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No grapefruit with RRY?

RedwolfWV

RedwolfWV

Registered User
I was recently told to not eat or drink grapefruit while using red rice yeast, however no explaination was given. I cant find anything on the net about this. Anyone else ever hear this?
 
I have been warned about eating or drinking Grapefruit when taking certain medications. I think it has something to do with the Type of acid that is in grapefruit and how it reacts when combined with stomach acid and other products.
 
I think it has to do w/a chemical in grapefruit that suppresses a liver enzyme that breaks things down. Basically, you will get waaaaay more of the active into your system which could result in a toxic dose. There are several supps that contain this chemical but I don't think I'd ever mess w/ it.
 
Bionic said:
I think it has to do w/a chemical in grapefruit that suppresses a liver enzyme that breaks things down. Basically, you will get waaaaay more of the active into your system which could result in a toxic dose.
Click to expand...
That's it there. Grapefruit contains bergamottin, which inhibits an enzyme (I think CYP-450) responsible for breaking down substances in the liver. It also container narinigin, which can extend the 1/2 life of some medications (not sure which, but I believe many stimulants would be on that list).
 
Interesting. Thanks for the info guys. I'll keep looking and post if I find any additional information on it.
 
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