nicotine and lifting
- Thread starter tpol
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B5150
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tpol
New member
Thank you!
tpol
New member
Well from a smokeless tabacco user I can tell you there are many negatives to it, but from this article for the lifting part no, thanks again this was by far the most helpful the other 5-6 were basically people arguing back and forth
ZiR RED
Well-known member
I posted this in another thread a few days ago. These are just the endocrine effects of nicotine and how they may effect lifting performance......
I can't find the post, so I'll quickly recap.
First, nicotine is a vasoconstrictor. So it may reduce blood flow/circulation.
But, theres a lot more negatives that affect muscle gain than just that. Read on..................
Nicotine also effects the hypothalamus-pituitary axis.
Nicotine stimulates the release of ACTH (adrenal corticotropic hormone..which increases cortisol release).
Acute nicotine consumption stimulates prolactin levels.
And nicotine increases the hormone arginine vasopressin, which may in part be while nicotine acts as a vasoconstrictor.
Next, Nicotine acts on the adrenal axis, stimulating the production and release of glucocorticoids (cortisol).
Nicotine also stimulates an increase in epinephrine (adrenalin).
While these hormones are good during exercise, post exercise they delay the recovery process (i.e: inhibit protein and glycogen synthesis).
Additionally, nicotine stimulates the sympathetic nervous system, furthering the rise in catecholamines (adrenalin), and increased heart rate and vasoconstriction.
While smoking does not seem to affect total testosterone, it does increase estradiol and SHGB (thus, may reduce free test). It also seems to decrease sperm motility.
One of the chemicals in smoke (thiocynates) inhibits thyroid production; however the effects of cigarettes on the thyroid is a bit confusing. Some studies have shown increased thyroid hormone production while others have shown reduce...and yet, some have shown to effect at all. Either way, correct thyroid levels are important to muscle building as too much or too few will reduce protein synthesis.
Smoking may also affect beta cells in the pancreas, especially in men. Smoking has been shown to promote insulin resistance, either by affecting insulin producing cells or via elevated stress hormones, or both.
And as you may or may not know, insulin signalling is one of the most anabolic events in our bodies.
Finally, cigarette smoking reduces gastric emptying time. The reason many drink a shake post workout is to deliver protein and cho quickly into the blood stream to signal protein synthesis, recovery, and growth. So, smoking may reduce the "window of opportunity".
Br
I can't find the post, so I'll quickly recap.
First, nicotine is a vasoconstrictor. So it may reduce blood flow/circulation.
But, theres a lot more negatives that affect muscle gain than just that. Read on..................
Nicotine also effects the hypothalamus-pituitary axis.
Nicotine stimulates the release of ACTH (adrenal corticotropic hormone..which increases cortisol release).
Acute nicotine consumption stimulates prolactin levels.
And nicotine increases the hormone arginine vasopressin, which may in part be while nicotine acts as a vasoconstrictor.
Next, Nicotine acts on the adrenal axis, stimulating the production and release of glucocorticoids (cortisol).
Nicotine also stimulates an increase in epinephrine (adrenalin).
While these hormones are good during exercise, post exercise they delay the recovery process (i.e: inhibit protein and glycogen synthesis).
Additionally, nicotine stimulates the sympathetic nervous system, furthering the rise in catecholamines (adrenalin), and increased heart rate and vasoconstriction.
While smoking does not seem to affect total testosterone, it does increase estradiol and SHGB (thus, may reduce free test). It also seems to decrease sperm motility.
One of the chemicals in smoke (thiocynates) inhibits thyroid production; however the effects of cigarettes on the thyroid is a bit confusing. Some studies have shown increased thyroid hormone production while others have shown reduce...and yet, some have shown to effect at all. Either way, correct thyroid levels are important to muscle building as too much or too few will reduce protein synthesis.
Smoking may also affect beta cells in the pancreas, especially in men. Smoking has been shown to promote insulin resistance, either by affecting insulin producing cells or via elevated stress hormones, or both.
And as you may or may not know, insulin signalling is one of the most anabolic events in our bodies.
Finally, cigarette smoking reduces gastric emptying time. The reason many drink a shake post workout is to deliver protein and cho quickly into the blood stream to signal protein synthesis, recovery, and growth. So, smoking may reduce the "window of opportunity".
Br
MattPorter
Banned
^ smoking as in cigarettes and the accompanying carcinogens and toxins.
Pure nicotine has shown to have anti-estrogenic effects.
Aromatase inhibitors in cigarette smoke, tobacco leaves and other plants.
Osawa Y, Tochigi B, Tochigi M, Ohnishi S, Watanabe Y, Bullion K, Osawa G, Nakabayashi Y, Yarborough C.
Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro.
Barbieri RL, Gochberg J, Ryan KJ.
-Matt
Pure nicotine has shown to have anti-estrogenic effects.
Aromatase inhibitors in cigarette smoke, tobacco leaves and other plants.
Osawa Y, Tochigi B, Tochigi M, Ohnishi S, Watanabe Y, Bullion K, Osawa G, Nakabayashi Y, Yarborough C.
Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro.
Barbieri RL, Gochberg J, Ryan KJ.
-Matt
ZiR RED
Well-known member
Ok, and that could explain the effects of nicotine on damaging blood lipids, since physiological levels of E2 are important for a number of reasons.
Still, its the nicotine that causes an increase in stress hormones, not the carcinogens in cigarette smoke.
Br
tpol
New member
I actually read this it was. Nicotine vs diet I think? It became a argument thread lol
MattPorter
Banned
I use nicotine ONLY when dieting for a show and ONLY during final 6 weeks when I am super low on bf%
It helps my mood from increase in dopamine and also helps satiate me while non-stop hungry.
If you have enough hormone in blood --- the cortisol effect is liberating fatty acids into blood stream for oxidation.
Definitely not "good" but when dieting for bodybuilding contests -- realistically NOTHING is good nor healthy at that level.
Wrote this while buzzing on 4mg nicotine pre-contest -- Invalid Link RemovedMatt
It helps my mood from increase in dopamine and also helps satiate me while non-stop hungry.
If you have enough hormone in blood --- the cortisol effect is liberating fatty acids into blood stream for oxidation.
Definitely not "good" but when dieting for bodybuilding contests -- realistically NOTHING is good nor healthy at that level.
Wrote this while buzzing on 4mg nicotine pre-contest -- Invalid Link RemovedMatt
tpol
New member
ZiR RED
Well-known member
My issue with this article is your discussion of brown adipose tissue. BAT is not abundant in humans. In fact, the little that adults have and the amount it contributes to decreasing body fat is minimal. These cells burn off the fat located in them to produce heat, specifically during and when waking up from hibernation, or when facing a cold stress. Under times of caloric deficit, or when epi and/or cort is high, BAT does not take up fats and oxidize it as say, a skeletal muscle would.
My main concern with nicotine is the adrenal fatigue and the chronic elevations in cortisol. Acute cortisol spike during exercise is good. This liberates fuel. Chronic elevations in cort at rest are not good. This blunts protein synthesis, reduces glucose uptake, promotes insulin resistance, and hurts nutrient partitioning and body composition.
So nicotine reduces your appetite. Big deal.
Exercise some self control. Own your bull**** and change your behavior.
Br
steppinRazor
Well-known member
why?? do you feel like you do better if theres low nicotine in your blood?
i always smoke right before i hit the gym..in some cases chain smoke 2 cigs on the way..always one after my post WO protein shake too..sooo satisfying. its one of the only bad habbits i still have left. gave up drinking a year and a half ago.
Eberly
Banned
Great posts.I agree with you completely.
Eberly
Banned
Yes, I agree with you completely, that is the purpose of this thread.
MattPorter
Banned
The half-life is 60 minutes or so --- so it wont be a chronic issue.
"most" who are dieting to extreme levels are assisted by anabolic agents which keep anabolism high and catabolism low.
Also -- most who are dieting to extreme levels take caffeine and beta 2 agonist which also add to the effects of nicotine.
Not recommending it, I just do not see it as bad as people make it out to be. If you use it INfrequently in LOW doses w/ the right compounds it can aid in satiation, thermogenesis and mild aromatase control.
-Matt
ZiR RED
Well-known member
Ok, so we are getting closer to the same page. I agree it has its uses, you (seem) to agree that it can have negatives.
I wouldn't quantify most people who are dieting to extreme levels (i.e: bodybuilders) as using anabolic agents, however. There are still a large portion of people who compete naturally.
Br
Eberly
Banned
Who taught you this?
MattPorter
Banned
I believe I was experimenting with this in 2003, back when bromocriptine and leptin was a huge topic.
I tried the nicotine snuff that you'd snort intra nasally but hated that --- then tried the gum and it worked nicely.
-Matt
SoupNaziNazi
Active member
Digging this one out of the grave. I have some questions, so would chewing on a 4mg piece of gum during training be beneficial as to a stimulant effect? And would adding say a 2mg piece of gum with 12.5 mg of ephedrine and 100mg of caffeine provide a mild nootropic effect for studying? U said they work together so I was just curious. I don't use stims to often so that's why I suggested the half doses of all those substancea
KrisL
Active member
Wikipedia says 2mg pieces provide 1mg nicotine and the 4mg ones provide 3mg nicotine.
"One milligram of nicotine has a pronounced thermogenic effect, which can be increased by ≈100% by adding 100 mg caffeine. Increasing the nicotine dose to 2 mg does not increase the thermogenic effect but produces side effects in most subjects. " Invalid Link Removed
As for nootropic effect: Invalid Link Removed
SoupNaziNazi
Active member
So would am ephedrine, caffeine, and nicotine stack be pretty sick for fat loss? Maybe 25/200/4? And if so would that be effective at only one dose in the morning or 2 doses a day?
SoupNaziNazi
Active member
Solid, thanks for the reply
SoupNaziNazi
Active member
Does anyone know if cutting a piece of nicotine gum in half would ruin the half ur saving for later?
