Odd SERM Results

dhickey

New member
I've done a few SERM runs before, HCG mono and full TRT. I've always had to be on an AI. Before starting any of this, my E2 was a little high with no hormone manipulation. I was coming off an HCG mono run where I was taking 25mg aromasin MWF to keep E2 under control. Started Adex instead because I had some on hand.


Feb 26th.

20mg Nolva ED
Tapering off HCG - can't recall what I was taking.
Adex .5mg twice a week.
Mod GRF and GHRP-2 at night for sleep. Maybe 3 of 4 nights a week.
Frag 176-191 at night and before workouts.
Cialis 5mg per day or as needed.

Total T - 422 ng/dl (348-1197)
Free T - 13.2 pg/ml (8.7-25.1)
DHEA-S - 435 pg/ml (102-416)
E2 - <6 (7.6-42.6)

Pretty standard AI dose for me, so I was surprised E2 was so low. Always had issues with E2. DHEA is usually on high end even with no supplementation.


March 20

20mg Nolva ED
NAC and IC3 for liver support because I was worried about running no AI
Mod GRF and GHRP-2 at night for sleep. Maybe 3 of 4 nights a week.
Frag 176-191 at night and/or before workouts.
Cialis 5mg per day or as needed.
Just started taking Forskolin to support DHEA to T conversion.

LH - 8.6 (1.7-8.6)
FSH - 6.4 (1.5-12.4)
Total T - 612 ng/dl (348-1197)
E2 - <6 pg/ml (7.6-42.6)

I have absolutely zero libido. Hot girlfriend with a healthy libido and mine is completely absent. So bizarre that E2 is that low. The only thing I can think of is that my research chem cialis was mislabeled and is an AI. Unlikely, but this is just baffling. I'll definitely stop the IC3, but doubt that will make a difference. I suppose I could take some DHEA to try and bump E2 but I'm already on the high end there. Any thoughts?
 
Only other change has been liposomal Vit C. Maybe 3g per day or so. Also take Metagenics licorice plus for adrenals, but I've taken that before in the past.
 
dhickey said:
Only other change has been liposomal Vit C. Maybe 3g per day or so. Also take Metagenics licorice plus for adrenals, but I've taken that before in the past.
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Extremely odd, especially considering licorice is a phytoestrogen/estrogen mimicker, yet Vitamin C can inhibit aromatization. The licorice might have altered your liver breakdown of estrogen though, as it affects multiple liver enzymes and the adrenals interact with these enzymes.
 
May want to have a repeat analysis done on e2. Could have been a lab error and actually just be the opposite.
 
The Matrix said:
May want to have a repeat analysis done on e2. Could have been a lab error and actually just be the opposite.
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Just tested again after going back to T at 150 per week and E2 still too low to even register. T at 800 and free T at 38 (high) Always have low SHBG so those results are expected. DHEA was also high which is not unusual. Hadn't been taking much licorice plus before this.

Also taking epi-andro. Never expected E2 to still be low or would have held off on that.

Thinking my SERM was prob a mislabeled AI. Would any of the suicide inhibitors have shut me down for that long?
 
Not sure if it's related but I've developed digestion issues. I get incredibly bloated and gassy anytime I eat. Even a small snack. Doc thought it was some antibiotics I was on a few months ago. I take probiotics. Tested negative for c-diff. Tested negative for gluten and dairy allergies.
 
dhickey said:
Not sure if it's related but I've developed digestion issues. I get incredibly bloated and gassy anytime I eat. Even a small snack. Doc thought it was some antibiotics I was on a few months ago. I take probiotics. Tested negative for c-diff. Tested negative for gluten and dairy allergies.
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You sound a lot like me, we're probably experiencing the same issue ..
 
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