw powders? That would make zero sense. Why would a supplement company with staying power like us intentionally try to lead customers astray? Is that a sustainable business plan?

2. We operate with a manufacturing process that only allows for a 10% variance rate. This is done by machines, meaning, we would legitimately have to, after the caps have been produced, go to the manufacturer, unseal a few bottles, take the cotton out, pick a few capsules, and dump only 1/4 of them out. Then, we would have to put the caps back together, put the cotton back in, put a seal on the bottle, put the lid on and THEN reseal the shrink wrap seal.

I've been on these boards for years, I've seen 100's of members come and go. Being around that long has allowed me to coin a little term called forum mentality. Forum mentality is essentially mob placebo effect. Once one person says something, then another one starts to think it and it begins to snowball.

Here's the thing, there are so many variables to fitness that there a number of things that could be at play leading people to not see the results they'd like to, especially when dealing with hormones. No one has any idea how each specific individual is going to react to any hormone or any substance that operates on hormones. By taking one hormone, you are going to affect another hormone or the biosynthesis of one. This hormone could be prolactin, it could be DHT or it could be estrogen or any other number of endogenous hormones. The dynamics of hormones aren't as easy as "oh, I'll take this and the only possible outcome will be this." Yes, for a lot of people it does happen that way but for those it doesn't, there is the possibility of a negative outcome. This is a risk when using ANYTHING hormonal.

This is when people start to go around and attempt to take shots at the company "I only gained 11 lbs, this hormone is underdosed." It happens, that's the way of the business world. Not one supplement company now or past has 100% positive reviews, it's just not realistic.

Here is what I recommend to all forum members, and is something I have always recommended, think for yourself. Read up on **** all on your own instead of going into a thread and taking one persons opinion as fact.

Also, if a product doesn't work, let the company know, any company. Don't throw a hissey fit and start attempting to discredit them or their practices as a company. If at any point in time someone handled things in a professional manner and approached us with issues rather than immediately saying "it's underdosed, your purity this or that" we would happily and have happily worked with customers to get it right. You'll get better results with honey than vinegar.

Unfortunately, it only takes a few members or COMPETING companies to influence the minds of others and plant seeds that are simply completely unfounded and absurd. We can't control them nor the way they choose to conduct themselves and or represent a company. All we can do is keep doing what we're doing to keep up our INCREDIBLY high satisfaction rate by continuing to do everything we do day in and day out to focus our attention on OUR consumers.

Like BigSwole the owner of Omega said on another board, he knows the owner and vouches for him. I know the owner and vouch for him. A ton of people that have been in the industry know and vouch for OL. You'd be surprised how deep OL's ties go hahaha I'm still surprised by it daily and question him about it lol. BigSwole also said the prices we're offering CONQU3R at is "suicide... offering it for pennies on the dollar" but that we're (OL) doing it for the customer.

The made up ideas that we're underdosing anything or not using the highest purity available, at the best prices available are completely and entirely false. That is evident in our business plan, our prices, transparency and the lengths we go to "pennies on the dollar" for our customers.
 
So yesterday evening when I got home my nipples were puffier than they had ever been, so I stopped taking osta today and took 50mg clomid, along with 25mg aromasin again. They still feel sensitive, heavy and puffy at times but I'm getting really dehydrated throughout the night with stiff joints, so I can hopefully assume the aromasin is legit. Woke up with dry almost bloody nose this morning.

One thing to note is that SERMs always make my nipples puffy when I take them too, so it could be that as well since I was on nolva and now clomid.

If the puffiness continues to get worse or I start getting pain what do you guys suggest? Only thing "pharma" I have is ralox and letro made by cipla. Ralox gives me breast pain too though, apparently it's one of the rarer side effects. I've tested this by taking it alone off cycle. I'm afraid to take letro cause of the rebound making it worse. Last year I tried to reverse my slight gyno with letro and got some rebound even when on the ralox.

So far I'm not getting any acne or any other "high estro sides other than the puffy nipples and tenderness.
 
So yesterday evening when I got home my nipples were puffier than they had ever been, so I stopped taking osta today and took 50mg clomid, along with 25mg aromasin again. They still feel sensitive, heavy and puffy at times but I'm getting really dehydrated throughout the night with stiff joints, so I can hopefully assume the aromasin is legit. Woke up with dry almost bloody nose this morning.

One thing to note is that SERMs always make my nipples puffy when I take them too, so it could be that as well since I was on nolva and now clomid.

If the puffiness continues to get worse or I start getting pain what do you guys suggest? Only thing "pharma" I have is ralox and letro made by cipla. Ralox gives me breast pain too though, apparently it's one of the rarer side effects. I've tested this by taking it alone off cycle. I'm afraid to take letro cause of the rebound making it worse. Last year I tried to reverse my slight gyno with letro and got some rebound even when on the ralox.

So far I'm not getting any acne or any other "high estro sides other than the puffy nipples and tenderness.

Did you ever taper the letro down?
 
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