Depression can lead to low sex-drive....Some supplement use can lead to depression. When I'm down in the dumps, I have no sex drive. Are you married, or have a partner? Sex is better with love and emotion. My girlfriend is great in bed and I'm comfortable with her-she is also comfortable with me. I've had random sex at times in my life, but it wasn't that great. Maybe you just have to find someone that you are attracted to and with love, the sex drive may return. Supplements can only help certain things-Whatever you do, the more you focus on a problem and stress, it will only get worse. Good luck